[1]唐至立,严申云,钟 华.胎儿心脏畸形孕早期超声NT厚度及血流频谱分析[J].医学信息,2020,33(06):168-169.[doi:10.3969/j.issn.1006-1959.2020.06.057]
　s.Analysis of NT Thickness and Blood Flow Spectrum in Early Pregnancy of Fetal Cardiac Malformation[J].Medical Information,2020,33(06):168-169.[doi:10.3969/j.issn.1006-1959.2020.06.057]
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胎儿心脏畸形孕早期超声NT厚度及血流频谱分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年06期
页码:
168-169
栏目:
诊疗技术
出版日期:
2020-03-15

文章信息/Info

Title:
Analysis of NT Thickness and Blood Flow Spectrum in Early Pregnancy of Fetal Cardiac Malformation
文章编号:
1006-1959（2020）06-0168-02
作者:
唐至立; 严申云; 钟 华
（永州市中心医院超声医学科，湖南 永州 425006）
Author(s):
s
(Department of Ultrasound Medicine,Yongzhou Central Hospital,Yongzhou 425006,Hunan,China)
关键词:
胎儿; 心脏畸形; 孕早期; 超声; 颈项透明层; 血流频谱
Keywords:
Fetus; Cardiac malformation; Early pregnancy; Ultrasound; Cervical transparent layer;  Blood flow spectrum
分类号:
R445.1；R714.5
DOI:
10.3969/j.issn.1006-1959.2020.06.057
文献标志码:
A
摘要:
目的 研究胎儿心脏畸形孕早期超声NT厚度及血流频谱分析的应用价值，为临床诊断提供依据。方法 选择2015年1月~2018年1月在永州市中心医院进行产前检查的5000例孕妇作为研究对象。采用美国CE公司生产的E8彩色多普勒超声检测仪对怀孕11~13+6周的孕妇进行检查，与胎儿出生后超声心动图复查结果相互对照，比较胎儿NT增厚、静脉导管血流频谱异常的检测结果对于胎儿心脏畸形诊断的准确性、灵敏度、特异度。结果 胎儿心脏畸形预测方面血流频谱彩色超声检测阳性筛査率为3.44%，阳性预测值为30.23%，特异度为96.56%，阳性预测值为30.23%；NT值增厚阳性筛查率为4.34%，阳性预测值为23.96%，特异度为95.66%，阳性预测值为23.96%；血流频谱及NT值阳性筛查率为0.90%，阳性预测值为66.67%。结论 多普勒超声检查在胎儿心脏畸形的早期筛查中存在一定优势，可根据早期超声NT厚度及血流频谱分析对孕胎儿心脏畸形进行早期的筛查。
Abstract:
Objective To study the application value of ultrasonographic NT thickness and blood flow spectrum analysis in early pregnancy of fetal cardiac malformation, and to provide basis for clinical diagnosis. Methods A total of 5,000 pregnant women who underwent prenatal examination in Yongzhou Central Hospital from January 2015 to January 2018 were selected as the study subjects. The E8 color Doppler ultrasound detector produced by the American CE company was used to check pregnant women from 11 to 13+6 weeks of pregnancy. The results were compared with the results of fetal echocardiography after birth to compare fetal NT thickening and venous catheter blood flow spectrum. The accuracy, sensitivity, and specificity of abnormal detection results for the diagnosis of fetal cardiac malformations. Results In terms of fetal cardiac malformation, the positive screening rate of color ultrasound detection of blood flow spectrum was 3.44%, the positive predictive value was 30.23%, the specificity was 96.56%, and the positive predictive value was 30.23%; the positive screening rate of thickened NT value was 4.34% The positive predictive value was 23.96%, the specificity was 95.66%, and the positive predictive value was 23.96%. The positive screening rate of blood flow spectrum and NT value was 0.90%, and the positive predictive value was 66.67%. Conclusion Doppler ultrasound has some advantages in early screening of fetal heart malformations. Early screening of pregnant fetal heart malformations can be performed based on early ultrasound NT thickness and blood flow spectrum analysis.

参考文献/References:

[1]王银,李谊,钱隽,等.11~13+6周运用二切面法筛查胎儿严重心脏畸形[J].中国超声医学杂志,2019,35(3):284-287.[2]何敏瑜,肖春梅,张晓航,等.产前超声诊断8p三体胎儿复杂心脏畸形1例[J].中国医学影像技术,2018,34(11):1750.[3]丁海耀,周文蓉.二维联合四维超声检查在先天性心脏畸形胎儿产前诊断中的应用[J].山东医药,2016,56(20):63-64.[4]薛林燕,赵旭,刘君,等.超声诊断双胎妊娠之一胎儿Cantrell五联征[J].中国医学影像学杂志,2018,26(2):133-134,139.[5]辛甜甜,席丽丽,赵丽娇,等.单脐动脉胎儿心脏畸形超声筛查的意义[J].上海交通大学学报(医学版),2014,34(5):666-670[6]仇利,罗红.产前超声筛查中孕期胎儿心脏畸形对诊断染色体异常价值的Meta分析[J].中国介入影像与治疗学,2016,13(12):747-752.

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更新日期/Last Update: 2020-03-15