[1]何 静.上皮性卵巢癌化学治疗的研究[J].医学信息,2019,32(18):24-28.[doi:10.3969/j.issn.1006-1959.2019.18.009]
 HE Jing.Chemotherapy of Epithelial Ovarian Cancer[J].Journal of Medical Information,2019,32(18):24-28.[doi:10.3969/j.issn.1006-1959.2019.18.009]
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上皮性卵巢癌化学治疗的研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年18期
页码:
24-28
栏目:
综述
出版日期:
2019-09-15

文章信息/Info

Title:
Chemotherapy of Epithelial Ovarian Cancer
文章编号:
1006-1959(2019)18-0024-05
作者:
何 静
四川省肿瘤医院/四川省癌症防治中心/电子科技大学医学院附属肿瘤医院妇科肿瘤中心, 四川 成都 610041
Author(s):
HE Jing
Sichuan Cancer Hospital/Sichuan Cancer Prevention Center/Gynecological Oncology Center, Affiliated Tumor Hospital, School of Medicine,University of Electronic Science and Technology of China,Chengdu 610041,Sichuan,China
关键词:
上皮性卵巢癌恶性肿瘤分子机制化学治疗耐药性
Keywords:
Key words:Epithelial ovarian cancerMalignant neoplasmsMolecular mechanismChemotherapyDrug resistance
分类号:
R737.31
DOI:
10.3969/j.issn.1006-1959.2019.18.009
文献标志码:
A
摘要:
卵巢癌是中青年女性中第二大高发恶性肿瘤,超过2/3的患者被诊断时即为卵巢癌晚期,90%以上的卵巢恶性肿瘤来源于上皮性卵巢癌(EOC)。晚期EOC的初始标准化治疗是最大限度的肿瘤细胞减灭术及术后顺铂和紫杉醇为主的联合化疗方案。如何正确认识及防治EOC,以提高患者治疗效果和降低化学治疗药物的耐药性是当前临床上亟待解决的问题。本文从EOC的流行病学及发病因素、分子机制及化学治疗三个方面进行论述,为临床上治疗EOC提供理论依据。
Abstract:
Abstract:Ovarian cancer is the second most common malignant tumor among young and middle-aged women. More than two-thirds of patients are diagnosed with advanced ovarian cancer, and more than 90% of ovarian malignancies are derived from epithelial ovarian cancer (EOC). The initial standardized treatment of advanced EOC is maximal cytoreductive surgery and postoperative cisplatin and paclitaxel-based combination chemotherapy. How to correctly understand and prevent EOC to improve the treatment effect of patients and reduce the drug resistance of chemotherapeutic drugs is a problem that needs to be solved urgently in clinical practice. This article discusses the epidemiology and pathogenesis factors, molecular mechanism and chemotherapy of EOC, and provides theoretical basis for clinical treatment of EOC.

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更新日期/Last Update: 2019-09-15