[1]鲍爱春,刘芳英,朱静静,等.慢性鼻-鼻窦炎与支气管哮喘变应原特征分析[J].医学信息,2021,34(09):81-83.[doi:10.3969/j.issn.1006-1959.2021.09.021]
　BAO Ai-chun,LIU Fang-ying,ZHU Jing-jing,et al.Analysis of Allergen Characteristics of Chronic Rhinosinusitis and Bronchial Asthma[J].Medical Information,2021,34(09):81-83.[doi:10.3969/j.issn.1006-1959.2021.09.021]
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慢性鼻-鼻窦炎与支气管哮喘变应原特征分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年09期
页码:
81-83
栏目:
论著
出版日期:
2021-05-01

文章信息/Info

Title:
Analysis of Allergen Characteristics of Chronic Rhinosinusitis and Bronchial Asthma
文章编号:
1006-1959（2021）09-0081-03
作者:
鲍爱春; 刘芳英; 朱静静; 等
（上海中医药大学附属曙光医院宝山分院耳鼻咽喉科1，呼吸内科2，上海 201900）
Author(s):
BAO Ai-chun; LIU Fang-ying; ZHU Jing-jing; et al.
(Department of Otorhinolaryngology1,Department of Respiratory Medicine2,Baoshan Branch of Shuguang Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 201900,China)
关键词:
慢性鼻-鼻窦炎; 支气管哮喘; 变应原; 食物致敏
Keywords:
Chronic rhinosinusitis; Bronchial asthma; Allergen; Food sensitization
分类号:
R765.4
DOI:
10.3969/j.issn.1006-1959.2021.09.021
文献标志码:
A
摘要:
目的 分析慢性鼻-鼻窦炎（CRS）与支气管哮喘（BA）患者的变应原特征及临床意义。方法 选取2017年2月~2018年4月到我院耳鼻喉科手术治疗的慢性鼻-鼻窦炎127例患者作为研究对象，按照患者是否伴发鼻息肉分为CRS不伴鼻息肉组（CRSsNP组）45例与CRS伴鼻息肉组（CRSwNP组）82例，同时选择该时期到我院呼吸内科住院治疗的支气管哮喘（BA组）患者43例作为对照组，分析三组患者变应原特征。结果 CRS患者变应原总阳性率为74.02%。CRSwNP组、CRSsNP组、BA组三组变应原总阳性率分别为：76.83%、68.89%、72.09%。三组均以吸入性及混合型变应原过敏为主，食物变应原比例增高。CRS组吸入性变应原以花粉为主。CRSwNP、CRSsNP、BA患者的变应原分布情况具有高度的一致性，吸入性和食物变应原分布比例、各类变应原分布比例、单一和多种变应原分布比较，差异无统计学意义（P＞0.05）。结论 CRSwNP、CRSsNP、BA患者变应原特征呈现高度一致性。变应性因素在CRS、BA患者中可能存在相似的发病机制。食物变应原在CRS的发生发展中的作用机制尚需深入研究。
Abstract:
Objective To analyze the characteristics and clinical significance of allergens in patients with chronic rhinosinusitis (CRS) and bronchial asthma (BA).Methods A total of 127 patients with chronic rhinosinusitis who had undergone surgery in the Department of Otolaryngology in our hospital from February 2017 to April 2018 were selected as the research objects.According to whether the patients were accompanied by nasal polyps, they were divided into 45 cases with CRS without nasal polyps (CRSsNP group) and 82 cases with CRS with nasal polyps (CRSwNP group).At the same time, 43 patients with bronchial asthma (BA group) who were hospitalized in the Department of Respiratory Medicine of our hospital during this period were selected as the control group, and the allergenic characteristics of the three groups of patients were analyzed.Results The total positive rate of allergens in CRS patients was 74.02%. The total positive rates of allergens in the CRSwNP group, CRSsNP group, and BA group were 76.83%, 68.89%, and 72.09%, respectively.All three groups were mainly allergic to inhaled and mixed allergens, and the proportion of food allergens increased. In the CRS group, inhalation allergens were mainly pollen.The distribution of allergens in CRSwNP, CRSsNP, and BA patients was highly consistent.There were no statistically significant differences in the distribution ratios of inhalation and food allergens, the distribution ratios of various allergens, and the distribution of single and multiple allergens (P＞0.05).Conclusion The allergen characteristics of CRSwNP, CRSsNP and BA patients are highly consistent. Allergic factors may have similar pathogenesis in CRS and BA patients. The mechanism of food allergens in the occurrence and development of CRS still needs in-depth study.

参考文献/References:

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更新日期/Last Update: 1900-01-01