[1]朱 丹.不同锌制剂治疗小儿抗生素相关性腹泻的临床效果[J].医学信息,2019,32(09):147-148.[doi:10.3969/j.issn.1006-1959.2019.09.048]
　ZHU Dan.Clinical Effect of Different Zinc Preparations in the Treatment of Antibiotic-Associated Diarrhea in Children[J].Journal of Medical Information,2019,32(09):147-148.[doi:10.3969/j.issn.1006-1959.2019.09.048]
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不同锌制剂治疗小儿抗生素相关性腹泻的临床效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年09期
页码:
147-148
栏目:
药物与临床
出版日期:
2019-05-01

文章信息/Info

Title:
Clinical Effect of Different Zinc Preparations in the Treatment of Antibiotic-Associated Diarrhea in Children
文章编号:
1006-1959（2019）09-0147-02
作者:
朱 丹
（黑龙江省佳木斯市妇幼保健院小儿内科，黑龙江 佳木斯 154002）
Author(s):
ZHU Dan
(Department of Pediatrics,Jiamusi Maternal and Child Health Hospital,Jiamusi 154002, Heilongjiang,China)
关键词:
锌制剂; 抗生素相关性腹泻; 葡萄糖酸锌
Keywords:
Zinc preparation; Antibiotic-associated diarrhea; Zinc gluconate
分类号:
R725.7
DOI:
10.3969/j.issn.1006-1959.2019.09.048
文献标志码:
A
摘要:
目的 比较不同锌制剂治疗小儿抗生素相关性腹泻的临床效果。方法 选取我院2015年9月~2017年9月收治的抗生素相关性腹泻患儿90例作为研究对象，按照随机数字表法分成参照组和观察组，各45例。参照组予葡萄糖酸锌治疗，观察组予锌硒制剂治疗，比较两组治疗效果和临床症状消失时间。结果 观察组治疗总有效率高于参照组（95.56% vs 82.22%），且观察组发热、恶心呕吐、腹泻消失时间均短于参照组，差异具有统计学意义（P＜0.05）。结论 锌制剂对小儿抗生素相关性腹泻的临床治疗效果显著，其中锌硒制剂对小儿抗生素相关性腹泻的治疗效果优于葡萄糖酸锌制剂，能有效缩短患儿临床症状消失时间。
Abstract:
Objective To compare the clinical effects of different zinc preparations in the treatment of antibiotic-associated diarrhea in children. Methods A total of 90 children with antibiotic-associated diarrhea admitted to our hospital from September 2015 to September 2017 were enrolled in the study. According to the random number table method, they were divided into reference group and observation group, 45 cases each. The reference group was treated with zinc gluconate, and the observation group was treated with zinc selenium preparation. The treatment effect and the disappearance time of clinical symptoms were compared between the two groups. Results The total effective rate of the observation group was higher than that of the reference group (95.56% vs 82.22%). The fever, nausea and vomiting and diarrhea disappeared in the observation group were shorter than the reference group,the difference was statistically significant (P<0.05). Conclusion Zinc preparation has a significant clinical effect on antibiotic-associated diarrhea in children. Among them, zinc selenium preparation is better than zinc gluconate preparation in the treatment of antibiotic-associated diarrhea in children, which can effectively shorten the disappearance of clinical symptoms.

参考文献/References:

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更新日期/Last Update: 2019-05-01