[1]徐 良,王纾宜.鼻硬结病的临床特点及病理诊断研究[J].医学信息,2019,(05):167-169.[doi:10.3969/j.issn.1006-1959.2019.05.055]
 XU Liang,WANG Shu-yi.Clinical Characteristics and Pathological Diagnosis of Rhinoscleroma[J].Medical Information,2019,(05):167-169.[doi:10.3969/j.issn.1006-1959.2019.05.055]
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鼻硬结病的临床特点及病理诊断研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年05期
页码:
167-169
栏目:
诊疗技术
出版日期:
2019-03-01

文章信息/Info

Title:
Clinical Characteristics and Pathological Diagnosis of Rhinoscleroma
文章编号:
1006-1959(2019)05-0167-03
作者:
徐 良王纾宜
(上海复旦大学附属眼耳鼻喉科医院病理科,上海 200031)
Author(s):
XU LiangWANG Shu-yi
(Department of Pathology,Eye and ENT Hospital of Fudan University,Shanghai 200031, China)
关键词:
硬结病六胺银
Keywords:
Rhinoscleroma Nose Hexamine silver
分类号:
R73;R76
DOI:
10.3969/j.issn.1006-1959.2019.05.055
文献标志码:
A
摘要:
目的 探讨鼻硬结病的临床特点及病理诊断价值。方法 收集2014年4月~2018年12月复旦大学附属眼耳鼻喉科医院10例硬结病患者资料进行回顾性分析,对硬结病临床、病理学特征及六胺银染色结果进行分析研究。结果 9例患者病变累及鼻部(1例同时累及气管,1例同时累及软腭),另1例侵犯会厌。最常见的症状为鼻塞(9例),其次为流涕(2例),鼻出血(2例),头痛(1例),嗅觉下降(1例),呼吸不畅(1例)及咽部异物感(1例)。通过六胺银染色显示,5例形态不典型硬结病病例中有4例短杆状菌体。结论 硬结病常累及上呼吸道,鼻腔是常见发病部位,六胺银特殊染色在硬结病病理诊断有较大作用,是诊断硬结病的重要辅助手段。
Abstract:
Objective To investigate the value of special staining of hexamine silver in diagnosis of scleroconjunctival disease.Methods The clinicopathological data of 10 cases of scleroderma were collected for retrospective analysis,and hexamamine silver staining was performed in the atypical cases.Results 4 out of 5 cases with atypical scleroderma showed short rods by silver hexamine staining.Conclusion The special staining of hexamamine silver plays a significant role in the pathological diagnosis of scleroderma and is an important auxiliary method for the diagnosis of scleroderma.

参考文献/References:


[1]Efared B,Hammas N,Gabrielle AE,et al.Rhinoscleroma: a chronic infectious disease of poor areas with characteristic histological features-report of a series of six cases[J].Trop Doct,2017,48(1):33-35.
[2]Ahmed AR,El-Badawy ZH,Mohamed IR,et al.Rhinoscleroma: a detailed histopathological diagnostic insight[J].Int J Clin Exp Pathol,2015,8(7):8438-8445.
[3]Suchanova PP,Mohyuddin NG,Rodriguez-Waitkus PM,et al.Rhinoscleroma in an urban nonendemic setting[J].Otolaryngol Head Neck Surg,2012,147(1):173-174.
[4]Fusconi M,Greco A,Cattaneo CG,et al.Social geography of Rhinoscleroma and qualitatively and quantitatively abnormal cell-mediated immunity[J].Infect Genet Evol,2018,62:17-19.
[5]邢海涛,李景远,曾重光.鼻硬结病高发家族4例[J].临床耳鼻咽喉科杂志,2001,15(11):488.
[6]钟琦,郭伟,张盛忠.鼻硬结病的临床及病理研究[J].中国耳鼻咽喉头颈外科,2016(7):374-376.
[7]Zhong Q,Guo W,Chen X,et al.Rhinoscleroma: a retrospective study of pathologic and clinical features[J].J Otolaryngol Head Neck Surg,2011,40(2):167-174.
[8]Canalis RF,Zamboni L.An interpretation of the structural changes responsible for the chronicity of rhinoscleroma[J].Laryngoscope,2001,111(6):1020-1026.
[9]de Pontual L,Ovetchkine P,Rodriguez D,et al.Rhinoscleroma: a French national retrospective study of epidemiological and clinical features[J].Clin Infect Dis,2008,47(11):1396-1402.
[10]李艺,张勉,叶辉信,等.鼻硬结病累及鼻腔鼻窦2例[J].临床耳鼻咽喉头颈外科杂志,2016,20:1652-1655.
[11]Fawaz S,Tiba M,Salman M,et al.Clinical, radiological and pathological study of 88 cases of typical and complicated scleroma[J].Clin Respir J,2011,5(2):112-121.
[12]Tan SL,Neoh CY,Tan HH.Rhinoscleroma: a case series[J].Singapore Med J,2012,53(2):e24-e27.

更新日期/Last Update: 2019-03-01