[1]杨 柳,黄长江,王名雪.癌症的基因治疗研究进展[J].医学信息,2020,33(03):1-5.[doi:10.3969/j.issn.1006-1959.2020.03.001]
 YANG Liu,HUANG Chang-jiang,WANG Ming-xue.Advances in Gene Therapy for Cancer[J].Medical Information,2020,33(03):1-5.[doi:10.3969/j.issn.1006-1959.2020.03.001]
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癌症的基因治疗研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年03期
页码:
1-5
栏目:
出版日期:
2020-02-01

文章信息/Info

Title:
Advances in Gene Therapy for Cancer
文章编号:
1006-1959(2020)03-0001-05
作者:
杨 柳黄长江王名雪
(烟台迈百瑞国际生物医药有限公司,山东 烟台 264006)
Author(s):
YANG LiuHUANG Chang-jiangWANG Ming-xue
(Yantai Maibairui International Biomedicine Co.,Ltd.,Yantai 264006,Shandong,China)
关键词:
基因治疗癌症自杀基因基因沉默抑癌基因免疫疗法抗血管生成
Keywords:
Gene therapyCancerSuicide geneGene silencingTumor suppressor geneImmunotherapyAnti-angiogenesis
分类号:
R730.59
DOI:
10.3969/j.issn.1006-1959.2020.03.001
文献标志码:
A
摘要:
癌症的基因治疗是利用载体通过转基因技术将外源基因转入病患体内,以沉默致病基因、修改突变基因、抑制癌细胞生长、提高癌症药敏性等手段治疗癌症患者。本文对目前癌症基因治疗最常用的五种技术,即自杀基因疗法、基因沉默疗法、抑癌基因疗法、免疫系统疗法和抗血管生成基因疗法进行综述,并分析基因治疗的应用价值和目前存在的安全性问题,以期对相关研究提供一定的参考。
Abstract:
Gene therapy for cancer is the use of vectors to transfer foreign genes into patients through transgenic technology, and to silence cancer-causing genes, modify mutant genes, inhibit cancer cell growth, and improve cancer drug sensitivity. This article reviews the five most commonly used techniques for cancer gene therapy, namely suicide gene therapy, gene silencing therapy, tumor suppressor gene therapy, immune system therapy, and anti-angiogenic gene therapy,and security issues in order to provide some reference for related research.

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更新日期/Last Update: 2020-02-01