[1]艾 聪,马 扬.2018-2020年天津市河西区疑似预防接种异常反应监测情况分析[J].医学信息,2022,35(11):12-15.[doi:10.3969/j.issn.1006-1959.2022.11.004]
　AI Cong,MA Yang.Analysis on Monitoring of Adverse Events Following Immunization in Hexi District of Tianjin from 2018 to 2020[J].Medical Information,2022,35(11):12-15.[doi:10.3969/j.issn.1006-1959.2022.11.004]
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2018-2020年天津市河西区疑似预防接种异常反应监测情况分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年11期
页码:
12-15
栏目:
公共卫生信息学
出版日期:
2022-06-01

文章信息/Info

Title:
Analysis on Monitoring of Adverse Events Following Immunization in Hexi District of Tianjin from 2018 to 2020
文章编号:
1006-1959（2022）11-0012-04
作者:
艾 聪; 马 扬
（天津市河西区疾病预防控制中心免疫规划科，天津 300211）
Author(s):
AI Cong; MA Yang
(Department of Immune Programming,Centers for Disease Control and Prevention of Hexi District,Tianjin 300211,China)
关键词:
疑似预防接种异常反应; 心因性反应; 异常反应
Keywords:
Adverse events following immunization; Psychogenic reaction; Abnormal reaction
分类号:
R186
DOI:
10.3969/j.issn.1006-1959.2022.11.004
文献标志码:
A
摘要:
目的 分析2018-2020年天津市河西区疑似预防接种异常反应（AEFI）的发生特征，以期为疫苗安全使用提供科学依据。方法 通过中国AEFI信息管理系统收集天津市河西区2018-2020年发生的AEFI个案数据，通过天津市免疫规划信息管理系统收集2018-2020年度各类疫苗的接种数据，分析AEFI分类情况，以及AEFI时间、年龄、疫苗、临床诊断分布情况。结果 2018-2020年天津市河西区报告AEFI个案360例，其中一般反应344例，异常反应10例，偶合症6例，报告发生率为61.43/10万剂次；第一、二、三季度AEFI报告发生率均高于第四季度（P＜0.05）；≤1岁AEFI报告病例最多，其中以8月龄患儿居多；AEFI病例主要集中在接种疫苗后0~1 d，占全部病例的79.72%；涉及31种疫苗，其中报告发生率居前3位的疫苗为麻风疫苗、麻疹疫苗、AC-Hib三联疫苗，而报告例数居前3位的疫苗为百白破（无细胞）疫苗、水痘疫苗、麻风疫苗；临床诊断以发热/红肿/硬结为主的一般反应占97.22%，以过敏性皮疹为主的异常反应占1.67%。结论 2018-2020年天津市河西区AEFI报告发生率较低，AEFI监测体统运转正常，疫苗安全性较好，但仍要加大AEFI培训力度，提高与家长的沟通能力和反应处理水平，以减少负面影响。
Abstract:
Objective To analyze the characteristics of adverse events following immunization (AEFI) in Hexi District of Tianjin from 2018 to 2020, so as to provide scientific basis for safe use of vaccines.Methods The data of AEFI cases in Hexi District of Tianjin from 2018 to 2020 were collected by China AEFI information management system, and the vaccination data of various vaccines from 2018 to 2020 were collected by Tianjin immunization planning information management system. The classification of AEFI, and the distribution of AEFI time, age, vaccine and clinical diagnosis were analyzed.Results A total of 360 AEFI cases were reported in Hexi District of Tianjin from 2018-2020, which included 344 cases of general reaction, 10 cases of abnormal reaction and 6 accidental case, and the incidence rate of AEFI reported was 61.43 per 100 000 doses. The reported incidence of AEFI in the first, second and third quarters was higher than that in the fourth quarter (P<0.05). Most AEFI cases were reported under 1 year old, and most of them were children aged 8 months. AEFI cases were mainly concentrated in 0-1 days after vaccination, accounting for 79.72% of all cases; among the 31 vaccines involved, the top three reported cases were leprosy vaccine, measles vaccine and AC-Hib triple vaccine, while the top three reported cases were tetanus (acellular) vaccine, varicella vaccine and leprosy vaccine; clinical diagnosis of fever/swelling/induration-based general reaction accounted for 97.22%, allergic rash-based abnormal reaction accounted for 1.67%.Conclusion The incidence of AEFI in Hexi District of Tianjin from 2018 to 2020 is low, the AEFI monitoring system runs normally, and the vaccine safety is good. However, it is still necessary to strengthen the training of AEFI, improve the communication ability with parents and the level of response processing, so as to reduce the negative impact.

参考文献/References:

[1]WHO.Global manual on surveillance of adverse events following immunization[M].Geneva,Switzerland:WHO Document Production Services,2016.[2]邸明芝,黄辉,翟力军,等.北京某中学学生白破疫苗接种反应流行病学调查[J].中国学校卫生,2001,32(5):633.[3]范张洁,李锋,韩同武.2018年郑州市疑似预防接种异常反应的监测分析[J].河南预防医学杂志,2020,31(5):398-402.[4]陈敏,梁亚琼,徐鹭,等.2013-2016 年南京市疑似预防接种异常反应监测分析[J].现代预防医学,2017,44(23):4284-4286.[5]赵风林,运玉霞,聂占普,等.2017-2019年河南省濮阳市疑似预防接种异常反应监测分析[J].河南预防医学杂志,2021,32(7):540-543.[6]胡惠丽.疫苗接种不良反应的定义和分类[J].中华儿科杂志,2020,58(10):864-866.[7]彭时辉,文海蓉,许波,等.275例吸附无细胞百白破疫苗疑似预防接种异常反应病例的流行病学分析[J].现代预防医学,2016,43(18):3413-3415,3456.[8]刘玉霞,刘玉琳.不同剂次百白破疫苗接种后发生疑似预防接种反应的分析[J].河北医药,2016,37(23):3631-3632.[9]丁春燕.全国性预防接种异常反应补偿制度之建立:基于不同地方补偿的比较分析[J].中国卫生经济,2018,37(11):5-8.[10]王伟,李永成.2015-2018年天津市疑似预防接种异常反应监测分析[J].现代预防医学,2019,10(9):144-146.[11]房云霞,王金柱.2013年天津市河东区疑似预防接种异常反应监测分析[J].医学动物防制,2015,31(10):1128-1130. [12]钟运英.影响城市流动人口儿童预防接种因素途径分析[J].中国妇幼健康研究,2016,27(2):313－314.[13]王燕,王长双,肖占沛,等.河南省学龄前儿童家长预防接种知识知晓情况及影响因素分析[J].中国妇幼保健,2016,30(32):5630－5633.[14]贺皆晓,袁兆虎,周印,等.2016 年镇江市疑似预防接种异常反应监测结果[J].职业与健康,2017,933(18):2534-2536.[15]许涤沙,李克莉,武文娣,等.中国2016年疑似预防接种异常反应监测数据分析[J].中国疫苗和免疫,2018,24(3):299－309,322.[16]Fei L,Peng Z.No-Fault Compensation for Adverse Events Following Immunization: A Review of Chinese Law And Practice[J].Medical law review,2017,25(1):99-114[17]符丽英.流动儿童家长预防接种知识认知度及其影响因素研究[J]中国妇幼保健,2017,32(1):131-133.[18]杨配英.疫苗接种不良反应原因及预防对策分析[J].中外医学研究,2017,7(5):111-112.[19]中国疾控中心.中国疾控中心发布我国新冠疫苗接种不良反应监测情况,共31434例[J].现代医院,2021,21(6):884. [20]王淼,孙炜玮,李克莉,等.2015-2019年中国卡介苗疑似预防接种异常反应监测[J].中国疫苗和免疫,2021,26(10):242-245.

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更新日期/Last Update: 1900-01-01