[1]杨晓飞,格根塔娜,杨昱藩.肿瘤坏死因子-α在慢性根尖周炎中的作用研究[J].医学信息,2021,34(21):46-48.[doi:10.3969/j.issn.1006-1959.2021.21.011]
 YANG Xiao-fei,GEGEN Ta-na,YANG Yu-fan.Role of Tumor Necrosis Factor-α in Chronic Apical Periodontitis[J].Medical Information,2021,34(21):46-48.[doi:10.3969/j.issn.1006-1959.2021.21.011]
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肿瘤坏死因子-α在慢性根尖周炎中的作用研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年21期
页码:
46-48
栏目:
综述
出版日期:
2021-11-01

文章信息/Info

Title:
Role of Tumor Necrosis Factor-α in Chronic Apical Periodontitis
文章编号:
1006-1959(2021)21-0046-03
作者:
杨晓飞格根塔娜杨昱藩
(1.内蒙古医科大学口腔医学院,内蒙古 呼和浩特 010000;2.内蒙古医科大学附属医院口腔科,内蒙古 呼和浩特 010000;3.内蒙古自治区人民医院口腔科,内蒙古 呼和浩特 010000)
Author(s):
YANG Xiao-feiGEGEN Ta-naYANG Yu-fan
(1.School of Stomatology,Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia,China;2.Department of Stomatology,the Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010000,Inner Mongolia,China;3.Department of Stomatology,Inner M
关键词:
慢性根尖周炎肿瘤坏死因子-α生物学效应
Keywords:
Chronic apical periodontitisTumor necrosis factor-αBiological effect
分类号:
R781.34+1
DOI:
10.3969/j.issn.1006-1959.2021.21.011
文献标志码:
A
摘要:
炎症细胞因子肿瘤坏死因子-α(TNF-α)作为促炎细胞因子,其在许多炎症性疾病中起着重要的作用。而慢性根尖周炎是一种以根尖周组织炎症和牙槽骨破坏为特征的慢性炎症性疾病,大量研究表明TNF-α可能与慢性根尖周炎的发病机制有关。本文就TNF-α的生产细胞及其家族成员与受体、信号通路、生物学效应及其在慢性根尖周炎中的表达及作用作一综述,以期为慢性根尖周炎诊治提供参考。
Abstract:
Tumor necrosis factor-α (TNF-α), a proinflammatory cytokine, plays an important role in many inflammatory diseases. Chronic apical periodontitis is a chronic inflammatory disease characterized by periapical tissue inflammation and alveolar bone destruction. A large number of studies have shown that TNF-α may be related to the pathogenesis of chronic periapical periodontitis. This article reviews the production cells of TNF-α and its family members and receptors, signaling pathways, biological effects and their expression and role in chronic periapical periodontitis, in order to provide reference for the diagnosis and treatment of chronic periapical periodontitis.

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更新日期/Last Update: 1900-01-01