[1]高志芳.NSAIDs相关的小肠损伤机制及防治研究[J].医学信息,2022,35(04):60-64.[doi:10.3969/j.issn.1006-1959.2022.04.016]
 GAO Zhi-fang.The Mechanism and Prevention of NSAIDs-related Small Intestinal Injury[J].Medical Information,2022,35(04):60-64.[doi:10.3969/j.issn.1006-1959.2022.04.016]
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NSAIDs相关的小肠损伤机制及防治研究()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年04期
页码:
60-64
栏目:
综述
出版日期:
2022-02-15

文章信息/Info

Title:
The Mechanism and Prevention of NSAIDs-related Small Intestinal Injury
文章编号:
1006-1959(2022)04-0060-05
作者:
高志芳
重庆市渝北区人民医院消化内科,重庆 401120
Author(s):
GAO Zhi-fang
Department of Gastroenterology,Chongqing Yubei District People’s Hospital,Chongqing 401120,China
关键词:
非甾体抗炎药小肠损伤内窥镜
Keywords:
Non-steroidal anti-inflammatory drugsIntestinal injuryEndoscope
分类号:
R595.3
DOI:
10.3969/j.issn.1006-1959.2022.04.016
文献标志码:
A
摘要:
非甾体抗炎药(NSAIDs)具有强大的解热、镇痛、抗炎、抗血小板作用,是临床最常用的药物之一,但有一定的胃肠道毒副作用。长期以来,临床医生比较重视NSAIDs导致的胃黏膜损伤,而忽视了其对小肠黏膜的损伤。随着小肠镜、胶囊内镜等的发展,NSAIDs相关小肠损伤受到关注,但其机制尚未完全明确,且缺乏有效的治疗手段。本文主要就NSAIDs相关小肠损伤的机制及防治进展作一综述,以期为NSAIDs致小肠黏膜损伤的防治提供参考。
Abstract:
Nonsteroidal anti-inflammatory drugs (NSAIDs) have powerful antipyretic, analgesic, anti-inflammatory and antiplatelet effects, which are one of the most commonly used drugs in clinic, but have certain gastrointestinal side effects. For a long time, clinicians have paid more attention to the gastric mucosal damage caused by NSAIDs, but ignored its damage to the intestinal mucosa. With the development of enteroscopy and capsule endoscopy, NSAIDs-related small bowel injury has attracted more and more attention. However, the mechanism is still unclear and there is no effective treatment. This article reviews the mechanism and prevention of NSAIDs-related intestinal injury, in order to provide reference for the prevention and treatment of NSAIDs-induced intestinal mucosal injury.

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更新日期/Last Update: 1900-01-01