[1]肖 健.静脉溶栓桥接动脉内取栓治疗颅内血管闭塞的临床效果及安全性观察[J].医学信息,2021,(24):117-119.[doi:10.3969/j.issn.1006-1959.2021.24.029]
 XIAO Jian.Clinical Effect and Safety of Intravenous Thrombolysis Bridging Artery Embolization in the Treatment of Intracranial Vascular Occlusion[J].Medical Information,2021,(24):117-119.[doi:10.3969/j.issn.1006-1959.2021.24.029]
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静脉溶栓桥接动脉内取栓治疗颅内血管闭塞的临床效果及安全性观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
期数:
2021年24期
页码:
117-119
栏目:
临床研究
出版日期:
2021-12-15

文章信息/Info

Title:
Clinical Effect and Safety of Intravenous Thrombolysis Bridging Artery Embolization in the Treatment of Intracranial Vascular Occlusion
文章编号:
1006-1959(2021)24-0117-03
作者:
肖 健
(宁都县人民医院神经内科,江西 宁都 342800)
Author(s):
XIAO Jian
(Department of Neurology,Ningdu County People’s Hospital,Ningdu 342800,Jiangxi,China)
关键词:
静脉溶栓桥接动脉内取栓术颅内血管闭塞
Keywords:
Intravenous thrombolysisBridge artery thrombectomyIntracranial vascular occlusion
分类号:
R743
DOI:
10.3969/j.issn.1006-1959.2021.24.029
文献标志码:
A
摘要:
目的 观察静脉溶栓桥接动脉内取栓治疗颅内血管闭塞的临床效果及安全性。方法 选取2018年1月-2021年5月在我院治疗的72例颅内血管闭塞患者为研究对象,采用随机数字表法分为对照组和观察组,各36例。对照组采用阿替普酶静脉溶栓治疗,观察组在对照组基础上给予桥接动脉内取栓术联合抽吸治疗。比较两组临床静脉和动脉再通时间、血管再通率、神经功能缺损(NIHSS)评分、取栓次数、改良Rankin预后评分以及并发症发生情况。结果 观察组静脉和动脉再通时间均短于对照组,差异有统计学意义(P<0.05)。观察组血管再通率为94.44%,高于对照组的83.33%,差异有统计学意义(P<0.05)。术后,两组NIHSS评分均低于术前,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组平均取栓次数、改良Rankin预后评分均低于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为8.33%,低于对照组的19.44%,差异有统计学意义(P<0.05)。结论 静脉溶栓桥接动脉内支架联合抽吸取栓术治疗颅内血管闭塞的临床效果理想,可提高血管再通率,缩短血管再通时间,降低神经功能缺损评分,减少取栓次数,改善预后,且并发症发生率少,是一种有效、安全的治疗方法。
Abstract:
Objective To observe the clinical effect and safety of intravenous thrombolysis bridging artery embolization in the treatment of intracranial vascular occlusion.Methods A total of 72 patients with intracranial vascular occlusion treated in our hospital from January 2018 to May 2021 were selected as subjects. They were divided into control group and observation group by random number table method, with 36 cases in each group. The control group was treated with intravenous thrombolysis with alteplase, and the observation group was treated with bridging artery thrombectomy combined with aspiration on the basis of the control group. The clinical venous and arterial recanalization time, recanalization rate, NIHSS score, number of thrombectomy, modified Rankin prognostic score and complications were compared between the two groups.Results The vein and artery recanalization time in the observation group were shorter than those in the control group, the differences were statistically significant (P<0.05). The recanalization rate in the observation group was 94.44%, which was higher than 83.33% in the control group, and the difference was statistically significant (P<0.05). After operation, the NIHSS scores of the two groups were lower than those before operation, and those of the observation group were lower than the control group, the differences were statistically significant (P<0.05). The average number of embolectomy and improved Rankin prognosis score in the observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The incidence of complications in the observation group was 8.33%, which was lower than 19.44% in the control group, and the difference was statistically significant (P<0.05).Conclusion The clinical effect of intravenous thrombolysis bridging artery stent combined with thrombus aspiration in the treatment of intracranial vascular occlusion is ideal, which can improve the recanalization rate, shorten the recanalization time, reduce the neurological deficit score, reduce the number of thrombus extraction, and improve the prognosis. It is an effective and safe treatment method with fewer complications.

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更新日期/Last Update: 1900-01-01