[1]俞 越,任 静,文荟媛,等.阿普唑仑治疗BPPV患者复位后睡眠及情绪障碍的疗效[J].医学信息,2019,32(24):40-42.[doi:10.3969/j.issn.1006-1959.2019.24.013]
　YU Yue,REN Jing,WEN Hui-yuan,et al.The Efficacy of Alprazolam in the Treatment of Sleep and Mood Disorders in Patients with BPPV after Reduction[J].Medical Information,2019,32(24):40-42.[doi:10.3969/j.issn.1006-1959.2019.24.013]
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阿普唑仑治疗BPPV患者复位后睡眠及情绪障碍的疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年24期
页码:
40-42
栏目:
论著
出版日期:
2019-12-15

文章信息/Info

Title:
The Efficacy of Alprazolam in the Treatment of Sleep and Mood Disorders in Patients with BPPV after Reduction
文章编号:
1006-1959（2019）24-0040-03
作者:
俞 越; 任 静; 文荟媛; 祝东林
（南京医科大学附属脑科医院神经内科，江苏 南京 210029）
Author(s):
YU Yue; REN Jing; WEN Hui-yuan; ZHU Dong-lin
(Department of Neurology,Brain Hospital Affiliated to Nanjing Medical University,Nanjing 210029,Jiangsu,China)
关键词:
良性阵发性位置性眩晕; 手法复位; 阿普唑仑; 睡眠质量; 焦虑
Keywords:
Benign paroxysmal positional vertigo; Manual reduction; Alprazolam; Sleep quality;  Anxiety
分类号:
R764.33
DOI:
10.3969/j.issn.1006-1959.2019.24.013
文献标志码:
A
摘要:
目的 探讨阿普唑仑对良性阵发性位置性眩晕（BPPV）患者睡眠及情绪障碍的疗效。方法 选取2019年1月~8月我院收治的BPPV患者50例作为研究对象，采用随机数字表法分为对照组22例和试验组28例。对照组接受手法复位+心理支持治疗，试验组在对照组基础上加用小剂量阿普唑仑治疗，比较两组复位后残余头晕及症状再发情况、治疗前后眩晕残障程度、PSQI评分、HAMA评分、HAMD评分及不良反应情况。结果 治疗后，对照组复位后残余头晕及症状再发占比高于试验组，差异有统计学意义（P＜0.05）。试验组DHI总分、功能评分、情绪评分低于对照组，差异有统计学意义（P＜0.05）；两组生理评分比较，差异无统计学意义（P＞0.05）。试验组PSQI、HAMA评分低于对照组，差异有统计学意义（P＜0.05）；两组HAMD评分比较，差异无统计学意义（P＞0.05）。两组各有1例出现轻度可耐受的日间睡眠增多。结论 小剂量阿普唑仑可有效改善BPPV患者复位后残余头晕、睡眠障碍、焦虑抑郁情绪等症状，提高患者的生活质量，降低眩晕复发风险，可作为BPPV患者尤其是顽固性或复发性BPPV患者的推荐方案。
Abstract:
Objective To investigate the efficacy of alprazolam on sleep and mood disorders in patients with benign paroxysmal positional vertigo (BPPV). Methods 50 patients with BPPV treated in our hospital from January to August 2019 were selected as the research objects, and the random number table method was used to divide them into 22 cases in the control group and 28 cases in the test group. The control group received manual reduction and psychological support treatment. The experimental group was treated with low-dose alprazolam on the basis of the control group.The residual dizziness and recurrence of symptoms, the degree of dizziness and disability before and after treatment, PSQI score, HAMA score, and HAMD score and adverse reactions were compared between the two groups. Results After treatment, the proportion of residual dizziness and recurrence of symptoms after reduction in the control group was higher than that in the test group,the difference was statistically significant (P<0.05). The DHI total score, functional score, and emotional score of the experimental group were lower than those of the control group,the differences were statistically significant (P<0.05); there was no significant difference in the physiological scores of the two groups (P>0.05). The PSQI and HAMA scores in the experimental group were lower than those in the control group,the differences were statistically significant (P<0.05). There was no significant difference in the HAMD scores between the two groups (P>0.05).Each group had 1 case of mild-tolerable daytime sleep increased.Conclusion Low-dose alprazolam can effectively improve the symptoms of residual dizziness, sleep disturbance, anxiety and depression after resetting in BPPV patients, improve the quality of life of patients, and reduce the risk of dizziness recurrence recommended solution.

参考文献/References:

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更新日期/Last Update: 2019-12-15