[1]王晓燕,梁 萍,董艳婷.非特异性免疫疗法在支气管哮喘治疗中的应用进展[J].医学信息,2019,(05):57-60.[doi:10.3969/j.issn.1006-1959.2019.05.018]
 WANG Xiao-yan,LIANG Ping,DONG Yan-ting.Progress in the Application of Non-specific Immunotherapy in the Treatment of Bronchial Asthma[J].Medical Information,2019,(05):57-60.[doi:10.3969/j.issn.1006-1959.2019.05.018]
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非特异性免疫疗法在支气管哮喘治疗中的应用进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年05期
页码:
57-60
栏目:
综述
出版日期:
2019-03-01

文章信息/Info

Title:
Progress in the Application of Non-specific Immunotherapy in the Treatment of Bronchial Asthma
文章编号:
1006-1959(2019)05-0057-04
作者:
王晓燕1梁 萍1董艳婷2
(1.北京卫生职业学院相关医学与管理系,北京 100053;2.山西医科大学第二医院呼吸与危重症医学科,山西 太原 030001)
Author(s):
WANG Xiao-yan1LIANG Ping1DONG Yan-ting2
(1.Department of Medicine and Management,Beijing Health Vocational College,Beijing 100053,China;2.Department of Respiratory and Critical Care Medicine,the Second Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi,China)
关键词:
支气管哮喘非特异性免疫疗法IgE单克隆抗体免疫疗法
Keywords:
Bronchial asthmaNon-specific immunotherapyIgE monoclonal antibodyImmunotherapy
分类号:
R691.3
DOI:
10.3969/j.issn.1006-1959.2019.05.018
文献标志码:
A
摘要:
支气管哮喘是呼吸系统的常见病及多发病之一,其是由嗜酸性粒细胞、肥大细胞、T淋巴细胞、中性粒细胞等多种细胞及细胞组分参与的气道慢性过敏反应炎症性疾病,在全球范围内的发病率及死亡率不断上升,严重影响公众健康和患者生活质量。研究发现,支气管哮喘的发病涉及机体免疫紊乱,Th1/Th2细胞比例失衡是哮喘发病的重要机制,在此基础上,支气管哮喘的免疫疗法取得一定进展,本文基于支气管哮喘的免疫学机制,对非特异性免疫疗法在支气管哮喘治疗中的研究及应用进展进行综述,以期为支气管哮喘的治疗提供新的方向和思路。
Abstract:
Bronchial asthma is one of the common and frequently-occurring diseases of the respiratory system. It is an airway chronic allergic reaction involving various cells and cellular components such as eosinophils, mast cells, T lymphocytes, and neutrophils. Diseases, global morbidity and mortality are rising, seriously affecting public health and the quality of life of patients. The study found that the incidence of bronchial asthma involves immune disorders, and the imbalance of Th1/Th2 cells is an important mechanism of asthma. On this basis, the immunotherapy of bronchial asthma has made some progress. Based on the immunological mechanism of bronchial asthma, this paper The research and application progress of heterosexual immunotherapy in the treatment of bronchial asthma are reviewed in order to provide new directions and ideas for the treatment of bronchial asthma.

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更新日期/Last Update: 2019-03-01