[1]朱郁飞,陈 恳,谢美丽,等.PCT、ALB预测急性胰腺炎严重程度的价值[J].医学信息,2020,(11):163-165.[doi:10.3969/j.issn.1006-1959.2020.11.053]
 ZHU Yu-fei,CHEN Ken,XIE Mei-li,et al.The Value of PCT and ALB in Predicting the Severity of Acute Pancreatitis[J].Medical Information,2020,(11):163-165.[doi:10.3969/j.issn.1006-1959.2020.11.053]
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PCT、ALB预测急性胰腺炎严重程度的价值()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2020年11期
页码:
163-165
栏目:
诊疗技术
出版日期:
2020-06-01

文章信息/Info

Title:
The Value of PCT and ALB in Predicting the Severity of Acute Pancreatitis
文章编号:
1006-1959(2020)11-0163-03
作者:
朱郁飞陈 恳谢美丽
(如皋市人民医院消化科,江苏 如皋 226000)
Author(s):
ZHU Yu-feiCHEN KenXIE Mei-liet al
(Department of Gastroenterology,Rugao People’s Hospital,Rugao 226000,Jiangsu,China)
关键词:
PCTALB胰腺炎
Keywords:
PCTALBPancreatitis
分类号:
R576
DOI:
10.3969/j.issn.1006-1959.2020.11.053
文献标志码:
A
摘要:
目的 探讨降钙素原(PCT)和白蛋白(ALB)预测急性胰腺炎(AP)严重程度的价值。方法 选取2018年5月~2019年9月我院收治的急性胰腺炎患者70例作为研究对象,依据病情严重程度分为重症(SAP)组38例,轻型(MAP)组32例。分别检测血清PCT、ALB水平,用受试者工作特征曲线(ROC曲线)评价PCT、ALB对SAP的诊断效能。结果 SAP组PCT水平高于MAP组(P<0.05);SAP组血清ALB测定值低于MAP组(P<0.05)。以PCT 0.50 ng/ml为界值,其判断SAP的敏感性、特异性为92.10%、81.25%,阳性预测值、阴性预测值为82.93%、86.67%,阳性似然比、阴性似然比为4.77、0.13,准确性为94.60%,约登指数为0.73。以ALB 36 g/L为界值,其判断SAP的敏感性81.58%、特异性87.50% ,阳性预测值、阴性预测值为88.57%、80.00% ,阳性似然比、阴性似然比6.52、0.21,准确性为87.90%,约登指数为0.66。血清PCT与ALB呈负相关(r=-0.378,P<0.01)。两者联合检测其敏感性为86.80%、特异性为93.80%、准确性为97.10%。结论 血清PCT、ALB的活性测定均有助于预测急性胰腺炎严重程度,两者联合检测可提高预测诊断的特异性和准确性。
Abstract:
Objective To explore the value of procalcitonin (PCT) and albumin (ALB) in predicting the severity of acute pancreatitis (AP). Methods A total of 70 patients with acute pancreatitis admitted to our hospital from May 2018 to September 2019 were selected as the research object, and they were divided into 38 cases in the severe (SAP) group and 32 cases in the mild (MAP) group according to the severity of the disease. Serum PCT and ALB levels were detected, and the receiver operating characteristic curve (ROC curve) was used to evaluate the diagnostic efficacy of PCT and ALB for SAP.Results The PCT level of SAP group was higher than that of MAP group(P<0.05); the serum albumin measurement value of SAP group was lower than that of MAP group(P<0.05). Taking PCT 0.50 ng/ml as the cut-off value, the sensitivity and specificity of SAP are 92.10% and 81.25%.The positive and negative predictive values were 82.93% and 86.67%, the positive and negative likelihood ratios were 4.77 and 0.13, the accuracy was 94.60%, and the Youden index was 0.73. Using ALB 36 g/L as the cut-off value, the sensitivity of SAP is 81.58%, the specificity is 87.50%, the positive predictive value and negative predictive value are 88.57%, 80.0%, positive likelihood ratio, negative likelihood ratio 6.52, 0.21,the accuracy is 87.90%, and the Youden index is 0.66. Serum PCT was negatively correlated with ALB (r=-0.378, P<0.01). The combined detection of the two has a sensitivity of 86.80%, a specificity of 93.80%, and an accuracy of 97.10%.Conclusion Serum PCT and ALB activity measurements are helpful for predicting the severity of acute pancreatitis. The combined detection of the two can improve the specificity and accuracy of predictive diagnosis.

参考文献/References:

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更新日期/Last Update: 1900-01-01