[1]刘婉莹,陈佳琪,杨 帆,等.组蛋白H3赖氨酸位点甲基化修饰对骨骼肌细胞分化的调控作用[J].医学信息,2020,33(07):24-28.[doi:10.3969/j.issn.1006-1959.2020.07.009]
 LIU Wan-ying,CHEN Jia-qi,YANG Fan,et al.Regulation Effect of Methylation Modification of Histone H3 Lysine on Skeletal Muscle Cell Differentiation[J].Medical Information,2020,33(07):24-28.[doi:10.3969/j.issn.1006-1959.2020.07.009]
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组蛋白H3赖氨酸位点甲基化修饰对骨骼肌细胞分化的调控作用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年07期
页码:
24-28
栏目:
综述
出版日期:
2020-04-01

文章信息/Info

Title:
Regulation Effect of Methylation Modification of Histone H3 Lysine on Skeletal Muscle Cell Differentiation
文章编号:
1006-1959(2020)07-0024-05
作者:
刘婉莹陈佳琪杨 帆
(西安医学院临床医学院,陕西 西安 710021)
Author(s):
LIU Wan-yingCHEN Jia-qiYANG Fanet al
(Clinical Medical College of Xi’an Medical College,Xi’an 710021,Shaanxi,China)
关键词:
骨骼肌分化表观遗传组蛋白甲基化
Keywords:
Skeletal muscleDifferentiationEpigeneticHistone methylation
分类号:
R329.1
DOI:
10.3969/j.issn.1006-1959.2020.07.009
文献标志码:
A
摘要:
骨骼肌是人体四大基本组织之一,骨骼肌病变严重影响人体运动功能,甚至危及生命。近年来研究表明组蛋白甲基化修饰与骨骼肌细胞的分化调控及骨骼肌疾病有密切联系。本文就骨骼肌的发生及与组蛋白修饰的关系及组蛋白H3常见位点甲基化修饰对骨骼肌细胞分化的调控作一综述,以期为骨骼肌分化及骨骼肌相关疾病的发病机制及治疗研究提供理论参考。
Abstract:
Skeletal muscle is one of the four basic tissues of the human body. Skeletal muscle lesions seriously affect human motor function and even endanger life. Recent studies have shown that histone methylation modification is closely related to the regulation of skeletal muscle cell differentiation and skeletal muscle diseases. This article reviews the development of skeletal muscle, its relationship with histone modification, and the regulation of histone H3 common site methylation modification on skeletal muscle cell differentiation, with a view to the pathogenesis and treatment of skeletal muscle differentiation and skeletal muscle related diseases research provides theoretical reference.

参考文献/References:

[1]曹志发,孟昭琴,姚为俊.新编运动生理学[M].北京:人民体育出版社,2004:100-101.[2]Giordani LHG,Negroni E,Sakai H,et al.High-Dimensional Single-Cell Cartography Reveals Novel Skeletal Muscle-Resident Cell Populations[J].Mol Cell,2019,74(3):609-621.[3]Cong FJ,Yan L,Xiang BD,et al.lnc133b,a novel,long non-coding RNA,regulates bovine skeletal muscle satellite cell proliferation and differentiation by mediating miR-133b[J].Gene,2017(630):35-43.[4]Wang S,Jin J,Xu Z,et al.Functions and Regulatory Mechanisms of lncRNAs in Skeletal Myogenesis, Muscle Disease and Meat Production[J].Cells,2019,8(9):1107. [5]Qin C,He C,Hanrui Q,et al.Recent advances on the role of long non-coding RNA H19 in regulating mammalian muscle growth and development[J].Hereditas,2017,39(12):1150-1157.[6]Bentzinger CF,Yu XW,Rudnicki MA.Building Muscle:Molecular Regulation of Myogenesis[J].Cold Spring Harbor Perspectives in Biology,2012,4(2):1-16.[7]Buckingham M,Rigby PWJ.Gene Regulatory Networks and Transcriptional Mechanisms that Control Myogenesis[J].Developmental Cell,2014,28(3):225-238.[8]Mal KA.Histone methyltransferase Suv39h1 represses MyoD-stimulated myogenic differentiation[J].Embo Journal,2006,25(14):3323-3334.[9]Bag A,Bag N.Tea Polyphenols and Prevention of Epigenetic Aberrations in Cancer[J].J Nat Sci Biol Med,2018,9(1):2-5.[10]汤其群.生物化学与分子生物学[M].上海:复旦大学出版社,2015:149-157.[11]Paone C,Rudeck S,Etard C,et al.Loss of zebrafish Smyd1a interferes with myofibrillar integrity without triggering the misfolded myosin response[J].Biochemical & Biophysical Research Communications,2018,496(2):339-345.[12]Spadaccini R,Perrin H,Bottomley MJ,et al.RETRACTED:Structure and Functional Analysis of the MYND Domain[J].J Mol Biol,2006,358(2):498-508.[13]Stuelsatz P,Keire P,Yablonka-Reuveni Z.Isolation,Culture,and Immunostaining of Skeletal Muscle Myofibers from Wildtype and Nestin-GFP Mice as a Means to Analyze Satellite Cell[J].Methods of Molecular Biology,2017(1556):51-102.[14]Stewart MD,Lopez S,Nagandla H,et al.Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy,internalization of nuclei and myofibrillar disarray[J].Disease Models & Mechanisms,2016,9(3):347-359.[15]Liu XH,Gasperi RD,Bauman WA,et al.Nandrolone-induced nuclear accumulation of MyoD protein is mediated by Numb,a Notch inhibitor,in C2C12 myoblasts[J].Physiological Reports,2018,6(1):1333-1349.[16]王娟,叶湘漓,姜丽,等.IGF-1通过SRF结合位点调节SMYD1在C2C12细胞中的表达[J].中国生物化学与分子生物学报,2010(12):44-51.[17]Codato R,Perichon M,Divol A,et al.The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network[J].Sci Rep,2019,9(1):1-14.[18]Kwon T,Chang JH,Kwak E,et al.Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet[J].EMBO Journal,2003,22(2):292-303.[19]Tao Y,Neppl RL,Huang ZP,et al.The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly[J].Journal of Cell Biology,2011,194(4):551-565.[20]Blum R,Vethantham V,Bowman C,et al.Genome-wide identification of enhancers in skeletal muscle: the role of MyoD1[J].Genes & Development,2012,26(24):2763-2779.[21]Horton JR,Engstrom A,Zoeller EL,et al.Characterization of a Linked Jumonji Domain of the KDM5/JARID1 Family of Histone H3 Lysine 4 Demethylases[J].Journal of Biological Chemistry,2016,291(6):2631-2646.[22]Schibler A,Koutelou E,Tomida J,et al.Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2[J].Genes & Development,2016,30(10):1187-1197.[23]Lee JE,Wang C,Xu S,et al.H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation[J].Elife,2013,2(2):1-25.[24]戴威.KDM5C与骨肉瘤及骨骼肌再生的关系研究[D].重庆医科大学,2018.[25]Hyun K,Jeon J,Park K,et al.Writing,erasing and reading histone lysine methylations[J].Experimental & Molecular Medicine,2017,49(4):324-345.[26]Li J,Yang G,Liu S,et al.Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients[J].Clinical Epigenetics,2019,11(1):107.[27]Oriane M,Roscoe K,Benoit C,et al.Alternative splicing regulates the expression of G9A and SUV39H2 methyltransferases,and dramatically changes SUV39H2 functions[J].Nucleic Acids Research,2015,43(3):1869-1882.[28]Casciello F,Al-Ejeh F,Kelly G,et al.G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis[J].Proceedings of the National Academy of Sciences,2017,114(27):7077-7082.[29]Rao VK,Rong OJ,Rani SS,et al.G9a promotes proliferation and inhibits cell cycle exit during myogenic differentiation[J].Nucleic Acids Research,2016,44(17):8129-8143.[30]Ait-Si-Ali S,Guasconi V,Fritsch L,et al.A Suv39h-dependent mechanism for silencing S-phase genes in differentiating but not in cycling cells[J].EMBO Journal,2004,23(3):605-615.[31]Wei J,Yangyang S,Jian P,et al.Histone H3 Methyltransferase Suv39h1 Prevents Myogenic Terminal Differentiation by Repressing MEF2 Activity in Muscle Cells[J].International Journal of Molecular Sciences,2016,17(12):1908-1923.[32]Wardle FC.Master control:transcriptional regulation of mammalian Myod[J].Journal of Muscle Research and Cell Motility,2019(40):211-226.[33]Rajabi H,Hiraki M,Tagde A,et al.MUC1-C activates EZH2 expression and function in human cancer cells[J].Scientific Reports,2017,7(1):7481-7493.[34]Collinson A,Collier AJ,Morgan NP,et al.Deletion of the Polycomb-Group Protein EZH2 Leads to Compromised Self-Renewal and Differentiation Defects in Human Embryonic Stem Cells[J].Cell Rep,2016,17(10):2700-2714.[35]Caretti G,Padova MD,Micales B,et al.The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation[J].Genes Dev,2004,18(21):2627-2638.[36]Juan AH,Derfoul A,Feng X,et al.Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells[J].Genes & Development,2011,25(8):789-794.[37]Liu T,Hou L,Zhao Y,et al.Epigenetic silencing of HDAC1 by miR-449a upregulates Runx2 and promotes osteoblast differentiation[J].International Journal of Molecular Medicine,2015,35(1):238-246.[38]Satijn DPE,Hamer KM,den Blaauwen J,et al.The Polycomb Group Protein EED Interacts with YY1,and Both Proteins Induce Neural Tissue in Xenopus Embryos[J].Molecular & Cellular Biology,2001,21(4):1360-1369.[39]李朝夕,黄健,张姝,等.miRNA及其靶基因EZH2在乳腺癌中的表达及临床意义[J].医学研究生学报,2019,(8):833-839.[40]Fan DC,Qi H,Hou JX,et al.Mesenchymal stem cell-derived exosomal microRNA-133b suppresses glioma progression via Wnt/β-catenin signaling pathway by targeting EZH2[J].Stem Cell Res Ther,2019,10(1):1-14.[41]Rodríguez-Carballo E,Lopez-Delisle L,Yakushiji-Kaminatsui N,et al.Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes[J].BMC Biology,2019,17(1):55.[42]Gauchat D,Mazet F,Berney C,et al.Evolution of Antp-class genes and differential expression of Hydra Hox/paraHox genes in anterior patterning[J].Proceedings of the National Academy of Sciences of the United States of America,2000,97(9):4493-4498.[43]Kodaka Y,Tanaka K,Kitajima K,et al.LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2[J].Experimental Cell Research,2015,331(2):309-319.[44]李慧霞,朱晓莉,王敬强.Ezh2与G9a在Msx1抑制成肌细胞分化过程中的协同作用[J].基因组学与应用生物学,2017(6):79-88.[45]Eom GH,Kim KB,Jin HK,et al.Histone Methyltransferase SETD3 Regulates Muscle Differentiation[J].Journal of Biological Chemistry,2011,286(40):34733-34742.[46]Zhao MJ,Xie J,Shu WJ,et al.MiR-15b and miR-322 inhibit SETD3 expression to repress muscle cell differentiation[J].Cell Death and Disease,2019(10):1-13.

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更新日期/Last Update: 2020-04-01