[1]杨 健.银杏酮酯分散片治疗冠心病合并高血压的临床疗效[J].医学信息,2019,32(21):151-153.[doi:10.3969/j.issn.1006-1959.2019.21.050]
　YANG Jian.Clinical Efficacy of Ginkgo Ketone Ester Dispersible Tablets in the Treatment of Coronary Heart Disease Complicated with Hypertension[J].Journal of Medical Information,2019,32(21):151-153.[doi:10.3969/j.issn.1006-1959.2019.21.050]
点击复制

银杏酮酯分散片治疗冠心病合并高血压的临床疗效()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年21期
页码:
151-153
栏目:
中医中药
出版日期:
2019-11-01

文章信息/Info

Title:
Clinical Efficacy of Ginkgo Ketone Ester Dispersible Tablets in the Treatment of Coronary Heart Disease Complicated with Hypertension
文章编号:
1006-1959（2019）21-0151-03
作者:
杨 健
（北京市中关村医院心血管内科，北京 100190）
Author(s):
YANG Jian
(Department of Cardiology,Zhongguancun Hospital,Beijing 100190,China)
关键词:
冠心病合并高血压; 银杏酮酯分散片; 复方丹参片
Keywords:
Coronary heart disease with hypertension; Ginkgo ketone ester dispersible tablets;  Compound Danshen tablets
分类号:
R541.4
DOI:
10.3969/j.issn.1006-1959.2019.21.050
文献标志码:
A
摘要:
目的 探讨银杏酮酯分散片对冠心病合并高血压患者的临床疗效。方法 选择2018年1月~12月于我院就诊的100例冠心病合并高血压患者为研究对象，按照随机数字表法分为对照组和研究组，各50例，对照组采用苯磺酸氨氯地平片+厄贝沙坦联合复方丹参片治疗，研究组采用苯磺酸氨氯地平片+厄贝沙坦联合银杏酮酯分散片治疗，比较两组治疗前、治疗8周、3个月、6个月后的血压水平及临床疗效。结果 治疗8周后，两组血压均较治疗前改善，且研究组改善优于对照组，差异有统计学意义（P＜0.05）；治疗3个月及6个月后，研究组血压水平持续稳定，对照组血压水平呈升高趋势，研究组血压水平低于对照组，差异有统计学意义（P＜0.05）；研究组治疗总有效率高于对照组（92.00% vs 74.00%），差异有统计学意义（P＜0.05）。结论 银杏酮酯分散片治疗冠心病合并高血压具有理想的临床疗效，可有效改善患者血压水平，值得临床应用。
Abstract:
Objective To investigate the clinical efficacy of ginkgo ketone ester dispersible tablets in patients with coronary heart disease complicated with hypertension. Methods 100 patients with coronary heart disease and hypertension who were treated in our hospital from January to December 2018 were randomly divided into the control group and the study group, 50 cases each. The control group was treated with amlodipine besylate + Irbesartan combined with compound Danshen tablets, the study group was treated with amlodipine besylate + irbesartan combined with ginkgo ketone ester dispersible tablets, comparing the two groups before treatment, treatment for 8 weeks, 3 months, 6 months After the blood pressure level and clinical efficacy. Results After 8 weeks of treatment, the blood pressure of both groups decreased compared with that before treatment, and the improvement of the study group was better than that of the control group,the difference was statistically significant (P<0.05). After 3 months and 6 months of treatment, the blood pressure level of the study group remained stable. The blood pressure level of the control group showed an increasing trend. The blood pressure level of the study group was lower than that of the control group,the difference was statistically significant (P<0.05). The total effective rate of the study group was higher than that of the control group (92.00% vs 74.00%), the difference was statistically significant (P<0.05). Conclusion Ginkgo ketone ester dispersible tablets have an ideal clinical effect in the treatment of coronary heart disease complicated with hypertension, which can effectively improve the blood pressure level of patients, and it's the worthy of clinical application.

参考文献/References:

[1]Rui L,Wenjing H,Xiaoqiang L,et al.Association of circulating BMP9 with coronary heart disease and hypertension in Chinese populations[J].BMC Cardiovascular Disorders,2019,19(1):23-26. [2]俞建,胡文志.银杏酮酯分散片对冠心病稳定性心绞痛氧化应激的影响[J].天津中医药,2017,34(2):103-105. [3]陈志华,张梅,李镒冲.我国成年人血压水平与心脑血管疾病行为危险因素及其聚集关系分析[J].中华流行病学杂志,2018,39(5):640-645. [4]张永创.银杏酮酯分散片治疗冠心病疗效观察[J].中西医结合心血管病电子杂志,2018,6(31):149. [5]曹书芳.吲达帕胺联合氨氯地平治疗高血压合并冠心病患者的临床疗效及其对血脂水平的影响[J].黑龙江医药,2018,31(2): 285-286. [6]任黔玲,周溯,马良金,等.银杏酮酯滴丸与苯磺酸左旋氨氯地平和厄贝沙坦用于治疗老年高血压的疗效和安全性[J].西部医学,2018,30(5):129-132. [7]黄晓钢.中西医结合治疗冠心病合并高血压的疗效及对心功能的影响[J].临床医药文献电子杂志,2018,5(77):78,85. [8]杨涛,尹晓新,朝浩.银杏酮酯分散片联合前列地尔注射液治疗缺血性脑卒中的临床研究[J].山西医药杂志,2017,46(16):1965-1968. [9]纪红,潘美妍,王丹.银杏酮酯分散片对缺血性脑卒中NIHSS评分、血脂水平变化及临床疗效研究[J].陕西医学杂志,2018(6):1568-1572. [10]俞建,胡文志.银杏酮酯分散片对冠心病稳定性心绞痛氧化应激的影响[J].天津中医药,2017,34(2):103-105.

更新日期/Last Update: 2019-11-01