[1]侯秋苹.重庆地区儿童CA-MRSA感染的危险因素研究[J].医学信息,2019,(19):134-135.[doi:10.3969/j.issn.1006-1959.2019.19.043]
 HOU Qiu-ping.Study on Risk Factors of Children's CA-MRSA in Chongqing[J].Medical Information,2019,(19):134-135.[doi:10.3969/j.issn.1006-1959.2019.19.043]
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重庆地区儿童CA-MRSA感染的危险因素研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年19期
页码:
134-135
栏目:
调查分析
出版日期:
2019-10-01

文章信息/Info

Title:
Study on Risk Factors of Children's CA-MRSA in Chongqing
文章编号:
1006-1959(2019)19-0134-02
作者:
侯秋苹
(重庆市第十三人民医院儿科,重庆 400053)
Author(s):
HOU Qiu-ping
(Department of Pediatrics,the 13th People's Hospital of Chongqing,Chongqing 400053,China)
关键词:
重庆地区儿童社区获得性耐甲氧西林金黄色葡萄球菌呼吸道感染危险因素
Keywords:
Chongqing areaChildrenCommunity acquiredMethicillin resistant staphylococcus aureusRespiratory infectionRisk factors
分类号:
R725.1
DOI:
10.3969/j.issn.1006-1959.2019.19.043
文献标志码:
A
摘要:
目的 研究重庆地区儿童社区获得性耐甲氧西林金黄色葡萄球菌(CA-MRSA)感染的高危因素,为临床预防儿童感染CA-MRSA提供参考。方法 选取2017年10月~2019年4月我院及其线路医院收治的200例呼吸道感染患儿作为研究对象。采用专用运输痰杯或拭子采样呼吸道感染患儿痰液或扁桃体分泌物,发热患儿则需进行血培养,检测标本并调查CA-MRSA发生情况及其危险因素。结果 200例呼吸道感染患儿中MRSA发生128例(64.00%),其中CA-MRSA发生55例,在MRSA中构成比为42.97%。单因素分析显示不同年龄、抗菌药物应用史、住院或就诊史的患儿CA-MRSA感染率比较,差异有统计学意义(P<0.05);多因素回归分析显示,年龄、抗菌药物应用史是CA-MRSA发生的独立高危因素。结论 重庆地区儿童CA-MRSA好发于5岁以下儿童,患儿普遍存在抗菌药物应用史,临床需加强对儿童CA-MRSA感染的重视,降低CA-MRSA的发病率与患病率。
Abstract:
Objective To study the high risk factors of community acquired-methicillin resistant Staphylococcus aureus (CA-MRSA) infection in children's in Chongqing, and provide reference for clinical prevention of CA-MRSA infection in children.Methods A total of 200 children with respiratory infection admitted to our hospital from October 2017 to April 2019 were selected as subjects. A special transport cup or swab is used to sample the respiratory tract infection of children's sputum or tonsil secretions. Children with fever need to undergo blood culture, test specimens and investigate the occurrence of CA-MRSA and its risk factors.Results Of the 200 children with respiratory infection, 128 (64.00%) had MRSA, of which 55 were CA-MRSA, and the ratio of MRSA was 42.97%. Univariate analysis showed that the rates of CA-MRSA infection among children of different ages, antibiotics application history, hospitalization or visit history were statistically significant (P<0.05). Multivariate regression analysis showed that age and antibacterial application history were Independent high risk factors for CA-MRSA.Conclusion CA-MRSA in children in Chongqing is prevalent in children under 5 years of age. The history of antibacterial use is widespread in children. It is necessary to strengthen the attention of children with CA-MRSA infection and reduce the incidence and prevalence of CA-MRSA.

参考文献/References:

[1]黄海林,王海平,祁红娟,等.某院社区获得性下呼吸道感染儿童金黄色葡萄球菌耐药情况分析[J].检验医学与临床,2018, 15(16):110-112. [2]邓超.儿童社区获得性肺炎耐甲氧西林金黄色葡萄球菌的耐药性及定植危险因素分析[J].临床合理用药杂志,2017,10(2):143-144. [3]Mediavilla JR,Chen L,Mathema B,et al.Global epidemiology of community-associated methicillin resistant Staphylococcus aureus(CA-MRSA)[J].Current Opinion in Microbiology,2012,15(5):588-595. [4]李茜,刘建华,王银,等.乌鲁木齐某医院社区获得性肺炎患儿金黄色葡萄球菌基因分型及耐药特征[J].华南国防医学杂志,2017,25(11):719-722. [5]高春燕,王振荣,高庆双,等.儿童社区获得性、金黄色葡萄球菌肺炎的分子分型研究[J].中国妇幼保健,2018,33(1):178-182.

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更新日期/Last Update: 2019-10-01