[1]张 磊.肾康注射液联合包醛氧淀粉治疗慢性肾功能衰竭的观察[J].医学信息,2020,33(09):150-151.[doi:10.3969/j.issn.1006-1959.2020.09.050]
　ZHANG Lei.Observation on Treatment of Chronic Renal Failure with Shenkang Injection Combined with Oxyamyli Tectus Aldehydum[J].Medical Information,2020,33(09):150-151.[doi:10.3969/j.issn.1006-1959.2020.09.050]
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肾康注射液联合包醛氧淀粉治疗慢性肾功能衰竭的观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年09期
页码:
150-151
栏目:
中医中药
出版日期:
2020-05-01

文章信息/Info

Title:
Observation on Treatment of Chronic Renal Failure with Shenkang Injection Combined with Oxyamyli Tectus Aldehydum
文章编号:
1006-1959（2020）09-0150-02
作者:
张 磊
（天津市宝坻区人民医院肾内科，天津 301800）
Author(s):
ZHANG Lei
(Department of Nephrology,People’s Hospital of Baodi District,Tianjin 301800,China)
关键词:
肾康注射液; 包醛氧淀粉; 肾功能衰竭
Keywords:
Shenkang injection; Oxyamyli tectus aldehydum; Renal failure
分类号:
R692.5
DOI:
10.3969/j.issn.1006-1959.2020.09.050
文献标志码:
A
摘要:
目的 观察肾康注射液联合包醛氧淀粉治疗慢性肾功能衰竭的临床疗效。方法 选取2018年6月~2019年6月我院诊治的112例慢性肾功能衰竭患者为研究对象，采用随机数字表法分为对照组和观察组，各56例。对照组采用包醛氧淀粉治疗，观察组在对照组基础上联合肾康注射液治疗，比较两组临床治疗总有效率、治疗前后肾功能指标[24h尿蛋白（24h Pro）、尿素氮（BUN）、血肌酐（Scr）]、治疗后临床症状评分及临床不良反应发生情况。结果 观察组临床治疗总有效率94.64%，高于对照组80.36%，差异有统计学意义（P＜0.05）；治疗后两组24h Pro、BUN、Scr均低于治疗前，且观察组低于对照组，差异有统计学意义（P＜0.05）；治疗后观察组恶心呕吐、疲乏、浮肿症状评分均低于对照组，差异有统计学意义（P＜0.05）；观察组临床不良反应发生率（7.14%）与对照组（8.93%）比较，差异无统计学意义（P＞0.05）。结论 慢性肾功能衰竭采用肾康注射液联合包醛氧淀粉治疗疗效确切，有助于缓解临床症状、改善肾功能，且不会增加不良反应，应用安全可靠。
Abstract:
Objective To observe the clinical effect of Shenkang injection combined with oxyamyli tectus aldehydum in the treatment of chronic renal failure.Methods A total of 112 patients with chronic renal failure diagnosed and treated in our hospital from June 2018 to June 2019 were selected as the research object. They were divided into a control group and an observation group with a random number table method, 56 cases each. The control group was treated with oxyamyli tectus aldehydum.The observation group was treated with Shenkang injection on the basis of the control group. The total clinical treatment efficiency, renal function indexes before and after treatment were compared between the two groups[24h urine protein (24h Pro), urea nitrogen (BUN),blood creatinine (Scr)], clinical symptom scores and clinical adverse reactions after treatment.Results The total effective rate of clinical treatment in the observation group was 94.64%, higher than the control group 80.36%, the difference was statistically significant(P<0.05); 24h Pro, BUN, and Scr of the two groups after treatment were lower than before treatment, and the observation group was lower than the control The difference between the two groups was statistically significant (P<0.05); the scores of symptoms of nausea, vomiting, fatigue and edema were lower in the observation group after treatment than the control group,the difference was statistically significant(P<0.05);Compared with the control group (8.93%), the incidence of clinical adverse reactions (7.14%) in the observation group was not statistically significant(P>0.05).Conclusion The treatment of chronic renal failure with Shenkang injection combined with oxyamyli tectus aldehydum has definite curative effect, which can help relieve clinical symptoms and improve renal function without increasing adverse reactions. It is safe and reliable.

参考文献/References:

[1]楚加元.肾康注射液药理及临床研究进展综述[J].现代中药研究与实践,2014,28(2):76-78.[2]邓金华,张奉莲,王定勇,等.肾康注射液治疗慢性肾衰竭的Meta 分析[J].现代药物与临床,2015,30(5):595-599.[3]刘睿．肾康注射液联合血液透析治疗对慢性肾功能衰竭患者肾功能、肾性贫血及细胞因子含量的影响[J]．海南医学院学报,2016,22(20):2386－2389．[4]夏天,肖明．杏丁注射液对慢性肾功能衰竭患者肾小球滤过功能的影响[J]．海南医学,2017,28(20):3381－3383．[5]赵涛,史焱,朱丹,等．肾康注射液治疗慢性肾功能衰竭临床研究[J]．中医学报,2016,31(4):581－583．

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更新日期/Last Update: 2020-05-01