[1]展帮乐,阮建波,朱和玲,等.生殖器疱疹高危人群两种血清学检测方法阳性率的比较[J].医学信息,2019,(17):178-179.[doi:10.3969/j.issn.1006-1959.2019.17.061]
 ZHAN Bang-le,RUAN Jian-bo,ZHU He-ling,et al.Comparison of Positive Rates of Two Serological Tests for High Risk Population of Genital Herpes[J].Medical Information,2019,(17):178-179.[doi:10.3969/j.issn.1006-1959.2019.17.061]
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生殖器疱疹高危人群两种血清学检测方法阳性率的比较()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年17期
页码:
178-179
栏目:
诊疗技术
出版日期:
2019-09-01

文章信息/Info

Title:
Comparison of Positive Rates of Two Serological Tests for High Risk Population of Genital Herpes
文章编号:
1006-1959(2019)17-0178-02
作者:
展帮乐1阮建波2朱和玲2张 霞2周 湧2
1.南方科技大学医院皮肤科,广东 深圳 518055; 2.暨南大学附属东莞医院,广东 东莞 523899
Author(s):
ZHAN Bang-le1RUAN Jian-bo2ZHU He-ling2ZHANG Xia2ZHOU Yong2
1.Department of Dermatology, Southern University of Science and Technology Hospital, Shenzhen 518055,Guangdong,China; 2.Dongguan Hospital,Jinan University,Dongguan 523899,Guangdong,China
关键词:
生殖器疱疹单纯疱疹病毒化学发光免疫法酶联免疫法
Keywords:
Key words:Genital herpesHerpes simplex virusChemiluminescence immunoassayEnzyme-linked immunosorbent assay
分类号:
R752.1
DOI:
10.3969/j.issn.1006-1959.2019.17.061
文献标志码:
A
摘要:
目的 了解生殖器疱疹(GH)高危人群两种血清学检测方法的阳性率。方法 收集暨南大学附属东莞医院2018年1月~5月427例GH高危人群采用酶联免疫法,2018年7月~11月528例GH高危人群采用化学发光免疫法,比较两种检测方法检测单纯疱疹病毒(HSV)IgM阳性结果。结果 化学发光免疫法检测的528例GH高危人群中HSV IgM阳性94例,阳性率17.80%,其中1型IgM阳性42例,阳性率7.95%,2型IgM阳性52例,阳性率9.85%;酶联免疫方法检测的427例GH高危人群中HSV IgM阳性24例,阳性率5.62%,其中1型IgM阳性12例,阳性率2.81%,2型IgM阳性12例,阳性率2.81%。化学发光免疫法阳性率检测高于酶联免疫法,差异有统计学意义(P<0.05)。结论 化学发光免疫法检测高危GH人群HSV IgM的阳性率高于酶联免疫法,且操作简单,检测时间周期短。
Abstract:
Abstract:Objective To understand the positive rates of two serological tests for high-risk population of genital herpes(GH).Methods Collecting Dongguan Hospital Affiliated to Jinan University from January to May 2018, 427 high-risk population of GH were enrolled in enzyme-linked immunosorbent assay. 528 high-risk population of GH from July to November 2018 were chemiluminescence immunoassay. Two methods were used to detect IgM positive result of herpes simplex virus (HSV). Results 528 high-risk population of GH cases were detected by chemiluminescence immunoassay, with 94 cases of HSV IgM, the positive rate was 17.80%, including 42 cases of type I IgM positive, the positive rate was 7.95%; 52 cases of type 2 IgM positive, the positive rate was 9.85%; 427 high-risk population of GH cases were detected by enzyme-linked immunosorbent assay methods, with 24 cases of herpes simplex IgM, the positive rate was 5.62%, including 12 cases of type I IgM positive, the positive rate was 2.81%; 12 cases of type 2 IgM positive, the positive rate was 2.81%. The positive rate of chemiluminescence immunoassay was higher than that of enzyme-linked immunosorbent assay(ELISA), the difference was statistically significant (P<0.05). Conclusion The positive rate of herpes simplex virus IgM in high-risk genital herpes is higher than that of enzyme-linked immunosorbent assay (ELISA), and the operation is simple and the results are rapid.

参考文献/References:

[1]樊建勇,赵阳,杨慧兰.单纯疱疹病毒的生物学特点及其潜伏复发机制研究进展[J].皮肤性病诊疗学杂志,2015,22(1):82-85. [2]钟道清,周天恩.肥大细胞在HSV-2感染所致生殖器疱疹中的作用[J].皮肤性病诊疗学杂志,2018,25(3):128-131. [3]柯吴坚,杨斌.2015年美国CDC生殖器疱疹治疗指南解读[J].中国皮肤性病学杂志,2016,30(5):530-533. [4]邹先彪.《2014英国生殖器疱疹指南》解读[J].中国临床医生杂志,2016,44(1):14-15. [5]何卫东,刘明春,陈秋月,等.化学发光法检测育龄妇女单纯疱疹病毒结果分析[J].中国卫生标准管理,2018,9(16):117-119.

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更新日期/Last Update: 2019-09-01