[1]张文兵,袁 波,李忠波.雾化吸入盐酸氨溴索辅助治疗小儿肺炎的效果[J].医学信息,2019,32(24):155-156.[doi:10.3969/j.issn.1006-1959.2019.24.056]
　ZHANG Wen-bing,YUAN Bo,LI Zhong-bo.Effect of Nebulized Inhaled Ambroxol Hydrochloride on Infantile Pneumonia[J].Medical Information,2019,32(24):155-156.[doi:10.3969/j.issn.1006-1959.2019.24.056]
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雾化吸入盐酸氨溴索辅助治疗小儿肺炎的效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年24期
页码:
155-156
栏目:
药物与临床
出版日期:
2019-12-15

文章信息/Info

Title:
Effect of Nebulized Inhaled Ambroxol Hydrochloride on Infantile Pneumonia
文章编号:
1006-1959（2019）24-0155-02
作者:
张文兵; 袁 波; 李忠波
（江西省上栗县人民医院儿科，江西 上栗 337009）
Author(s):
ZHANG Wen-bing; YUAN Bo; LI Zhong-bo
(Department of Pediatrics,People’s Hospital of Shangli County,Shangli 337009,Jiangxi,China)
关键词:
雾化治疗; 盐酸氨溴; 小儿肺炎
Keywords:
Nebulization therapy; Ambroxine hydrochloride; Infantile pneumonia
分类号:
R725.6
DOI:
10.3969/j.issn.1006-1959.2019.24.056
文献标志码:
A
摘要:
目的 观察雾化吸入盐酸氨溴索辅助治疗小儿肺炎的临床效果。方法 选择2017年1月~2019年1月在我院儿科治疗的40例小儿肺炎临床资料，采用随机数字表法分为对照组和观察组，各20例。对照组采用常规治疗，观察组在对照组基础上采用雾化吸入盐酸氨溴索治疗，比较两组临床治疗总有效率、临床症状（咳嗽、肺部湿啰音、体温、呼吸频率）恢复时间、平均住院时间、动脉血气指标[二氧化碳分压（PaCO2）、动脉血氧分压（PaO2）]以及临床不良反应发生情况。结果 观察组治疗总有效率为95.00%，高于对照组的80.00%（P＜0.05）；观察组咳嗽消失、肺部湿啰音消失、体温恢复、呼吸频率恢复时间、平均住院时间均短于对照组（P＜0.05）；观察组治疗后PaCO2水平低于对照组，PaO2水平高于对照组（P＜0.05）；观察组不良反应发生率（5.00%）与对照组（15.00%）比较，差异无统计学意义（P＞0.05）。结论 雾化吸入盐酸氨溴索辅助治疗小儿肺炎效果确切，可提高临床治疗总有效率，且可在短时间内促进临床症状消退，改善动脉血气指标，同时临床不良反应少，治疗安全有效。
Abstract:
Objective To observe the clinical effect of aerosol inhalation of ambroxol hydrochloride in the treatment of infantile pneumonia. Methods The clinical data of 40 children with pneumonia treated in our pediatric department from January 2017 to January 2019 were selected, and they were divided into control group and observation group by random number table method, with 20 cases in each group. The control group was treated with conventional treatment, and the observation group was treated with aerosol inhaled ambroxol hydrochloride on the basis of the control group. The total effective rate and clinical symptoms (cough, wet lung noise, body temperature, and respiratory rate) of the two groups were compared. Mean length of stay, arterial blood gas index [partial carbon dioxide pressure (PaCO2), partial arterial oxygen pressure (PaO2)], and the occurrence of clinical adverse reactions. Results The total effective rate of treatment in the observation group was 95.00%, which was higher than 80.00% in the control group(P<0.05); cough disappeared, wet lungs disappeared in the observation group, body temperature recovered, respiratory frequency recovered, and average The length of hospital stay was shorter than the control group (P<0.05); PaCO2 level in the observation group was lower than that in the control group, and PaO2 level was higher than the control group(P＜0.05); There was no significant difference in the incidence of adverse reactions (5.00%) compared with the control group (15.00%) (P>0.05).Conclusion Aerosol inhalation of ambroxol hydrochloride is an effective adjuvant treatment for infantile pneumonia, which can improve the total effective rate of clinical treatment, and can promote the resolution of clinical symptoms and improve arterial blood gas index in a short time,At the same time, there are few clinical adverse reactions, and the treatment is safe and effective.

参考文献/References:

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更新日期/Last Update: 2019-12-15