[1]李国明.降钙素原、乳酸及C反应蛋白在重症肺炎中的变化及意义[J].医学信息,2020,33(02):70-72.[doi:10.3969/j.issn.1006-1959.2020.02.019]
　LI Guo-ming.Changes and Significance of Procalcitonin, Lactic Acid and C-reactive Protein in Severe Pneumonia[J].Medical Information,2020,33(02):70-72.[doi:10.3969/j.issn.1006-1959.2020.02.019]
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降钙素原、乳酸及C反应蛋白在重症肺炎中的变化及意义()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年02期
页码:
70-72
栏目:
论著
出版日期:
2020-01-15

文章信息/Info

Title:
Changes and Significance of Procalcitonin, Lactic Acid and C-reactive Protein in Severe Pneumonia
文章编号:
1006-1959（2020）02-0070-03
作者:
李国明
（江门市中心医院急诊科，广东 江门 529030）
Author(s):
LI Guo-ming
(Department of Emergency,Jiangmen Central Hospital,Jiangmen 529030,Guangdong,China)
关键词:
降钙素原; 乳酸; C-反应蛋白; APACHE-Ⅱ评分; 重症肺炎
Keywords:
rocalcitonin; Lactic acid; C-reactive protein; APACHE-Ⅱ score; Severe pneumonia
分类号:
R563.1
DOI:
10.3969/j.issn.1006-1959.2020.02.019
文献标志码:
A
摘要:
目的 分析不同时间重症肺炎（SP）患者降钙素原（PCT）、乳酸（Lac）和C-反应蛋白（CRP）水平的变化及其意义。方法 选择2016年1月~2018年12月我院收治的67例SP患者，分别在患者入院后的第1、3、7天以及好转出科或死亡前检测PCT、Lac及CRP水平，同时行APACHE-Ⅱ评分。根据患者预后情况分为存活组（48例）和死亡组（19例）。比较两组不同时间血清PCT、Lac、CRP水平及其与APACHE-Ⅱ评分的相关性。结果 存活组第3、7天以及好转出科前PCT、Lac、CRP、APACHE-Ⅱ评分均低于第1天（P＜0.05）；死亡组第3、7天以及死亡前PCT、Lac、CRP、APACHE-Ⅱ评分均高于第1天（P＜0.05）；死亡组不同时间PCT、Lac、CRP、APACHE-Ⅱ评分均高于存活组（P＜0.05）。重症肺炎患者血清PCT、Lac、CRP与APACHE-Ⅱ评分呈正相关（r＝0.721、0.613、0.814，P＜0.05）。结论 PCT、Lac、CRP与SP的病情程度有关，病情越严重，血清水平越高；动态监测PCT、Lac、CRP及APACHE-Ⅱ评分有助于病情和预后的判断。
Abstract:
Objective To analyze the changes of procalcitonin (PCT),lactic acid (Lac) and C-reactive protein (CRP) levels in patients with severe pneumonia (SP) at different times and their significance.Methods A total of 67 patients with SP who were admitted to our hospital from January 2016 to December 2018 were selected.PCT,Lac,and CRP levels were measured on the 1,3,and 7 days after admission,and before they were discharged from the department or died.At the same time,APACHE-Ⅱ score was performed.According to the prognosis of patients,they were divided into survival group (48 cases) and death group (19 cases).The serum PCT,Lac,CRP levels and their correlation with APACHE-Ⅱ score were compared between the two groups at different times.Results The PCT,Lac,CRP,and APACHE-Ⅱ scores of patients in the survival group on the 3rd and 7th days and before the transfer were lower than those on the 1st day (P＜0.05)；The PCT,Lac,CRP,and APACHE-Ⅱ scores of patients in the death group on the third and seventh days and before death were higher than those on the first day (P＜0.05);the PCT,Lac,CRP,and APACHE-Ⅱ scores of the death group were high at different times In the survival group (P＜0.05).There was a positive correlation between serum PCT,Lac and CRP and APACHE-Ⅱ scores in patients with severe pneumonia (r=0.721,0.613,0.814,P＜0.05).Conclusion PCT,Lac,and CRP are related to the severity of SP.The more severe the disease,the higher the serum level.Dynamic monitoring of PCT,Lac,CRP,and APACHE-Ⅱ scores is helpful to judge the disease and prognosis.

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更新日期/Last Update: 2020-01-15