[1]李清霞.超声淋巴结穿刺联合血清TSH、PAI-1水平对甲状腺癌患者颈部淋巴结转移的诊断效果[J].医学信息,2021,34(23):175-177.[doi:10.3969/j.issn.1006-1959.2021.23.053]
　LI Qing-xia.Diagnostic Effect of Ultrasound Lymph Node Puncture Combined with Serum TSH and PAI-1 Levels on Cervical Lymph Node Metastasis in Patients with Thyroid Cancer[J].Medical Information,2021,34(23):175-177.[doi:10.3969/j.issn.1006-1959.2021.23.053]
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超声淋巴结穿刺联合血清TSH、PAI-1水平对甲状腺癌患者颈部淋巴结转移的诊断效果()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年23期
页码:
175-177
栏目:
诊疗技术
出版日期:
2021-12-01

文章信息/Info

Title:
Diagnostic Effect of Ultrasound Lymph Node Puncture Combined with Serum TSH and PAI-1 Levels on Cervical Lymph Node Metastasis in Patients with Thyroid Cancer
文章编号:
1006-1959（2021）23-0175-03
作者:
李清霞
（余干县人民医院B超室，江西 余干 335100）
Author(s):
LI Qing-xia
(B-ultrasound Room,Yugan County People’s Hospital,Yugan 335100,Jiangxi,China)
关键词:
超声淋巴结穿刺; TSH; PAI-1; 甲状腺癌; 颈部淋巴结转移
Keywords:
Ultrasound lymph node puncture; TSH; PAI-1; Thyroid cancer; Cervical lymph node metastasis
分类号:
R736.1
DOI:
10.3969/j.issn.1006-1959.2021.23.053
文献标志码:
A
摘要:
目的 探讨超声淋巴结穿刺联合血清TSH、PAI-1水平对甲状腺癌患者颈部淋巴结转移的诊断效果。方法 选取我院2017年6月-2019年12月收治的200例甲状腺癌患者作为研究对象，根据淋巴结转移情况分为转移转移组（n=65）和未转移组（n=135）。分析转移组超声图像特征、超声引导下甲状腺结节细针抽吸活检术（US-FNA）评估甲状腺癌淋巴结转移的价值，比较两组血清TSH、PAI-1水平。采用受试者工作曲线（ROC曲线）分析TSH、PAI-1及联合超声淋巴结穿刺诊断对甲状腺癌淋巴结转移的诊断效果。结果 超声结果显示淋巴结内淋巴门消失，部分周界模糊，内部呈现短条状血流信号，回声增强。US-FNA对甲状腺癌淋巴结转移诊断总准确率为89.00%；转移组血清TSH、PAI-1水平高于未转移组（P＜0.05）；血清TSH、PAI-1诊断甲状腺癌淋巴转移的AUC分别为0.781和0.777；超声淋巴结穿刺联合血清TSH、PAI-1水平诊断甲状腺癌患者颈部淋巴结转移的AUC分别为0.849和0.759，三者联合诊断的AUC为0.896，优于单个或两两联合诊断。结论 超声淋巴结穿刺联合血清TSH、PAI-1水平诊断甲状腺癌颈部淋巴结转移灵敏度、准确度较高，结果可靠。
Abstract:
Objective To investigate the diagnostic effect of ultrasound lymph node puncture combined with serum TSH and PAI-1 levels on cervical lymph node metastasis in patients with thyroid cancer.Methods A total of 200 patients with thyroid cancer admitted to our hospital from June 2017 to December 2019 were selected as the study subjects. According to lymph node metastasis, they were divided into lymph node metastasis group (n=65) and non-metastasis group (n=135). The characteristics of ultrasound images in lymph node metastasis group and the value of ultrasound-guided fine needle aspiration biopsy (US-FNA) in evaluating lymph node metastasis of thyroid cancer were analyzed. The levels of serum TSH and PAI-1 were compared between the two groups. The receiver operating curve (ROC curve) was used to analyze the diagnostic effect of TSH, PAI-1 and combined ultrasound lymph node biopsy on lymph node metastasis of thyroid cancer.Results The ultrasound results showed that the lymphatic hilus disappeared, part of the perimeter was blurred, and the internal blood flow signal was short strip, and the echo was enhanced. The total diagnostic accuracy of US-FNA for lymph node metastasis of thyroid cancer was 89.00%. Serum TSH and PAI-1 levels in patients with lymph node metastasis of thyroid cancer were higher than those in the non-metastasis group (P<0.05). The AUC of serum TSH and PAI-1 in diagnosing lymph node metastasis of thyroid carcinoma were 0.781 and 0.777, respectively. The AUC of ultrasound lymph node puncture combined with serum TSH and PAI-1 levels in the diagnosis of cervical lymph node metastasis in patients with thyroid cancer were 0.849 and 0.759, respectively. The AUC of combined diagnosis of the three was 0.896, which was better than single or double combined diagnosis.Conclusion Ultrasound lymph node puncture combined with serum TSH and PAI-1 levels in the diagnosis of cervical lymph node metastasis of thyroid cancer has high sensitivity and accuracy, and the results are reliable.

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更新日期/Last Update: 1900-01-01