[1]邵菁菁.西帕依固龈液联合西地碘含片对慢性牙周炎伴牙列缺损患者牙周健康指标的影响[J].医学信息,2022,35(11):138-140.[doi:10.3969/j.issn.1006-1959.2022.11.036]
　SHAO Jing-jing.Effect of Xipayi Mouth Rinse Fluid Combined with Cydiodine Buccal Tablets on Periodontal Health Indexes in Patients with Chronic Periodontitis and Dentition Defect[J].Medical Information,2022,35(11):138-140.[doi:10.3969/j.issn.1006-1959.2022.11.036]
点击复制

西帕依固龈液联合西地碘含片对慢性牙周炎伴牙列缺损患者牙周健康指标的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年11期
页码:
138-140
栏目:
论著
出版日期:
2022-06-01

文章信息/Info

Title:
Effect of Xipayi Mouth Rinse Fluid Combined with Cydiodine Buccal Tablets on Periodontal Health Indexes in Patients with Chronic Periodontitis and Dentition Defect
文章编号:
1006-1959（2022）11-0138-03
作者:
邵菁菁
（启东市人民医院口腔科，江苏 启东 226200）
Author(s):
SHAO Jing-jing
(Department of Stomatology,Qidong People’s Hospital,Qidong 226200,Jiangsu,China)
关键词:
慢性牙周炎; 牙列缺损; 西帕依固龈液; 西地碘含片; 牙周健康; 炎性因子
Keywords:
Chronic periodontitis; Dentition defect; Xipayi mouth rinse fluid; Cydiodine buccal tablets; Periodontal health; Inflammatory factors
分类号:
R988.2
DOI:
10.3969/j.issn.1006-1959.2022.11.036
文献标志码:
A
摘要:
目的 探讨慢性牙周炎伴牙列缺损患者联合应用西帕依固龈液与西地碘含片治疗的效果，以及其对牙周健康指标和炎性因子水平的影响。方法 选择2019年1月-2020年12月启东市人民医院口腔科收治的110例慢性牙周炎伴牙列缺损患者，采用随机数字表法分为试验组和对照组，每组55例。对照组使用西地碘含片治疗，试验组在此基础上联合西帕依固龈液治疗。比较两组牙周健康指标、炎性因子水平、临床疗效及用药安全性。结果 治疗14 d后，试验组牙周探诊深度（PD）、菌斑指数（PLI）、龈沟出血指数（SBI）、牙龈指数（GI）、龈沟液量（GCFV）、白介素-１β（IL-１β）、超敏-C反应蛋白（hs-CRP）及IL-8均低于对照组，差异有统计学意义（P＜0.05）；试验组总有效率为94.55%，高于对照组的78.18%，差异有统计学意义（P＜0.05）；试验组不良反应发生率为12.73%，低于对照组的9.09%，但组间比较，差异无统计学意义（P＞0.05）。结论 慢性牙周炎伴牙列缺损患者联合应用西帕依固龈液与西地碘含片治疗效果确切，可降低牙周炎性因子水平，恢复牙周健康，且用药安全性较高。
Abstract:
Objective To investigate the effect of combined application of Xipayi mouth rinse fluid and cydiodine buccal tablets in the treatment of patients with chronic periodontitis and dentition defect, and its influence on periodontal health indicators and inflammatory factor levels.Methods A total of 110 patients with chronic periodontitis and dentition defect admitted to Department of Stomatology, Qidong People’s Hospital from January 2019 to December 2020 were randomly divided into experimental group and control group, with 55 cases in each group. The control group was treated with cydiodine buccal tablets, and the experimental group was treated with Xipayi mouth rinse fluid on the basis of the control group. Periodontal health indicators, inflammatory factor levels, clinical efficacy and medication safety were compared between the two groups.Results After 14 days of treatment, the periodontal probing depth (PD), plaque index (PLI), sulcus bleeding index (SBI), gingival index (GI), gingival crevicular fluid volume (GCFV), interleukin-1β (IL-1β), high-sensitivity c-reactive protein (hs-CRP) and IL-8 in the experimental group were lower than those in the control group, and the difference was statistically significant (P＜0.05). The total effective rate of the experimental group was 94.55%, which was higher than 78.18% of the control group, and the difference was statistically significant (P＜0.05). The incidence of adverse reactions in the experimental group was 12.73%, which was lower than 9.09% in the control group, but there was no significant difference between the two groups (P>0.05).Conclusion The combination of Xipayi mouth rinse fluid and cydiodine buccal tablets in the treatment of patients with chronic periodontitis and dentition defect is effective, which can reduce the level of periodontitis factor, restore periodontal health, and have high medication safety.

参考文献/References:

[1]马冲,于寰,马勇强,等.牙周再生术治疗慢性牙周炎不同程度骨缺损的疗效评价[J].牙体牙髓牙周病学杂志,2018,28(8):455-460.[2]Stoica AM,Stoica OE,Ivacson CK,et al.Contribution to the study of improving the aesthetics of the smile by repairing and reshaping the incisors with composite materials[J].Acta Stomatologica Marisiensis Journal,2021,4(1):25-30.[3]Kothari SF,Nascimento GG,Jakobsen MB,et al.Periodontitis and orofacial health-related systemic impairment in Patients with brain injury:a factor analysis approach[J].Brain Inj,2021,35(1):96-102.[4]蔡敏.西地碘含片联合透明质酸凝胶对慢性牙周炎的治疗价值分析[J].中国药物与临床,2021,21(8):1316-1318.[5]潘春玲,赵海礁,宋佳,等.西地碘含片联合透明质酸凝胶辅助治疗中、重度慢性牙周炎临床疗效观察[J].中国实用口腔科杂志,2017,10(11):666-669.[6]中华口腔医学会牙周病学专业委员会.口腔诊疗中的牙周基本检查评估规范[J].中华口腔医学杂志,2021,56(3):238-243.[7]宁海燕,梁斌,梁扬师.西帕依固龈液联合牙周基础疗法治疗慢性牙周炎的临床观察[J].徐州医科大学学报,2019,39(7):541-543.[8]Balogun AO,Taiwo JO,Opeodu OI,et al.Impact of Non-Surgical Periodontal Therapy on the Salivary Levels of Tissue Inhibitor of Metalloprot einse-1 (TIMP-1) in Patients with Chronic Periodontitis:A Third World Experience[J].Open Journal of Stomatology,2021,11(5):11.[9]宁海燕,梁斌,梁扬师.西帕依固龈液含漱或冲洗辅助牙周基础治疗对牙周炎疗效的对比研究[J].实用口腔医学杂志,2020,36(2):312-316.[10]张建霞,辛越红,路丽,等.西帕依固龈液冲洗联合超声龈下刮治牙周炎疗效观察[J].中国中西医结合杂志,2018,38(8):945-949.[11]刘春子,潘艳,米宏图.西帕依固龈液漱口结合牙周基础治疗对糖尿病合并牙周炎患者的疗效观察[J].实用口腔医学杂志,2020,36(4):605-608.[12]Lamers S,Feng Q,Cheng Y,et al.Structural and kinetic characterization of Porphyromonas gingivalis glutaminyl cyclase[J].Biological Chemistry,2021,402(7):759-768.[13]王丽,陈贤,于钦,等.西帕依固龈液联合米诺环素对局限型侵袭性牙周炎牙周致病菌的作用分析[J].口腔材料器械杂志,2019,28(4):219-223.[14]朱姗姗,王爽.西帕依固龈液联合牙周治疗对妊娠期牙周炎的效果观察[J].中国医药,2018,13(4):597-600.[15]朱成英,潘国燕.益肾坚骨汤配合米诺环素与西帕依固龈液治疗局限型侵袭性牙周炎的疗效研究[J].中国美容医学,2018,27(8):81-83,138.[16]陈飞,焦鹏,车鸿泽,等.中药双黄补联合西帕依固龈液对种植体周围炎患者牙周炎症的改善作用及其临床意义[J].吉林大学学报(医学版),2017,43(6):1226-1230.[17]沈英.牙周炎与代谢综合征的相关性及西帕依固龈液疗效观察[J].新中医,2016,48(6):173-175.[18]肖兵,姚永泽,张辉,等.西帕依固龈液联合牙周基础治疗对2型糖尿病并发牙周炎患者的临床效果分析[J].中国医药,2020,15(2):248-250.[19]彭冬,邢乐君.一清片联合西地碘含片治疗重度慢性牙周炎的临床研究[J].现代药物与临床,2019,34(11):3384-3387.[20]王丽,陈贤,于钦,等.西帕依固龈液联合米诺环素治疗牙周炎的临床效果观察[J].解放军医药杂志,2020,32(6):69-72,85.

相似文献/References:

[1]赵 敏,杨长怡,郭晓倩,等.激光治疗中重度慢性牙周炎的临床效果评价[J].医学信息,2018,31(05):93.[doi:10.3969/j.issn.1006-1959.2018.05.030]
　ZHAO Min,YANG Chang-yi,GUO Xiao-qian,et al.Clinical Evaluation of Laser Treatment for Moderate and Severe Chronic Periodontitis[J].Medical Information,2018,31(11):93.[doi:10.3969/j.issn.1006-1959.2018.05.030]
[2]褚福行,李珊珊,李思琪,等.慢性牙周炎伴肥胖患者血清中IL-6、IL-18表达水平的研究[J].医学信息,2019,32(01):92.[doi:10.3969/j.issn.1006-1959.2019.01.028]
　CHU Fu-xing,LI Shan-shan,LI Si-qi,et al.Study on the Expression Levels of IL-6 and IL-18 in Serum of Patients with Chronic Periodontitis and Obesity[J].Medical Information,2019,32(11):92.[doi:10.3969/j.issn.1006-1959.2019.01.028]
[3]李庆华,胡运苑,黄 玲.牙周根管超声治疗仪应用于慢性牙周炎的临床疗效[J].医学信息,2019,32(09):119.[doi:10.3969/j.issn.1006-1959.2019.09.039]
　LI Qing-hua,HU Yun-yuan,HUANG Ling.Clinical Efficacy of Periodontal Root Canal Ultrasound Therapy Instrument in Patients with Chronic Periodontitis[J].Medical Information,2019,32(11):119.[doi:10.3969/j.issn.1006-1959.2019.09.039]
[4]杨随兴.盐酸米诺环素软膏治疗中重度慢性牙周炎的临床疗效[J].医学信息,2019,32(18):153.[doi:10.3969/j.issn.1006-1959.2019.18.053]
　YANG Sui-xing.Clinical Efficacy of Minocycline Hydrochloride Ointment in the Treatment of Moderate to Severe Chronic Periodontitis[J].Medical Information,2019,32(11):153.[doi:10.3969/j.issn.1006-1959.2019.18.053]
[5]刘 艳,格根塔娜.细胞因子在慢性牙周炎骨吸收中的作用[J].医学信息,2021,34(21):36.[doi:10.3969/j.issn.1006-1959.2021.21.008]
　LIU Yan,GEGEN Ta-na.Role of Cytokines in Bone Resorption of Chronic Periodontitis[J].Medical Information,2021,34(11):36.[doi:10.3969/j.issn.1006-1959.2021.21.008]
[6]柯秀平,宋冠杰,高丽荣.牙周基础治疗联合正畸对慢性牙周炎伴前牙病理性移位的效果[J].医学信息,2021,34(21):131.[doi:10.3969/j.issn.1006-1959.2021.21.036]
　KE Xiu-ping,SONG Guan-jie,GAO Li-rong.Effect of Periodontal Basic Therapy Combined with Orthodontic Treatment on Chronic Periodontitis with Pathological Displacement of Anterior Teeth[J].Medical Information,2021,34(11):131.[doi:10.3969/j.issn.1006-1959.2021.21.036]
[7]张 力.牙周基础治疗慢性牙周炎的疗效及其对炎性因子的影响[J].医学信息,2020,33(07):107.[doi:10.3969/j.issn.1006-1959.2020.07.031]
　ZHANG Li.Periodontal Treatment of Chronic Periodontitis Patients and Its Effect on Inflammatory Factors[J].Medical Information,2020,33(11):107.[doi:10.3969/j.issn.1006-1959.2020.07.031]
[8]陈济贤.半导体激光联合牙周基础治疗对慢性牙周炎患者的临床疗效[J].医学信息,2022,35(20):90.[doi:10.3969/j.issn.1006-1959.2022.20.023]
　CHEN Ji-xian.Clinical Effect of Semiconductor Laser Combined with Periodontal Basic Treatment on Patients with Chronic Periodontitis[J].Medical Information,2022,35(11):90.[doi:10.3969/j.issn.1006-1959.2022.20.023]
[9]刘 伟.盐酸米诺环素联合替硝唑治疗慢性牙周炎患者的疗效[J].医学信息,2021,34(06):163.[doi:10.3969/j.issn.1006-1959.2021.06.043]
　LIU Wei.Efficacy of Minocycline Hydrochloride Combined with Tinidazole in the Treatment of Patients with Chronic Periodontitis[J].Medical Information,2021,34(11):163.[doi:10.3969/j.issn.1006-1959.2021.06.043]
[10]蔡芸舟,李熠洁,杨艳青,等.种植修复的发展现状与不足[J].医学信息,2021,34(09):37.[doi:10.3969/j.issn.1006-1959.2021.09.009]
　CAI Yun-zhou,LI Yi-jie,YANG Yan-qing,et al.Development Status and Shortcomings of Planting Restoration[J].Medical Information,2021,34(11):37.[doi:10.3969/j.issn.1006-1959.2021.09.009]

更新日期/Last Update: 1900-01-01