[1]吕雅琴,许宝洁,李志城.高频重复经颅磁刺激对酒精依赖患者焦虑抑郁情绪及复饮率的影响[J].医学信息,2021,34(04):133-135.[doi:10.3969/j.issn.1006-1959.2021.04.035]
　LV Ya-qin,XU Bao-jie,LI Zhi-cheng.Effect of High-frequency Repetitive Transcranial Magnetic Stimulation on Anxiety,Depression and Re-drinking Rate in Alcohol Dependent Patients[J].Medical Information,2021,34(04):133-135.[doi:10.3969/j.issn.1006-1959.2021.04.035]
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高频重复经颅磁刺激对酒精依赖患者焦虑抑郁情绪及复饮率的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年04期
页码:
133-135
栏目:
临床研究
出版日期:
2021-02-15

文章信息/Info

Title:
Effect of High-frequency Repetitive Transcranial Magnetic Stimulation on Anxiety,Depression and Re-drinking Rate in Alcohol Dependent Patients
文章编号:
1006-1959（2021）04-0133-03
作者:
吕雅琴; 许宝洁; 李志城
（广州市番禺区第三人民医院精神科，广东 广州 511483）
Author(s):
LV Ya-qin; XU Bao-jie; LI Zhi-cheng
(Department of Psychiatry,the Third People’s Hospital of Panyu District,Guangzhou 511483,Guangdong,China)
关键词:
高频重复经颅磁刺激; 酒精依赖; 焦虑; 抑郁; 复饮
Keywords:
High frequency repetitive transcranial magnetic stimulation; Alcohol dependence; Anxiety; Depression; Re-drinking
分类号:
R473.74
DOI:
10.3969/j.issn.1006-1959.2021.04.035
文献标志码:
A
摘要:
目的 探讨高频重复经颅磁刺激（rTMS）对酒精依赖患者焦虑抑郁情绪和复饮率的影响。方法 选取2018年10月~2020年1月在广州市番禺区第三人民医院住院的120例酒依赖患者，采用随机数字表法分为研究组（60例）和对照组（60例）。两组均接受地西泮替代治疗，研究组给予rTMS，对照组给予伪刺激，对两组患者进行密西根酒精调查表（MAST）、抑郁自评量表（SDS）、焦虑自评量表（SAS）、副反应评定量表（TESS）评定，并于出院6个月后进行复饮情况调查。结果 治疗后第2、4、6周末，两组MAST评分均较治疗前降低，且研究组低于对照组，差异有统计学意义（P＜0.05）；治疗后第2、4、6周末，两组SAS评分均较治疗前降低，且研究组低于对照组，差异有统计学意义（P＜0.05）；治疗后第2、4、6周末，两组SDS评分均较治疗前降低，且研究组低于对照组，差异有统计学意义（P＜0.05）；治疗后第2、4、6周末，两组TESS评分比较差异无统计学意义（P＞0.05）；研究组复饮率为11.67%，低于对照组的26.67%，差异有统计学意义（P＜0.05）；两组不良反应发生率及实验室检查结果比较，差异无统计学意义（P＞0.05）。结论 高频rTMS有助于改善酒依赖患者急性戒断后的焦虑抑郁情绪，并降低复饮率。
Abstract:
Objective To explore the effect of high-frequency repetitive transcranial magnetic stimulation (rTMS) on the anxiety and depression mood and re-drinking rate of alcohol dependent patients.Methods A total of 120 alcohol dependent patients who were hospitalized in the Third People’s Hospital of Panyu District, Guangzhou City from October 2018 to January 2020 were selected and divided into a study group (60 cases) and a control group (60 cases) by random number table.Both groups received diazepam replacement therapy, the study group was given rTMS, and the control group was given pseudo-stimulation. The two groups were given the Michigan Alcohol Questionnaire (MAST), Depression Self-Rating Scale (SDS), and Self-Rating Anxiety Scale ( SAS), Adverse Reaction Rating Scale (TESS), and a survey of re-drinking 6 months after discharge.Results The MAST scores of the two groups were lower than before the treatment on the second, fourth, and sixth weekends after treatment, and the study group was lower than the control group, the difference was statistically significant (P＜0.05);At 2, 4, and 6 weekends after treatment, the SAS scores of the two groups were lower than before treatment, and the study group was lower than the control group, the difference was statistically significant (P＜0.05);At 2, 4, and 6 weekends after treatment, the SDS scores of the two groups were lower than before treatment, and the study group was lower than the control group, the difference was statistically significant (P＜0.05);There was no significant difference in TESS scores between the two groups on the second, fourth, and sixth weekends after treatment (P＞0.05);The re-drinking rate in the study group was 11.67%, which was lower than the 26.67% in the control group, the difference was statistically significant (P＜0.05);There was no significant difference in the incidence of adverse reactions and laboratory test results between the two groups (P＞0.05).Conclusion High-frequency rTMS can help improve the anxiety and depression of patients with alcohol dependence after acute withdrawal, and reduce the rate of re-drinking.

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更新日期/Last Update: 1900-01-01