[1]褚春沐.β-七叶皂苷钠联合甘油果糖对脑出血患者神经功能恢复的影响[J].医学信息,2022,35(11):147-149.[doi:10.3969/j.issn.1006-1959.2022.11.039]
　CHU Chun-mu.Effect of Sodium Aescinate Combined with Glycerol Fructose on Neurological Function Recovery in Patients with Cerebral Hemorrhage[J].Medical Information,2022,35(11):147-149.[doi:10.3969/j.issn.1006-1959.2022.11.039]
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β-七叶皂苷钠联合甘油果糖对脑出血患者神经功能恢复的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年11期
页码:
147-149
栏目:
论著
出版日期:
2022-06-01

文章信息/Info

Title:
Effect of Sodium Aescinate Combined with Glycerol Fructose on Neurological Function Recovery in Patients with Cerebral Hemorrhage
文章编号:
1006-1959（2022）11-0147-03
作者:
褚春沐
（佳木斯市中心医院神经内科，黑龙江 佳木斯 154002）
Author(s):
CHU Chun-mu
(Department of Neurology,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
β-七叶皂苷钠; 甘油果糖; 脑出血; 神经功能
Keywords:
Sodium aescinate; Glycerol fructose; Cerebral hemorrhage; Neurological function
分类号:
R743.34
DOI:
10.3969/j.issn.1006-1959.2022.11.039
文献标志码:
A
摘要:
目的 观察β-七叶皂苷钠联合甘油果糖治疗脑出血对患者神经功能恢复的影响。方法 选取2019年6月-2021年6月在我院治疗的72例脑出血患者为研究对象，采用随机数字表法分为对照组和观察组，各36例。对照组采用甘油果糖治疗，观察组在对照组基础上联合β-七叶皂苷钠治疗，比较两组治疗总有效率、脑水肿和血肿量、神经功能缺损评分（NIHSS）、日常生活能力评分（ADL）、颅内压降低起效时间及不良反应发生情况。结果 观察组总有效率为94.44%，高于对照组的83.33%（P＜0.05）；观察组脑水肿、血肿量均低于对照组（P＜0.05）；两组NIHSS评分均低于治疗前，ADL评分均高于治疗前，且观察组NIHSS评分低于对照组，ADL评分高于对照组（P＜0.05）；观察组颅内压降低起效时间短于对照组（P＜0.05）；两组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论 β-七叶皂苷钠联合甘油果糖治疗脑出血效果显著，可提高总有效率，减少脑水肿和血肿，降低神经功能缺损评分，提高患者日常生活能力，缩短颅内压降低起效时间，不良反应少，是一种安全、有效的治疗方案。
Abstract:
Objective To observe the effect of sodium aescinate combined with glycerol fructose on the recovery of neurological function in patients with cerebral hemorrhage.Methods A total of 72 patients with cerebral hemorrhage treated in our hospital from June 2019 to June 2021 were selected as the research subjects. They were divided into control group and observation group by random number table method, with 36 cases in each group. The control group was treated with glycerol fructose, and the observation group was treated with sodium aescinate on the basis of the control group. The total effective rate, cerebral edema and hematoma volume, neurological deficit score (NIHSS), daily living ability score (ADL), intracranial pressure reduction onset time and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.44%, which was higher than 83.33% of the control group (P<0.05). The cerebral edema and hematoma volume in the observation group were lower than those in the control group (P<0.05). NIHSS scores of the two groups were lower than those before treatment, and ADL scores were higher than those before treatment,meanwhile NIHSS scores of the observation group were lower than those of the control group, and ADL scores were higher than those of the control group (P<0.05). The onset time of intracranial pressure reduction in the observation group was shorter than that in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion Sodium aescinate combined with glycerol fructose is effective in the treatment of cerebral hemorrhage, which can improve the total effective rate, reduce cerebral edema and hematoma and neurological deficit score, improve the daily living ability, shorten the onset time of intracranial pressure and reduce adverse reactions. It is a safe and effective treatment.

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更新日期/Last Update: 1900-01-01