[1]张 鹏.肾结石患者尿钙、镁、钠、钾与尿阳离子的相关性分析[J].医学信息,2021,34(18):110-112.[doi:10.3969/j.issn.1006-1959.2021.18.028]
　ZHANG Peng.Correlation Analysis of Urinary Calcium,Magnesium,Sodium,Potassium andUrinary Cations in Patients with Kidney Stones[J].Medical Information,2021,34(18):110-112.[doi:10.3969/j.issn.1006-1959.2021.18.028]
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肾结石患者尿钙、镁、钠、钾与尿阳离子的相关性分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年18期
页码:
110-112
栏目:
论著
出版日期:
2021-09-18

文章信息/Info

Title:
Correlation Analysis of Urinary Calcium,Magnesium,Sodium,Potassium andUrinary Cations in Patients with Kidney Stones
文章编号:
1006-1959（2021）18-0110-03
作者:
张 鹏
佳木斯市中心医院泌尿外科，黑龙江 佳木斯 154001
Author(s):
ZHANG Peng
Department of Urology,The Central Hospitital of Jia Mu Si City,Jiamusi 154001,Heilongjiang,China
关键词:
肾结石; 尿阳离子; 钙; 镁; 钠; 钾
Keywords:
Kidney stones; Urinary cations; Calcium; Magnesium; Sodium; Potassium
分类号:
R692.4
DOI:
10.3969/j.issn.1006-1959.2021.18.028
文献标志码:
A
摘要:
目的 探讨肾结石患者尿液中含有的钙、镁、钠、钾等相关阳离子与肾结石发病的相关性。方法 选取我院2016年10月-2020年10月收治的110例肾结石患者设为研究组，另取同期100例健康者作为对照组。比较两组24h尿液中钙、镁、钠、钾离子的平均排泄量及每克肌酐平均浓度，并应用线性回归方程分析钙对镁、钙对钠、钙对钾的相关系数，分析两组24h尿液收集和清晨尿液样本的肌酐浓度。结果 研究组患者24h尿液中钙离子的排泄量高于对照组，镁、钠和钾的排泄量低于对照组，差异有统计学意义（P＜0.05）；研究组患者24h尿液中钙、镁的每克肌酐平均浓度高于对照组，钠、钾的每克肌酐平均浓度低于对照组，差异有统计学意义（P＜0.05）；两组阳离子对间都有显著的相关性（P＜0.05）；采用协方差分析比较两组每对阳离子的线性回归线，结果显示钙对镁的回归线在坡度和位置上均无统计学差异（P＞0.05）；钙对钠的3条回归线，无论是倾斜还是体位均无统计学差异（P＞0.05）；两组钙、钾相对排泄量在坡度和位置上无统计学差异（P＞0.05）；研究组24h尿液收集和清晨尿液样本的肌酐浓度发现数值低于对照组，差异有统计学意义（P＜0.05）。结论 肾结石患者清晨尿液中钙阳离子浓度增加，而且肾结石患者在夜间尿液中高浓度的钙离子和低浓度的镁离子可能是导致肾结石的原因之一。
Abstract:
Objective To investigate the relationship between calcium, magnesium, sodium, potassium and other related cations in urine of patients with kidney stones and the pathogenesis of kidney stones.Methods A total of 110 patients with kidney stones admitted to our hospital from October 2016 to October 2020 were selected as the study group, and 100 healthy patients during the same period were selected as the control group.The average excretion of calcium, magnesium, sodium, and potassium ions in the urine and the average concentration of creatinine per gram in the two groups within 24 h were measured, and the linear regression equation was used to analyze the correlation coefficients of calcium to magnesium, calcium to sodium, and calcium to potassium. The creatinine concentration of 24 h urine collection and morning urine samples in the group.Results The excretion of calcium ions in urine in the study group was higher than that of the control group within 24 h, and the excretion of magnesium, sodium and potassium was lower than that of the control group, the difference was statistically significant (P＜0.05);The average concentration of calcium and magnesium per gram of creatinine in the 24 h urine of the study group was higher than that of the control group, and the average concentration of sodium and potassium per gram of creatinine was lower than that of the control group, the difference was statistically significant(P＜0.05);There was a significant correlation between cation pairs in all groups (P＜0.05);Covariance analysis was used to compare the linear regression lines of each pair of cations in the study group and the control group. The results showed that the regression line of calcium versus magnesium had no difference in slope and position (P＞0.05).The three regression lines of calcium versus sodium, no matter whether it was tilt or body position, had no statistical difference (P＞0.05);The relative excretion of calcium and potassium in the study group and the control group had no statistical difference in slope and position (P＞0.05);The creatinine concentration of the 24 h urine collection and morning urine samples in the study group was found to be lower than that of the control group, the difference was statistically significant (P＜0.05).Conclusion The concentration of calcium cations in the urine of patients with kidney stones increases in the morning, and the high concentration of calcium ions and low concentrations of magnesium ions in the urine of patients with kidney stones at night may be one of the causes of kidney stones.

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更新日期/Last Update: 1900-01-01