[1]陶 源,徐俊林,张春铭,等.基于数据挖掘《中医方剂大辞典》中治疗噎膈的用药规律[J].医学信息,2020,33(05):22-24.[doi:10.3969/j.issn.1006-1959.2020.05.007]
　TAO Yuan,XU Jun-lin,ZHANG Chun-ming,et al.Based on the Data Mining 《Dictionary of Traditional Chinese Medicine Prescriptions》 in the Treatment of Achalasia of Cardia Medication Rules[J].Medical Information,2020,33(05):22-24.[doi:10.3969/j.issn.1006-1959.2020.05.007]
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基于数据挖掘《中医方剂大辞典》中治疗噎膈的用药规律()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年05期
页码:
22-24
栏目:
出版日期:
2020-03-01

文章信息/Info

Title:
Based on the Data Mining 《Dictionary of Traditional Chinese Medicine Prescriptions》 in the Treatment of Achalasia of Cardia Medication Rules
文章编号:
1006-1959（2020）05-0022-03
作者:
陶 源; 徐俊林; 张春铭; 等
（北京市昌平区中医医院脾胃病科，北京 100091）
Author(s):
TAO Yuan; XU Jun-lin; ZHANG Chun-ming; et al
(Department of Spleen and Gastroenterology,Changping District Traditional Chinese Medicine Hospital,Beijing 100091,China)
关键词:
噎膈; 数据挖掘; 用药规律
Keywords:
Achalasia of cardia; Data mining; Medication rules
分类号:
R256.32
DOI:
10.3969/j.issn.1006-1959.2020.05.007
文献标志码:
B
摘要:
目的 分析《中医方剂大辞典》中治疗噎膈的用药规律。方法 基于古今医案云平台（V2.1）对《中医方剂大辞典》中514首治疗噎膈的方剂进行系统集成的数据挖掘，通过统计单味药频次、药性药味归经功效、药对的关联规则、聚类情况，总结治疗噎膈的临床用药规律。结果 514首噎膈方中，涉及中药450味，单味药频次排名前5的分别为陈皮、木香、肉桂、人参、槟榔；药性以温性最多（52.18%），药味以辛最多（38.40%），其次为苦（30.27%）；归经以脾经最多（24.08%），其次为胃经（18.03%），功效以燥湿化痰最多；高频药物组合排名前5的分别为“肉桂-陈皮” “肉桂-木香” “木香-陈皮” “槟榔-木香” “白术-陈皮”。药物聚类共4类：第一类：陈皮、甘草、炙甘草；第二类：木香、槟榔、丁香、豆蔻、青皮；第三类：生姜、肉桂、诃子、白术、厚朴、人参、茯苓、赤茯苓；第四类：半夏、沉香、当归、砂仁、香附、吴茱萸、炮姜、附子、枳壳、大黄、桔梗、神曲、三棱、莪术。结论 《中医方剂大辞典》中治疗噎膈方剂的组方以温阳行气、健脾化痰药居多，根据药物聚类共有4类，其中陈皮、甘草为治疗噎膈的核心药物，药性当以温性药为主，药味以辛、苦为主，归经以脾经、胃经为主。
Abstract:
Objective To analyze the medication rules for treating achalasia of cardia in the《Dictionary of Traditional Chinese Medicine Prescriptions》. Methods Based on the ancient and modern medical case cloud platform (V2.1), systematically integrated data mining was performed on 514 prescriptions for treating achalasia of cardia in the 《Dictionary of Traditional Chinese Medicine Prescriptions》. The statistics of the frequency of single-drug medicine, the efficacy of medicinal medicinal flavors, the association rules of drug pairs, and the clustering conditions were used to summarize the clinical rules for the treatment of achalasia of cardia. Results Among the 514 prescriptions, 450 flavors of traditional Chinese medicine are involved. The top 5 of the single-drug frequency are Chenpi, Muxiang, Cinnamon, Ginseng, and Areca.The medicinal properties are most mild (52.18%), the medicinal taste is most astringent (38.40%), followed by bitterness (30.27%); the meridian is the most common spleen meridian (24.08%), followed by the stomach meridian (18.03%), and the effect is dry Wet phlegm is the most; the top 5 high-frequency drug combinations are "Cinnamon-Cinnamon", "Cinnamon-Woody", "Woody-Cinnamon", "Betel Nut-Woody", and "Atractylodes-Central". There are 4 categories of drug clusters: the first category: Chenpi, licorice, and licorice; the second category: woody, betel nut, cloves, cardamom, green peel; the third category: ginger, cinnamon, gardenia, atractylodes, Magnolia, ginseng , Poria, Red Poria; the fourth category: Pinellia oleifera, Agarwood, Angelica, Amomum villosum, Xiangfu, Fructus Corni, Artichoke ginger, Aconite, Currant shell, Rhubarb, Bellflower, Divine Comedy, Sanling, Curcuma. Conclusion The prescriptions for treating achalasia of cardia in the 《Dictionary of Traditional Chinese Medicine Prescriptions》 are mostly Wenyangxingqi, spleen relieving phlegm, and phlegm. There are 4 categories based on drug clustering. Among them, tangerine peel and licorice are the core drugs for achalasia of cardia. Mainly medicinal drugs, the main taste is Xin, bitter, and the main spleen and stomach.

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更新日期/Last Update: 2020-03-01