[1]吴忠亮,林 毅,张兴发.新辅助治疗后行结直肠癌根治术的患者术后并发症发生情况及预后预测因素分析[J].医学信息,2022,35(16):90-93.[doi:10.3969/j.issn.1006-1959.2022.16.021]
　WU Zhong-liang,LIN Yi,ZHANG Xing-fa.Analysis of Postoperative Complications and Prognostic Factors in Patients Undergoing Radical Resection of Colorectal Cancer After Neoadjuvant Therapy[J].Journal of Medical Information,2022,35(16):90-93.[doi:10.3969/j.issn.1006-1959.2022.16.021]
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新辅助治疗后行结直肠癌根治术的患者术后并发症发生情况及预后预测因素分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年16期
页码:
90-93
栏目:
论著
出版日期:
2022-08-15

文章信息/Info

Title:
Analysis of Postoperative Complications and Prognostic Factors in Patients Undergoing Radical Resection of Colorectal Cancer After Neoadjuvant Therapy
文章编号:
1006-1959（2022）16-0090-04
作者:
吴忠亮; 林 毅; 张兴发
（贵州医科大学第三附属医院胃肠外科，贵州 都匀 558000）
Author(s):
WU Zhong-liang; LIN Yi; ZHANG Xing-fa
(Department of Gastroenterology,the Third Affiliated Hospital of Guizhou Medical University,Duyun 558000,Guizhou,China)
关键词:
新辅助治疗; 结直肠癌根治术; 术后并发症
Keywords:
Neoadjuvant therapy; Radical resection for colorectal cancer; Postoperative complications
分类号:
R735.3+7
DOI:
10.3969/j.issn.1006-1959.2022.16.021
文献标志码:
A
摘要:
目的 分析新辅助治疗后行结直肠癌根治术的患者术后并发症发生情况及预后预测因素。方法 回顾性分析我院2018年1月-2021年12月收治86例结直肠癌患者的临床资料，所有患者均在接受新辅助治疗后行结直肠癌根治术，记录并发症发生情况将其分为并发症组和无并发症组，比较两组并发症发生情况、术后恢复情况及生活质量，分析影响患者预后的危险因素。结果 86例结直肠癌患者中，术后18例出现并发症，并发症发生率为20.93%；并发症组与无并发症组术后排气时间、进食时间比较，差异无统计学意义（P＞0.05）；并发症组住院时间高于无并发症组，差异有统计学意义（P＜0.05）；并发症组生活质量各个维度评分均低于无并发症组，差异有统计学意义（P＜0.05）；两组年龄、合并症、TNM分期、ASA评分比较，差异有统计学意义（P＜0.05）；两组性别、体重指数、肿瘤大小以及肿瘤位置比较，差异无统计学意义（P＞0.05）；多因素分析显示，年龄＞60岁、术前合并症、TNM分期以及ASA评分是新辅助治疗后行结直肠癌根治术患者预后的独立危险因素。结论 年龄、合并症、TNM分期、ASA评分是预测新辅助治疗后行结直肠癌根治术患者术后并发症的独立危险因素，临床中应重点关注此类患者，及时进行干预，从而避免并发症的发生，提高患者生活质量。
Abstract:
Objective To analyze the incidence of postoperative complications and prognostic factors in patients undergoing radical resection of colorectal cancer after neoadjuvant therapy.Methods The clinical data of 86 patients with colorectal cancer admitted to our hospital from January 2018 to December 2021 were retrospectively analyzed. All patients underwent radical resection of colorectal cancer after neoadjuvant therapy. The complications were recorded and divided into complication group and non-complication group. The incidence of complications, postoperative recovery and life treatment were compared between the two groups, and the risk factors affecting the prognosis of patients were analyzed.Results Among 86 patients with colorectal cancer, 18 cases had complications after operation, and the incidence of complications was 20.93%. There was no significant difference in postoperative exhaust time and eating time between the complication group and the non-complication group (P>0.05). The hospitalization time of the complication group was higher than that of the non-complication group, and the difference was statistically significant (P<0.05). The scores of all dimensions of quality of life in the complication group were lower than those in the non-complication group, and the difference was statistically significant (P<0.05). There were significant differences in age, complications, TNM stage and ASA score between the two groups (P<0.05). There was no significant difference in gender, body mass index, tumor size and tumor location between the two groups (P>0.05). Multivariate analysis showed that age > 60 years old, preoperative complications, TNM stage and ASA score were independent risk factors for the prognosis of patients undergoing radical resection of colorectal cancer after neoadjuvant therapy.Conclusion Age, comorbidities, TNM stage and ASA score are independent risk factors for predicting postoperative complications in patients undergoing radical resection of colorectal cancer after neoadjuvant therapy. Clinical attention should be paid to such patients, and timely intervention should be performed to avoid complications disease and improve the quality of life of patients.

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更新日期/Last Update: 1900-01-01