[1]高 文,李 科,李雪萍,等.肌球蛋白轻链激酶介导的肌球蛋白调节轻链磷酸化研究[J].医学信息,2021,34(08):28-30,35.[doi:10.3969/j.issn.1006-1959.2021.08.008]
 GAO Wen,LI Ke,LI Xue-ping,et al.Study on Myosin Light Chain Phosphorylation Mediated by Myosin Light Chain Kinase[J].Medical Information,2021,34(08):28-30,35.[doi:10.3969/j.issn.1006-1959.2021.08.008]
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肌球蛋白轻链激酶介导的肌球蛋白调节轻链磷酸化研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年08期
页码:
28-30,35
栏目:
综述
出版日期:
2021-04-15

文章信息/Info

Title:
Study on Myosin Light Chain Phosphorylation Mediated by Myosin Light Chain Kinase
文章编号:
1006-1959(2021)08-0028-04
作者:
高 文李 科李雪萍
(1.西安医学院临床医学院,陕西 西安 710021; 2.西安医学院第一附属医院,陕西 西安 710003)
Author(s):
GAO WenLI KeLI Xue-pinget al.
(1.The Clinical Medicine College of Xi’an Medical University,Xi’an 710021,Shaanxi,China; 2.The First Affiliated Hospital of Xi’an Medical University,Xi’an 710003,Shaanxi,China)
关键词:
肌球蛋白轻链激酶肌球蛋白调节轻链肌肉收缩
Keywords:
Myosin light chain kinaseMyosin regulatory light chainMuscle contraction
分类号:
Q512.2
DOI:
10.3969/j.issn.1006-1959.2021.08.008
文献标志码:
A
摘要:
肌球蛋白轻链激酶(MLCK)是一种Ca2+/CaM(钙调素)依赖性蛋白激酶,通过介导肌球蛋白调节轻链(RLC)磷酸化促进肌肉的收缩。近年来研究发现RLC磷酸化在细胞病理生理功能中起着重要作用,本文就MLCK介导的RLC磷酸化最新研究进展作一综述。
Abstract:
Myosin light chain kinase (MLCK) is a Ca2+/CaM (calmodulin)-dependent protein kinase that promotes muscle contraction by mediating myosin-regulated light chain (RLC) phosphorylation.In recent years, studies have found that RLC phosphorylation plays an important role in cell pathophysiological functions. This article reviews the latest research progress of MLCK-mediated RLC phosphorylation.

参考文献/References:

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更新日期/Last Update: 1900-01-01