[1]薛奋龙,王 凯.Micro RNA在心力衰竭中的应用研究[J].医学信息,2021,34(04):35-39.[doi:10.3969/j.issn.1006-1959.2021.04.010]
 XUE Fen-long,WANG Kai.Application of Micro RNA in Heart Failure[J].Medical Information,2021,34(04):35-39.[doi:10.3969/j.issn.1006-1959.2021.04.010]
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Micro RNA在心力衰竭中的应用研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年04期
页码:
35-39
栏目:
综述
出版日期:
2021-02-15

文章信息/Info

Title:
Application of Micro RNA in Heart Failure
文章编号:
1006-1959(2021)04-0035-05
作者:
薛奋龙王 凯
(天津市第一中心医院心血管外科,天津 300192)
Author(s):
XUE Fen-longWANG Kai
(Department of Cardiovascular Surgery,Tianjin First Central Hospital,Tianjin 300192,China)
关键词:
心力衰竭Micro RNA氧化应激
Keywords:
Heart failureMicro RNAOxidative stress
分类号:
R54
DOI:
10.3969/j.issn.1006-1959.2021.04.010
文献标志码:
A
摘要:
心力衰竭是一种复杂的临床综合征,其发生发展涉及免疫与炎症、神经内分泌、氧化应激及心肌纤维化等诸多病理生理过程。Micro RNA是一种高度保守的小RNA,其作为调控关键基因表达的因子直接或间接参与心力衰竭的病理生理过程。近年来Micro RNA在心力衰竭过程中的重要作用得到广泛关注,多种特异Micro RNA可能成为未来诊断心力衰竭的重要标志物,为心力衰竭的诊断治疗提供更好的临床思路。本文就Micro RNA参与心衰的病理发生机制、与心力衰竭生物标志物的关系及其在心力衰竭治疗的应用前景作一综述,以期为临床治疗该疾病提供参考。
Abstract:
Heart failure is a complex clinical syndrome. Its occurrence and development involve many pathophysiological processes such as immunity and inflammation, neuroendocrine, oxidative stress, and myocardial fibrosis.Micro RNA is a highly conserved small RNA, which directly or indirectly participates in the pathophysiological process of heart failure as a factor regulating the expression of key genes.In recent years, the important role of Micro RNA in the process of heart failure has received wide attention. A variety of specific Micro RNA may become an important marker for the diagnosis of heart failure in the future, providing better clinical ideas for the diagnosis and treatment of heart failure.This article reviews the involvement of Micro RNA in the pathogenesis of heart failure, its relationship with heart failure biomarkers and its application prospects in the treatment of heart failure, in order to provide references for clinical treatment of the disease.

参考文献/References:

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更新日期/Last Update: 1900-01-01