[1]张宗艳,赵 晖,高 超,等.胺碘酮联合琥珀酸美托洛尔缓释片急诊治疗室性心律失常的疗效[J].医学信息,2020,33(19):145-146.[doi:10.3969/j.issn.1006-1959.2020.19.045]
　ZHANG Zong-yan,ZHAO Hui,GAO Chao,et al.Efficacy of Amiodarone Combined with Metoprolol Succinate Sustained-release Tablets in Emergency Treatment of Ventricular Arrhythmia[J].Medical Information,2020,33(19):145-146.[doi:10.3969/j.issn.1006-1959.2020.19.045]
点击复制

胺碘酮联合琥珀酸美托洛尔缓释片急诊治疗室性心律失常的疗效()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年19期
页码:
145-146
栏目:
药物与临床
出版日期:
2020-10-01

文章信息/Info

Title:
Efficacy of Amiodarone Combined with Metoprolol Succinate Sustained-release Tablets in Emergency Treatment of Ventricular Arrhythmia
文章编号:
1006-1959（2020）19-0145-02
作者:
张宗艳; 赵 晖; 高 超; 王贵荣
天津市滨海新区大港医院急诊科，天津 300270
Author(s):
ZHANG Zong-yan; ZHAO Hui; GAO Chao; WANG Gui-rong
Emergency Department,Dagang Hospital,Binhai New Area,Tianjin 300270,China
关键词:
胺碘酮; 琥珀酸美托洛尔; 急诊; 室性心律失常
Keywords:
Amiodarone; Metoprolol succinate; Emergency department; Ventricular arrhythmia
分类号:
R541.7+3
DOI:
10.3969/j.issn.1006-1959.2020.19.045
文献标志码:
A
摘要:
目的 观察胺碘酮联合琥珀酸美托洛尔缓释片急诊治疗室性心律失常的疗效。方法 选取2018年2月~2019年12月我院急诊接诊的150例室性心律失常患者为研究对象，采用随机数字表法分为对照组和观察组，各75例。对照组采用酒石酸美托洛尔缓释片治疗，观察组在对照组基础上采用胺碘酮注射液治疗，比较两组临床治疗总有效率、治疗前后心率、心功能改善情况及临床不良反应发生情况。结果 观察组临床治疗总有效率为94.67%，高于对照组的81.33%，差异有统计学意义（P＜0.05）；治疗后两组心率均低于治疗前，且观察组低于对照组，差异有统计学意义（P＜0.05）；观察组心功能分级Ⅰ级所占比例高于对照组，Ⅱ级、Ⅲ级均低于对照组，差异有统计学意义（P＜0.05）；观察组临床不良反应发生率与对照组比较，差异无统计学意义（P＞0.05）。结论 胺碘酮联合琥珀酸美托洛尔缓释片急诊治疗室性心律失常的疗效确切，总有效率高，有助于改善患者心功能，且临床不良反应少，应用安全。
Abstract:
Objective To observe the efficacy of amiodarone combined with metoprolol succinate sustained-release tablets in emergency treatment of ventricular arrhythmia.Methods A total of 150 patients with ventricular arrhythmia admitted to the emergency department of our hospital from February 2018 to December 2019 were selected as the research objects. They were divided into the control group and the observation group by random number table method, with 75 cases in each group. The control group was treated with metoprolol tartrate sustained-release tablets, and the observation group was treated with amiodarone injection on the basis of the control group. The total effective rates of clinical treatment, heart rate, heart function improvement before and after treatment, and clinical adverse reactions were compared between the two groups.Results The total effective rate of clinical treatment in the observation group was 94.67%, which was higher than 81.33% in the control group,the difference was statistically significant (P<0.05);After treatment, the heart rates of the two groups were lower than before treatment, and the observation group was lower than the control group, the difference was statistically significant (P＜0.05); the proportion of the observation group’s heart function classification I was higher than that of the control group, II and III all were lower than the control group, the difference was statistically significant (P<0.05); the observation group had no significant difference in the incidence of clinical adverse reactions compared with the control group (P>0.05).Conclusion Amiodarone combined with metoprolol succinate sustained-release tablets was effective in emergency treatment of ventricular arrhythmia, with high total effective rate, which helped to improve the heart function of patients, and had few clinical adverse reactions and safe application.

参考文献/References:

[1]郭宁.普罗帕酮与胺碘酮治疗阵发性室上性心律失常的临床研究[J].山西医药杂志,2018,47(3):259-261. [2]杨改宁.胺碘酮与门冬氨酸钾镁联合治疗慢性心力衰竭并室性心律失常45例疗效观察[J].陕西医学杂志,2017,46(11):1594-1595. [3]冯治宽,王恒亮,杨宁.稳心颗粒联合胺碘酮治疗冠心病室性心律失常疗效观察[J].陕西中医,2017,38(7):857-858. [4]郑俊华,唐浩然,景丽英,等.老年室性心律失常患者应用艾司洛尔与胺碘酮联合治疗的临床效果分析[J].中国医学前沿杂志,2014,6(7):31-33. [5]郗昆.胺碘酮联合益气复脉注射液治疗慢性心力衰竭合并室性心律失常的临床效果分析[J].中国当代医药,2015,22(26):161-162,165.

相似文献/References:

[1]冯彩云.胺碘酮导致间质性肺病患者的1例分析[J].医学信息,2018,31(10):191.[doi:10.3969/j.issn.1006-1959.2018.10.068]
[2]何玲玲,程淑芬.曲美他嗪联合琥珀酸美托洛尔治疗冠心病心力衰竭疗效观察[J].医学信息,2018,31(13):142.[doi:10.3969/j.issn.1006-1959.2018.13.042]
　HE Ling-ling,CHENG Shu-fen.Therapeutic Effect of Trimetazidine Combined with Metoprolol Succinate in the Treatment of Coronary Heart Disease with Heart Failure[J].Medical Information,2018,31(19):142.[doi:10.3969/j.issn.1006-1959.2018.13.042]
[3]陶春艳.柔性护理在胺碘酮治疗心房颤动护理中的应用研究[J].医学信息,2018,31(24):154.[doi:10.3969/j.issn.1006-1959.2018.24.046]
　TAO Chun-yan.Application of Flexible Nursing in the Treatment of Atrial Fibrillation with Amiodarone[J].Medical Information,2018,31(19):154.[doi:10.3969/j.issn.1006-1959.2018.24.046]
[4]李杰华.急诊应用胺碘酮联合门冬氨酸钾镁治疗冠心病快速心律失常的疗效[J].医学信息,2020,33(05):154.[doi:10.3969/j.issn.1006-1959.2020.05.050]
　LI Jie-hua.Treatment of Rapid Arrhythmia in Coronary Heart Disease with Amiodarone Combined with Potassium Magnesium Aspartate[J].Medical Information,2020,33(19):154.[doi:10.3969/j.issn.1006-1959.2020.05.050]
[5]李春生.倍他乐克联合胺碘酮治疗阵发性房颤的疗效及对尿酸、SIRT1水平的影响[J].医学信息,2022,35(18):87.[doi:10.3969/j.issn.1006-1959.2022.18.022]
　LI Chun-sheng.Efficacy of Betaloc Combined with Amiodarone in the Treatment of Paroxysmal Atrial Fibrillation and its Effect on Uric Acid and SIRT1 Levels[J].Medical Information,2022,35(19):87.[doi:10.3969/j.issn.1006-1959.2022.18.022]
[6]孙 健.小剂量胺碘酮与美托洛尔治疗老年性房颤的效果及对左心房和心功能的影响[J].医学信息,2022,35(18):105.[doi:10.3969/j.issn.1006-1959.2022.18.028]
　SUN Jian.The Effect of Low-dose Amiodarone and Metoprolol in the Treatment of Senile Atrial Fibrillation and its Effect on Left Atrial and Cardiac Function[J].Medical Information,2022,35(19):105.[doi:10.3969/j.issn.1006-1959.2022.18.028]
[7]李知生.胺碘酮联合利多卡因治疗急性心梗伴室性心律失常的临床疗效[J].医学信息,2020,33(11):149.[doi:10.3969/j.issn.1006-1959.2020.11.048]
　LI Zhi-sheng.Amiodarone Combined with Lidocaine in the Treatment of Acute Myocardial Infarction with Ventricular Arrhythmia[J].Medical Information,2020,33(19):149.[doi:10.3969/j.issn.1006-1959.2020.11.048]
[8]蒲军亮,张 婷.沙库巴曲缬沙坦钠片联合琥珀酸美托洛尔缓释片治疗慢性心力衰竭的疗效观察[J].医学信息,2020,33(14):159.[doi:10.3969/j.issn.1006-1959.2020.14.051]
　PU Jun-liang,ZHANG Ting.Observation of Sacubitril Valsartan Sodium Tablets Combined with Metoprolol Succinate Sustained-release Tablets in the Treatment of Chronic Heart Failure[J].Medical Information,2020,33(19):159.[doi:10.3969/j.issn.1006-1959.2020.14.051]
[9]蔺洪萌.胺碘酮联合西地兰治疗冠心病合并心律失常的疗效[J].医学信息,2021,34(20):161.[doi:10.3969/j.issn.1006-1959.2021.20.043]
　LIN Hong-meng.Effect of Amiodarone Combined with Cedilanid on Coronary Heart Disease Complicated with Arrhythmia[J].Medical Information,2021,34(19):161.[doi:10.3969/j.issn.1006-1959.2021.20.043]

更新日期/Last Update: 1900-01-01