[1]王文建,王博韬,李昊辰,等.维生素D辅助股骨近端防旋髓内钉内固定治疗老年股骨转子间骨折的远期疗效观察[J].医学信息,2022,35(14):119-121.[doi:10.3969/j.issn.1006-1959.2022.14.029]
 WANG Wen-jian,WANG Bo-tao,LI Hao-chen,et al.Long-term Effect of Vitamin D Assisted Proximal Femoral Nail Anti-rotation Internal Fixation in the Treatment of Elderly Patients with Intertrochanteric Fracture of Femur[J].Medical Information,2022,35(14):119-121.[doi:10.3969/j.issn.1006-1959.2022.14.029]
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维生素D辅助股骨近端防旋髓内钉内固定治疗老年股骨转子间骨折的远期疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年14期
页码:
119-121
栏目:
药物与临床
出版日期:
2022-07-15

文章信息/Info

Title:
Long-term Effect of Vitamin D Assisted Proximal Femoral Nail Anti-rotation Internal Fixation in the Treatment of Elderly Patients with Intertrochanteric Fracture of Femur
文章编号:
1006-1959(2022)14-0119-03
作者:
王文建王博韬李昊辰
(天津市北辰中医医院骨伤科,天津 300000)
Author(s):
WANG Wen-jianWANG Bo-taoLI Hao-chenet al.
(Department of Orthopedics and Traumatology,Tianjin Beichen Hospital of Traditional Chinese Medicine,Tianjin 300000,China)
关键词:
维生素D股骨近端防旋髓内钉股骨转子间骨折
Keywords:
Vitamin DProximal femurAntirotation intramedullary nailIntertrochanteric fracture of femur
分类号:
R687.3
DOI:
10.3969/j.issn.1006-1959.2022.14.029
文献标志码:
A
摘要:
目的 观察维生素D辅助股骨近端防旋髓内钉内固定治疗老年股骨转子间骨折的远期疗效。方法 选取2018年4月-2021年1月在我院诊治的62例老年股骨转子间骨折患者为研究对象,采用随机数字表法分为对照组和观察组,各31例。对照组采用股骨近端防旋髓内钉内固定治疗,观察组在对照组基础上采用维生素D辅助治疗,比较两组骨折恢复优良率、Harris髋关节评分、血清骨形态发生蛋白质-7(BMP-7)和25-羟维生素D3[25(OH)D3]水平、并发症发生情况。结果 观察组治疗优良率为93.54%,高于对照组的83.87%,差异有统计学意义(P<0.05);两组治疗1、6个月后Harris评分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);两组治疗后血清BMP-7、25(OH)D3水平均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05);随访5个月,观察组并发症发生率为6.45%,低于对照组的16.13%,差异有统计学意义(P<0.05)。结论 维生素D辅助股骨近端防旋髓内钉内固定治疗老年股骨转子间骨折优良率高,可提高患者Harris评分,改善血清BMP-7和25(OH)D3水平,且远期并发症发生率低,疗效较好。
Abstract:
Objective To observe the long-term effect of vitamin D assisted proximal femoral nail anti-rotation internal fixation in the treatment of elderly patients with intertrochanteric fracture of femur.Methods A total of 62 elderly patients with intertrochanteric fracture of femur treated in our hospital from April 2018 to January 2021 were selected as the study subjects. They were divided into control group and observation group by random number table method, with 31 cases in each group. The control group was treated with proximal femoral nail anti-rotation internal fixation, and the observation group was treated with vitamin D adjuvant therapy on the basis of the control group. The excellent and good rate of fracture recovery, Harris hip score, serum bone morphogenetic protein-7 (BMP-7) and 25-hydroxyvitamin D3[25(OH)D3] levels, and complications were compared between the two groups.Results The excellent and good rate of treatment in the observation group was 93.54%, which was higher than 83.87% in the control group, and the difference was statistically significant (P<0.05). The Harris scores of the two groups after 1 and 6 months of treatment were higher than those before treatment, and those in the observation group were higher than the control group, the difference was statistically significant (P<0.05). The serum BMP-7 and 25(OH)D3 levels in the two groups after treatment were higher than those before treatment, and those in the observation group were higher than the control group, the differences were statistically significant (P<0.05). After five months of follow-up, the incidence of complications in the observation group was 6.45%, which was lower than 16.13% in the control group, and the difference was statistically significant (P<0.05).Conclusion The excellent and good rate of vitamin D-assisted proximal femoral nail anti-rotation internal fixation in the treatment of elderly patients with intertrochanteric fracture of femur is high, which can improve the Harris score of patients, improve the serum levels of BMP-7 and 25(OH)D3, and the incidence of long-term complications is low, and the curative effect is good.

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更新日期/Last Update: 1900-01-01