[1]林斯婕,吴 璇,覃 桓,等.卵巢癌合并2型糖尿病发生的危险因素分析[J].医学信息,2019,32(05):124-125.[doi:10.3969/j.issn.1006-1959.2019.05.039]
　LIN Si-jie,WU Xuan,QIN Huan,et al.Analysis of Risk Factors for Ovarian Cancer Complicated with Type 2 Diabetes[J].Medical Information,2019,32(05):124-125.[doi:10.3969/j.issn.1006-1959.2019.05.039]
点击复制

卵巢癌合并2型糖尿病发生的危险因素分析()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年05期
页码:
124-125
栏目:
临床研究
出版日期:
2019-03-01

文章信息/Info

Title:
Analysis of Risk Factors for Ovarian Cancer Complicated with Type 2 Diabetes
文章编号:
1006-1959（2019）05-0124-02
作者:
林斯婕1; 吴 璇1; 覃 桓2; 余立萍1
（1.三峡大学医学院，湖北 宜昌 443000；2.宜昌第一人民医院，湖北 宜昌 443000）
Author(s):
LIN Si-jie1; WU Xuan1; QIN Huan2; YU Li-ping1
(1.School of Medicine,Three Gorges University,Yichang 443000,Hubei,China;2.Yichang First People’s Hospital,Yichang 443000,Hubei,China)
关键词:
卵巢癌; 糖尿病; 高血压; 血脂
Keywords:
Ovarian cancer; Diabetes; Hypertension; Blood lipids
分类号:
R581.1；R737131
DOI:
10.3969/j.issn.1006-1959.2019.05.039
文献标志码:
A
摘要:
目的 研究卵巢癌合并2型糖尿病的危险因素。方法 选择2010年1月~2017年12月我院住院病历中出院诊断为卵巢癌合并2型糖尿病，经病理确诊的21例患者设病例组，另选择未合并糖尿病的卵巢癌患者47例设为对照组，收集患者临床资料，包括一般情况、生育史、月经史、避孕史、家族史和既往史等，并采用非条件Logistic回归分析。结果 单因素分析显示，高血压、盆腔囊肿和高脂血症等是卵巢癌合并2型糖尿病的危险因素。多因素分析显示与卵巢癌合并2型糖尿病发生显著关联的是盆腔囊肿和高脂血症，OR值分别为8.536（95%CI 1.386~52.556）、5.346(95%CI,1.069~26.738)。结论 卵巢癌合并2型糖尿病的发生发展受多种因素相互作用的影响。积极治疗盆腔囊肿和高脂血症，可预防和控制卵巢癌合并2型糖尿病的发生发展。
Abstract:
Objective To study the risk factors of ovarian cancer with type 2 diabetes. Methods From January 2010 to December 2017，21 patients were diagnosed with ovarian cancer complicated with type 2 diabetes as case group, 47 patients were diagnosed with ovarian cancer without type 2 diabetes as control group.The clinical data of the patients were collected, including general condition, birth history, menstrual history, contraceptive history, family history and past history, and unconditional logistic regression analysis was used. Results Univariate analysis showed that hypertension, pelvic cysts and hyperlipidemia were risk factors for ovarian cancer with type 2 diabetes. Multivariate analysis showed that ovarian cancer with type 2 diabetes was significantly associated with pelvic cysts and hyperlipidemia, with OR values of 8.536 (95% CI 1.386 to 52.556) and 5.346 (95% CI, 1.069 to 26.738), respectively. Conclusion The occurrence and development of ovarian cancer with type 2 diabetes is affected by the interaction of various factors. Active treatment of pelvic cysts and hyperlipidemia can prevent and control the occurrence and development of ovarian cancer with type 2 diabetes.

参考文献/References:


[1]Nasu K,Kai K,Hirakawa T,et al.Retrospective analysis of outcomes of secondary debulking surgery for recurrent epithelial ovarian cancer with favorable prognostic factors[J].J Obstet Gynaecol Res,2014(40):791-796.
[2]Akhavan S,Ghahghaei-Nezamabadi A,Modaresgilani M,et al.Impact of diabetes mellitus on epithelial ovarian cancer survival[J].BMC Cancer,2018(18):1246.
[3]Han KT,Cho GJ,Kim EH.Evaluation of the Association between Gestational Diabetes Mellitus at First Pregnancy and Cancer within 10 Years Postpartum Using National Health Insurance Data in South Korea[J].Int J Environ Res Public Health,2018,15(12):E2646.
[4]Tymon-Rosario JR,Miller EM,Gressel GM,et al.Association between diabetes mellitus and progression free survival in women with ovarian granulosa cell tumors[J].Gynecol Oncol Rep,2018(26):94-98.
[5]Gapstur SM,Patel AV,Diver WR,et al.Type Ⅱ diabetes mellitus and the incidence of epithelial ovarian cancer in the cancer prevention study-Ⅱ nutrition cohort[J].Cancer Epidemiol Biomarkers Prev,2012(21):2000-2005.
[6]Lega IC,Pole JD,Austin PC,et al.Diabetes Risk in Childhood Cancer Survivors:A Population-Based Study[J].Can J Diabetes,2018(42):533-539.
[7]Shah MM,Erickson BK,Matin T,et al.Diabetes mellitus and ovarian cancer: more complex than just increasing risk[J].Gynecol Oncol,2014(135):273-277.

相似文献/References:

[1]张西园.糖尿病与结直肠癌患者预后相关研究进展[J].医学信息,2018,31(01):55.[doi:10.3969/j.issn.1006-1959.2018.01.020]
　ZHANG Xi-yuan.Research Progress in the Relationship between Diabetes and the Prognosis of Colorectal Cancer[J].Medical Information,2018,31(05):55.[doi:10.3969/j.issn.1006-1959.2018.01.020]
[2]耿金萍.综合护理对甲状腺良性肿瘤并糖尿病患者手术效果的影响分析[J].医学信息,2018,31(01):163.[doi:10.3969/j.issn.1006-1959.2018.01.064]
　GENG Jin-ping.Analysis of the Effect of Comprehensive Nursing on the Surgical Effect of Thyroid Benign Tumor and Diabetic Patients[J].Medical Information,2018,31(05):163.[doi:10.3969/j.issn.1006-1959.2018.01.064]
[3]李雯婷,谈世华,余江明,等.踝肱指数检测在住院糖尿病患者中的重复性研究[J].医学信息,2018,31(03):159.[doi:10.3969/j.issn.1006-1959.2018.03.058]
　LI Wen-ting,TAN Shi-hua,YU Jiang-ming,et al.Study on Reproducibility of Ankle-brachial Index in Inpatients with Diabetes Mellitus[J].Medical Information,2018,31(05):159.[doi:10.3969/j.issn.1006-1959.2018.03.058]
[4]刘 静.冠状动脉粥样硬化性心脏病合并糖尿病的血脂检验结果分析[J].医学信息,2018,31(04):154.[doi:10.3969/j.issn.1006-1959.2018.04.057]
　LIU Jing.Analysis of Blood Lipid Test Results in Coronary Atherosclerotic Heart Disease Complicated with Diabetes Mellitus[J].Medical Information,2018,31(05):154.[doi:10.3969/j.issn.1006-1959.2018.04.057]
[5]谢勇丽,苏晓清,张雅薇.糖尿病痛性周围神经病变患者情绪调查分析[J].医学信息,2018,31(05):14.[doi:10.3969/j.issn.1006-1959.2018.05.005]
　XIE Yong-li,SU Xiao-qing,ZHANG Ya-wei.Investigation and Analysis of Mood in Patients with Diabetic Peripheral Neuropathy[J].Medical Information,2018,31(05):14.[doi:10.3969/j.issn.1006-1959.2018.05.005]
[6]张雅薇,朱明慧.首发为动眼神经麻痹的糖尿病合并动眼神经麻痹误诊为痛性眼肌麻痹1例分析[J].医学信息,2018,31(05):23.[doi:10.3969/j.issn.1006-1959.2018.05.008]
　ZHANG Ya-wei,ZHU Ming-hui.An Analysis of a Case of Diabetes Mellitus with Oculomotor Nerve Palsy Misdiagnosed as Painful Ophthalmoplegia[J].Medical Information,2018,31(05):23.[doi:10.3969/j.issn.1006-1959.2018.05.008]
[7]张宇宁.黄酮类化合物治疗糖尿病及其并发症的研究[J].医学信息,2018,31(05):50.[doi:10.3969/j.issn.1006-1959.2018.05.018]
　ZHANG Yu-ning.Study on Flavonoids in the Treatment of Diabetes Mellitus and its Complications[J].Medical Information,2018,31(05):50.[doi:10.3969/j.issn.1006-1959.2018.05.018]
[8]柳 梅.头孢哌酮钠舒巴坦钠治疗糖尿病并发尿路感染的 临床效果观察[J].医学信息,2018,31(07):139.[doi:10.3969/j.issn.1006-1959.2018.07.047]
　LIU Mei.Clinical Efficacy of Cefoperazone Sodium and Sulbactam Sodium in Treatment of Diabetes Complicated with Urinary Tract Infection[J].Medical Information,2018,31(05):139.[doi:10.3969/j.issn.1006-1959.2018.07.047]
[9]杨廷双.卵巢癌患者经CT检查和MRI检查的临床效果对比[J].医学信息,2018,31(07):153.[doi:10.3969/j.issn.1006-1959.2018.07.053]
　YANG Ting-shuang.Comparison of Clinical Effects between CT and MRI in Patients with Ovarian Cancer[J].Medical Information,2018,31(05):153.[doi:10.3969/j.issn.1006-1959.2018.07.053]
[10]吕桂英.影响糖尿病患者药物治疗依从性相关因素临床分析[J].医学信息,2018,31(08):109.[doi:10.3969/j.issn.1006-1959.2018.08.036]
　LV Gui-ying.Clinical Analysis of Factors Related to Compliance with Drug Therapy in Patients with Diabetes Mellitus[J].Medical Information,2018,31(05):109.[doi:10.3969/j.issn.1006-1959.2018.08.036]

更新日期/Last Update: 2019-03-01