[1]艾 露.地塞米松联合庆大霉素在非哺乳期乳腺炎治疗中的应用[J].医学信息,2022,35(16):138-140.[doi:10.3969/j.issn.1006-1959.2022.16.035]
 AI Lu.Application of Dexamethasone Combined with Gentamicin in the Treatment of Non-lactating Mastitis[J].Journal of Medical Information,2022,35(16):138-140.[doi:10.3969/j.issn.1006-1959.2022.16.035]
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地塞米松联合庆大霉素在非哺乳期乳腺炎治疗中的应用()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年16期
页码:
138-140
栏目:
药物与临床
出版日期:
2022-08-15

文章信息/Info

Title:
Application of Dexamethasone Combined with Gentamicin in the Treatment of Non-lactating Mastitis
文章编号:
1006-1959(2022)16-0138-03
作者:
艾 露
(武宁县妇幼保健院妇产科,江西 武宁 332300)
Author(s):
AI Lu
(Department of Obstetrics and Gynecology,Wuning Maternal and Child Health Hospital,Wuning 332300,Jiangxi,China)
关键词:
地塞米松庆大霉素非哺乳期乳腺炎
Keywords:
DexamethasoneGentamicinNon-lactatingMastitis
分类号:
R655.8
DOI:
10.3969/j.issn.1006-1959.2022.16.035
文献标志码:
A
摘要:
目的 观察地塞米松联合庆大霉素在非哺乳期乳腺炎治疗中临床效果。方法 选取2020年6月-2021年6月在我院诊治的68例非哺乳期乳腺炎患者为研究对象,采用随机数字表法分为对照组和观察组,每组34例。对照组给予庆大霉素治疗,观察组在对照组基础上给予地塞米松治疗,比较两组临床治疗疗效、肿块大小、疼痛评分(VAS)、血清炎性因子水平、不良反应发生率及复发率。结果 观察组治疗总有效率为91.18%,高于对照组的82.35%(P<0.05);两组治疗后肿块面积均小于治疗前,且观察组小于对照组(P<0.05);两组治疗后疼痛评分均低于治疗前,且观察组低于对照组(P<0.05);两组治疗后白细胞计数(WBC)、C反应蛋白(CRP)均低于治疗前,且观察组低于对照组(P<0.05);观察组不良反应发生率为5.88%,与对照组的8.82%比较,差异无统计学意义(P>0.05);随访2个月,观察组复发率为5.88%,低于对照组的17.65%(P<0.05)。结论 非哺乳期乳腺炎采用地塞米松联合庆大霉素治疗,可提高治疗效果,显著缩小肿块面积,降低疼痛评分、炎症因子水平、复发率,且不会增加不良反应,具有临床应用价值。
Abstract:
Objective To observe the clinical effect of dexamethasone combined with gentamicin in the treatment of non-lactating mastitis.Methods A total of 68 patients with non-lactating mastitis who were treated in our hospital from June 2020 to June 2021 were selected as the research objects. They were divided into control group and observation group by random number table method, with 34 cases in each group. The control group was treated with gentamicin, and the observation group was treated with dexamethasone on the basis of the control group. The clinical efficacy, tumor size, pain score (VAS), serum inflammatory factor level, incidence of adverse reactions and recurrence rate were compared between the two groups.Results The total effective rate of the observation group was 91.18%, which was higher than 82.35% of the control group (P<0.05). The mass area of the two groups after treatment was less than that before treatment, and the observation group was less than the control group (P<0.05). The pain scores of the two groups after treatment were lower than those before treatment, and the observation group was lower than the control group (P<0.05). The white blood cell count (WBC) and C-reactive protein (CRP) of the two groups after treatment were lower than those before treatment, and the observation group was lower than the control group (P<0.05). The incidence of adverse reactions in the observation group was 5.88%, which was compared with 8.82% in the control group, the difference was not statistically significant (P>0.05). After 2 months of follow-up, the recurrence rate in the observation group was 5.88%, which was lower than 17.65% in the control group (P<0.05).Conclusion The use of dexamethasone combined with gentamicin in the treatment of non-lactating mastitis can improve the therapeutic effect, significantly reduce the tumor area, reduce the pain score, inflammatory factor level, and recurrence rate, without increasing adverse reactions, and has obvious clinical application value.

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更新日期/Last Update: 1900-01-01