[1]郝亚柯,李学智.盐酸米诺环素与碘合剂治疗种植体周围炎患者的疗效比较[J].医学信息,2020,33(23):144-146.[doi:10.3969/j.issn.1006-1959.2020.23.042]
　HAO Ya-ke,LI Xue-zhi.Comparison of Therapeutic Effects of Minocycline Hydrochloride and Iodine Mixture on Peri-implant Inflammation[J].Medical Information,2020,33(23):144-146.[doi:10.3969/j.issn.1006-1959.2020.23.042]
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盐酸米诺环素与碘合剂治疗种植体周围炎患者的疗效比较()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年23期
页码:
144-146
栏目:
药物与临床
出版日期:
2020-12-01

文章信息/Info

Title:
Comparison of Therapeutic Effects of Minocycline Hydrochloride and Iodine Mixture on Peri-implant Inflammation
文章编号:
1006-1959（2020）23-0144-03
作者:
郝亚柯; 李学智
（西宁市第一医疗集团总院口腔内科，青海 西宁 810000）
Author(s):
HAO Ya-ke; LI Xue-zhi
(Department of Oral Medicine,General Hospital of Xining First Medical Group,Xining 810000,Qinghai,China)
关键词:
盐酸米诺环素; 碘合剂; 种植体周围炎; 龈沟出血指数; 探诊深度
Keywords:
Minocycline hydrochloride; Iodine mixture; Peri-implantinflammation; Gingival crevicular bleeding index; Probing depth
分类号:
R783
DOI:
10.3969/j.issn.1006-1959.2020.23.042
文献标志码:
A
摘要:
目的 探讨盐酸米诺环素与碘合剂治疗种植体周围炎患者的临床疗效。方法 选择我院2018年1~12月收治的292例种植体周围炎患者作为研究对象，按照随机数字表法分为观察组和对照组，每组146例。对照组采用碘合剂治疗，观察组采用盐酸米诺环素治疗，比较两组治疗前、治疗后1、3、6周PLI、PD及SBI值。结果 两组治疗后1、3周PLI、PD及SBI均较治疗前下降，且观察组低于对照组，差异有统计学意义（P＜0.05）。两组治疗后6周PLI、PD及SBI较治疗后1、3周上升，较治疗前下降，差异有统计学意义（P＜0.05）；但组间比较，差异无统计学差异（P＞0.05）。结论 盐酸米诺环素治疗种植体周围炎临床疗效确切，可有效杀灭致病菌，改善患者PLI、PD、SBI指标，但药物时效性在治疗6周后下降，应每隔3周进行重复治疗，以有效保持药物浓度。
Abstract:
Objective This study aims to explore the clinical effect of minocycline hydrochloride and iodine mixture in the treatment of peri-implant inflammation.Methods 292 patients admitted to our hospital from January 2018 to December 2018 were randomly divided into observation group (n=146) and control group (n=146). The control group was treated with iodine mixture and the observation group with minocycline hydrochloride.The PLI, PD and SBI values of the two groups before treatment, 1, 3, and 6 weeks after treatment were compared.Results The PLI, PD and SBI of the two groups were lower than before the treatment at 1, 3 weeks after treatment, and the observation group was lower than the control group, the difference was statistically significant (P<0.05). The PLI, PD and SBI of the two groups increased at 6 weeks after treatment compared with 1, 3 weeks after treatment, and decreased compared with before treatment,the difference was statistically significant (P<0.05); but there was no statistical difference between the groups (P>0.05).Conclusion Minocycline hydrochloride has a definite clinical effect in the treatment of peri-implantitis. It can effectively kill pathogenic bacteria and improve patients’ PLI, PD, and SBI indicators. However, the time-effectiveness of the drug decreases after 6 weeks of treatment, and the treatment should be repeated every 3 weeks.To effectively maintain drug concentration.

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更新日期/Last Update: 1900-01-01