[1]陈思源,郑袁如,彭 琼.Strate、NOBLADS和Oakland评分评价急性下消化道出血患者预后的价值[J].医学信息,2021,34(08):81-84.[doi:10.3969/j.issn.1006-1959.2021.08.021]
 CHEN Si-yuan,ZHENG Yuan-ru,PENG Qiong.The Value of Strate,NOBLADS and Oakland Scores in Evaluating the Prognosis of Patients with Acute Lower Gastrointestinal Bleeding[J].Medical Information,2021,34(08):81-84.[doi:10.3969/j.issn.1006-1959.2021.08.021]
点击复制

Strate、NOBLADS和Oakland评分评价急性下消化道出血患者预后的价值()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年08期
页码:
81-84
栏目:
论著
出版日期:
2021-04-15

文章信息/Info

Title:
The Value of Strate,NOBLADS and Oakland Scores in Evaluating the Prognosis of Patients with Acute Lower Gastrointestinal Bleeding
文章编号:
1006-1959(2021)08-0081-04
作者:
陈思源郑袁如彭 琼
(安徽医科大学第三附属医院/合肥市第一人民医院消化内科,安徽 合肥 230001)
Author(s):
CHEN Si-yuanZHENG Yuan-ruPENG Qiong
(The Third Affiliated Hospital of Anhui Medical University/Department of Gastroenterology,Hefei First People’s Hospital, Hefei 230001,Anhui,China)
关键词:
急性下消化道出血Strate评分NOBLADS评分Oakland评分
Keywords:
Acute lower gastrointestinal bleedingStrate scoreNOBLADS scoreOakland score
分类号:
R573
DOI:
10.3969/j.issn.1006-1959.2021.08.021
文献标志码:
A
摘要:
目的 研究Strate、NOBLADS和Oakland评分系统在急性下消化道出血患者预后评估中的应用价值。方法 选取2016年1月~2020年5月我院收治的213例急性下消化道出血患者,记录患者的临床资料,统计其Strate、NOBLADS和Oakland评分,根据是否为严重的下消化道出血、是否再出血、接受输血、死亡和是否接受内镜、介入或外科干预进行分组,比较不同分组患者Strate、NOBLADS和Oakland评分,采用受试者工作曲线(ROC)分析Strate、NOBLADS和Oakland评分预测患者发生严重的下消化道出血、再出血、输血、死亡和接受内镜、介入或外科干预的价值。结果 严重的下消化道出血、死亡、输血、再出血患者的Strate、NOBLADS评分均高于非严重的下消化道出血、非死亡、非输血、非再出血的患者,差异有统计学意义(P<0.05),但在是否接受干预方面,差异无统计学意义(P>0.05);严重的下消化道出血、输血、再出血、接受干预患者的Oakland评分均高于非严重的下消化道出血、非输血、非再出血及未接收干预患者,差异有统计学意义(P<0.05),在是否死亡方面,差异无统计学意义(P>0.05);ROC曲线显示,Strate、NOBLADS和Oakland评分预测是否为严重出血的AUC分别为0.852、0.787、0.883;预测再出血的AUC分别为0.701、0.702、0.724;预测输血的AUC分别为0.802、0.822、0.903;预测死亡的AUC分别为0.822、0.854、0.762。结论 Strate、NOBLADS和Oakland评分可作为急性下消化道出血患者严重程度和预后评估指标,Oakland评分预测严重程度和输血需求价值较高,NOBLADS评分预测患者死亡结局的价值较高。
Abstract:
Objective To study the application value of the Strate, NOBLADS and Oakland scoring systems in the prognosis assessment of patients with acute lower gastrointestinal bleeding.Methods 213 patients with acute lower gastrointestinal bleeding admitted to our hospital from January 2016 to May 2020 were selected.Record the patient’s clinical data and count their Strate, NOBLADS and Oakland scores,According to whether it is severe lower gastrointestinal bleeding, rebleeding, receiving blood transfusion, death, and whether receiving endoscopy, interventional or surgical intervention, they are divided into groups.Compare the Strate, NOBLADS and Oakland scores of patients in different groups,the receiver operating curve (ROC) was used to analyze the value of Strate, NOBLADS and Oakland scores in predicting whether patients have severe lower gastrointestinal bleeding, rebleeding, blood transfusion, death, and receiving endoscopic, interventional or surgical intervention.Results The Strate and NOBLADS scores of patients with severe lower gastrointestinal bleeding, death, blood transfusion, and rebleeding were higher than those of non-severe lower gastrointestinal bleeding, non-death, non-transfusion, and non-rebleeding patients,the difference was statistically significant (P <0.05),However, there was no statistically significant difference in whether to accept intervention or not (P>0.05);The Oakland scores of patients with severe lower gastrointestinal bleeding, blood transfusion, rebleeding, and intervention were all higher than those of non-severe lower gastrointestinal bleeding, non-transfusion, non-rebleeding, and patients who did not receive intervention,the difference was statistically significant (P<0.05).In terms of death, the difference was not statistically significant (P>0.05);The ROC curve showed that the AUC of Strate, NOBLADS and Oakland scores predicting whether severe bleeding was 0.852, 0.787, 0.883, respectively;The AUCs of rebleeding were 0.701, 0.702, 0.724; the AUCs of blood transfusion were 0.802, 0.822, 0.903;The AUC of death was 0.822, 0.854, and 0.766, respectively.Conclusion Strate, NOBLADS and Oakland scores can be used as evaluation indicators for the severity and prognosis of patients with acute lower gastrointestinal bleeding. Oakland scores are more valuable in predicting severity and blood transfusion requirements, and NOBLADS scores are more valuable in predicting the outcome of patients’ death.

参考文献/References:

[1]Moss AJ,Tuffaha H,Malik A.Lower GI bleeding:a review of current management,controversies and advances[J].International Journal of Colorectal Disease,2016,31(2):175-188. [2]Strate LL,Gralnek IM.ACG Clinical Guideline:Management of Patients With Acute Lower Gastrointestinal Bleeding[J].American Journal of Gastroenterology,2016,111(4):459-474. [3]Committee P,Davila RE,Rajan E,et al.ASGE Guideline: the role of endoscopy in the patient with lower-GI bleeding[J].Gastrointestinal Endoscopy,2005,62(5):656-660. [4]吴东等.急性下消化道出血的诊治[J].中华全科医师杂志,2017,16(5):337-341. [5]马娟,邓卫平,曾志刚.938例下消化道出血的临床病因分析[J].中华急诊医学杂志,2014,23(12):1358-136. [6]Camus M,Jensen DM,Ohning GV,et al.Comparison of Three Risk Scores to Predict Outcomes of Severe Lower Gastrointestinal Bleeding[J].Journal of Clinical Gastroenterology,2016,50(1):52-58. [7]Aoki T,Nagata N,Shimbo T,et al.Development and Validation of a Risk Scoring System for Severe Acute Lower Gastrointestinal Bleeding[J].Clin Gastroenterol Hepatol,2016,14(11):1562-1570. [8]Tomonori A,Atsuo Y,Naoyoshi N,et al.External validation of the NOBLADS score,a risk scoring system for severe acute lower gastrointestinal bleeding[J].PLoS One,2018,13(4):e0196514. [9]Strate LL,Saltzman JR,Ookubo R,et al.Validation of a clinical prediction rule for severe acute lower intestinal bleeding[J].American Journal of Gastroenterology,2005,100(8):1821. [10]Oakland K,Jairath V,Uberoi R,et al.Derivation and validation of a novel risk score for safe discharge after acute lower gastrointestinal bleeding:a modelling study[J].Lancet Gastroenterol Hepatol,2017,2(9):635-643. [11]Barkun AN,Almadi M,Kuipers EJ,et al.Management of Nonvariceal Upper Gastrointestinal Bleeding:Guideline Recommendations From the International Consensus Group[J].Annals of Internal Medicine,2019,171(11):805-822. [12]Tapaskar N,Jones B,Mei S,et al.540 Comparison of Clinical Prediction Tools and Identification of Risk Factors for Adverse Outcomes in Acute Lower Gastrointestinal Bleeding[J].Gastrointestinal Endoscopy,2019,89(5):1005-1013. [13]Brusselaers N,Lagergren J.The Charlson Comorbidity Index in Registry-based Research[J].Methods of Information in Medicine,2017,56(5):401-406. [14]Bond A,Smith PJ.British Society of Gastroenterology: Diagnosis and management of acute lower gastrointestinal bleeding[J].Frontline Gastroenterology,2019,10(4):417-420. [15]Ghassemi KA,Jensen DM.Lower GI Bleeding:Epidemiology and Management[J].Current Gastroenterology Reports,2013,15(7):333. [16]Xavier SA,Machado FJ,Magalhaes JT,et al.Acute lower gastrointestinal bleeding:are STRATE and BLEED scores valid in clinical practice[J].Colorectal Disease,2019,21(3):357-364. [17]Oakland K,Chadwick G,East JE,et al.Diagnosis and management of acute lower gastrointestinal bleeding:Guidelines from the British Society of Gastroenterology[J].Gut,2019,68(5):776-789.

更新日期/Last Update: 1900-01-01