[1]陶雪莹,岑 超,何俐莹.盐酸氨溴索联合通窍鼻炎颗粒治疗幼儿分泌性中耳炎的临床效果[J].医学信息,2019,(20):145-146,149.[doi:10.3969/j.issn.1006-1959.2019.20.045]
 TAO Xue-ying,CEN Chao,HE Li-ying.Clinical Effect of Ambroxol Hydrochloride Combined with Tongqiao Rhinitis Granules in the Treatment of Secretory Otitis Media in Children[J].Medical Information,2019,(20):145-146,149.[doi:10.3969/j.issn.1006-1959.2019.20.045]
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盐酸氨溴索联合通窍鼻炎颗粒治疗幼儿分泌性中耳炎的临床效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2019年20期
页码:
145-146,149
栏目:
药物与临床
出版日期:
2019-10-15

文章信息/Info

Title:
Clinical Effect of Ambroxol Hydrochloride Combined with Tongqiao Rhinitis Granules in the Treatment of Secretory Otitis Media in Children
文章编号:
1006-1959(2019)20-0145-03
作者:
陶雪莹岑 超何俐莹
(重庆市妇幼保健院眼耳鼻喉科,重庆 400010)
Author(s):
TAO Xue-yingCEN ChaoHE Li-ying
(Department of Otolaryngology,Chongqing Health Center for Women and Children,Chongqing 400010,China)
关键词:
盐酸氨溴索通窍鼻炎颗粒分泌性中耳炎
Keywords:
Ambroxol hydrochlorideTongqiao rhinitis granulesSecretory otitis media
分类号:
R764.21
DOI:
10.3969/j.issn.1006-1959.2019.20.045
文献标志码:
A
摘要:
目的 观察盐酸氨溴索联合通窍鼻炎颗粒治疗幼儿分泌性中耳炎的临床效果。方法 选取2015年3月~2017年9月我院诊治的分泌性中耳炎患者120例(170耳),按照随机数字表法分为治疗组60例(90耳)与对照组60例(80耳)。对照组口服盐酸氨溴索,治疗组在对照组基础上加用通窍鼻炎颗粒,比较两组治疗前后咽鼓管功能正常占比、临床疗效及不良反应率。结果治疗后,治疗组咽鼓管功能正常占比为72.22%,高于对照组53.75%,差异具有统计学意义(P<0.05);治疗组总有效率为81.11%,高于对照组的62.50%,差异具有统计学意义(P<0.05);治疗组不良反应总发生率为8.33%,高于对照组的6.67%,但差异无统计学意义(P>0.05)。结论 盐酸氨溴索联合通窍鼻炎颗粒治疗幼儿分泌性中耳炎,可促进咽鼓管功能恢复正常,临床疗效确切,且无明显不良反应发生,安全有效。
Abstract:
Objective To observe the clinical effect of ambroxol hydrochloride combined with Tongqiao rhinitis granules in the treatment of secretory otitis media in children.Methods A total of 120 patients (170 ears) with secretory otitis media diagnosed in our hospital from March 2015 to September 2017 were enrolled. According to the random number table, 60 patients (90 ears) and 60 patients (80 ears) were included in the control group.The control group received oral ambroxol hydrochloride, and the treatment group added Tongqiao rhinitis granules on the basis of the control group. The normal proportion of eustachian tube function, clinical efficacy and adverse reaction rate were compared before and after treatment.Results After treatment, the normal proportion of eustachian tube function in the treatment group was 72.22%, which was higher than that in the control group 53.75%,the difference was statistically significant (P<0.05). The total effective rate of the treatment group was 81.11%, higher than that of 62.50% in control group,the difference was statistically significant (P<0.05). The total incidence of adverse reactions in the treatment group was 8.33%, which was higher than that of 6.67% in the control group, but the difference was not statistically significant (P>0.05).Conclusion Ambroxol hydrochloride combined with Tongqiao rhinitis granules in the treatment of secretory otitis media in children can promote the recovery of eustachian tube function, and the clinical curative effect is clear, and no obvious adverse reactions occur, which is safe and effective.

参考文献/References:

[1]Wu HL,Xie YR.Pathogenesis and current status of treatment of secretory otitis media[J].Acta Medicinae Sinica,2014,27(2):l51-153. [2]李大鹏,黄辉,何苗,等.分泌性中耳炎的临床诊治进展[J].中国耳科学杂志,2017,15(1):98-101. [3]侯薇,张铁英.盐酸氨溴索联合糖皮质激素治疗分泌性中耳炎的疗效观察[J].中国生化药物杂志,2017,37(7):191-193. [4]孔维佳.实用耳鼻咽喉头颈外科学[M].北京:人民卫生出版社,2010:1165-1170. [5]李英来,逯素艳,高永海.欧龙马滴剂治疗6~12个月婴儿分泌性中耳炎疗效和安全性研究[J].河北医药,2017,39(8):1248-1253. [6]雷静,吴小松.盐酸氨溴索联合桉柠蒎肠溶软胶囊治疗分泌性中耳炎的临床效果分析[J].西部医学,2016,9(28):1279-1282. [7]俞静,王雁.通窍鼻炎颗粒治疗鼻窦炎疗效观察[J].中国药师,2014,17(2):264-265. [8]徐艳,马梅,张宗强.通窍鼻炎颗粒联合针刺治疗过敏性鼻炎及对患者血清IL-4,IL-6及IL-10的影响[J].中国实验方剂学杂志,2015,21(14):169-171.

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更新日期/Last Update: 2019-10-15