[1]陈智丹,张远起.中性粒细胞与淋巴细胞比值对恶性肿瘤预后的影响[J].医学信息,2021,34(08):57-59.[doi:10.3969/j.issn.1006-1959.2021.08.015]
 CHEN Zhi-dan,ZHANG Yuan-qi.The Influence of the Ratio of Neutrophils to Lymphocytes on the Prognosis of Malignant Tumors[J].Medical Information,2021,34(08):57-59.[doi:10.3969/j.issn.1006-1959.2021.08.015]
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中性粒细胞与淋巴细胞比值对恶性肿瘤预后的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年08期
页码:
57-59
栏目:
综述
出版日期:
2021-04-15

文章信息/Info

Title:
The Influence of the Ratio of Neutrophils to Lymphocytes on the Prognosis of Malignant Tumors
文章编号:
1006-1959(2021)08-0057-03
作者:
陈智丹张远起
(广东医科大学,广东 湛江 524000)
Author(s):
CHEN Zhi-danZHANG Yuan-qi
(Guangdong Medical University,Zhanjiang 524000,Guangdong,China)
关键词:
中性粒细胞与淋巴细胞比值恶性肿瘤乳腺癌泌尿系肿瘤胃肠道肿瘤
Keywords:
Neutrophil to lymphocyte ratioMalignant tumorBreast cancerUrinary system tumorGastrointestinal tumor
分类号:
R73
DOI:
10.3969/j.issn.1006-1959.2021.08.015
文献标志码:
A
摘要:
全身性炎症在促进肿瘤进展中起重要作用。中性粒细胞与淋巴细胞比值(NLR)作为易于确定且具有成本效益的炎症生物标志物,已被发现与肿瘤预后密切相关,可以预测多种恶性肿瘤患者的生存情况。多项研究表明,NLR与泌尿系恶性肿瘤、胃肠道恶性肿瘤、非小细胞肺癌、子宫癌、乳腺癌的预后有关。当NLR处于较高水平时,恶性肿瘤患者的总生存率(OS)、无进展生存率(PFS)和无复发生存率(RFS)则较少,意味着患者的预后较差。本文主要就NLR与泌尿系恶性肿瘤、胃肠道恶性肿瘤、非小细胞肺癌、子宫癌、乳腺癌等恶性肿瘤预后的相关研究作一综述,旨在为临床判断恶性肿瘤患者的预后转归提供帮助。
Abstract:
Systemic inflammation plays an important role in promoting tumor progression.Neutrophil to lymphocyte ratio (NLR), as an easy to determine and cost-effective inflammatory biomarker, has been found to be closely related to tumor prognosis and can predict the survival of patients with multiple malignancies.A number of studies have shown that NLR is related to the prognosis of urinary system cancer, gastrointestinal cancer, non-small cell lung cancer, uterine cancer, and breast cancer. When the NLR is at a high level, the overall survival rate (OS), progression-free survival rate (PFS) and recurrence-free survival rate (RFS) of patients with malignant tumors are less, which means that the patient’s prognosis is poor.This article mainly reviews the prognosis of NLR and urinary system malignant tumors, gastrointestinal malignant tumors, non-small cell lung cancer, uterine cancer, breast cancer and other malignant tumors.It aims to provide help for clinical judgment of the prognosis of patients with malignant tumors.

参考文献/References:

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更新日期/Last Update: 1900-01-01