[1]周宏芳.欣母沛对高危孕妇凝血功能指标及产后出血风险的影响[J].医学信息,2022,35(18):109-111.[doi:10.3969/j.issn.1006-1959.2022.18.029]
　ZHOU Hong-fang.Effect of Hemabate on Coagulation Function Indexes and Postpartum Hemorrhage Risk in High Risk Pregnant Women[J].Journal of Medical Information,2022,35(18):109-111.[doi:10.3969/j.issn.1006-1959.2022.18.029]
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欣母沛对高危孕妇凝血功能指标及产后出血风险的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年18期
页码:
109-111
栏目:
药物与临床
出版日期:
2022-09-15

文章信息/Info

Title:
Effect of Hemabate on Coagulation Function Indexes and Postpartum Hemorrhage Risk in High Risk Pregnant Women
文章编号:
1006-1959（2022）18-0109-03
作者:
周宏芳
（上饶市广信区人民医院妇产科，江西 上饶 334100）
Author(s):
ZHOU Hong-fang
(Department of Obstetrics and Gynecology,Guangxin District People’s Hospital,Shangrao 334100,Jiangxi,China)
关键词:
高危孕妇; 凝血功能; 产后出血; 欣母沛; 血液流变学
Keywords:
High-risk pregnant women; Coagulation function; Postpartum hemorrhage; Hemabate; Hemorheology
分类号:
R714.46+1
DOI:
10.3969/j.issn.1006-1959.2022.18.029
文献标志码:
A
摘要:
目的 研究欣母沛对高危孕妇凝血功能指标及产后出血风险的影响。方法 选取2019年1月-2021年1月我院收治的60例高危孕妇，采用随机数字表法分为对照组和观察组，各30例。对照组采用缩宫素治疗，观察组在对照组基础上应用欣母沛治疗，比较两组出血情况、凝血功能[血红蛋白（Hb）、红细胞压积（HCT）、血小板（PLT）]、血液流变学指标（高切全血黏度、中切全血黏度、低切全血黏度）、并发症及产妇临床结局。结果 观察组产后2、24 h出血量及产后出血发生率均小于对照组（P＜0.05）；两组产后24 h Hb、HCT、PLT低于产前，但观察组高于对照组（P＜0.05）；观察组产后24 h高切全血黏度、中切全血黏度、低切全血黏度均低于对照组（P＜0.05），而与产前比较，差异无统计学意义（P＞0.05）；两组并发症发生率比较，差异无统计学意义（P＞0.05）；观察组输血率为3.33%，低于对照组的16.67%（P＜0.05）。结论 欣母沛可减少高危孕妇产后出血量，降低其产后出血风险，改善产妇的凝血功能，且不会引起血液流变学指标及并发症风险的增加，有利于临床结局的改善。
Abstract:
Objective To study the effect of hemabate on coagulation function indexes and postpartum hemorrhage risk in high-risk pregnant women.Methods Sixty high-risk pregnant women admitted to our hospital from January 2019 to January 2021 were selected and divided into a control group and an observation group according to the random number table method, with 30 cases in each group. The control group was treated with oxytocin, and the observation group was treated with hemabate on the basis of the control group. The bleeding, coagulation function [hemoglobin (Hb), hematocrit (HCT), platelet (PLT)], hemorheological indexes, complications and maternal clinical outcomes were compared between the two groups.Results The amount of bleeding at 2 and 24 hours after delivery and the incidence of postpartum hemorrhage in the observation group were lower than those in the control group (P<0.05). The Hb, HCT and PLT of the two groups at 24 h after delivery were lower than those before delivery, but the observation group was higher than the control group (P<0.05). The whole blood high shear viscosity, whole blood middle shear viscosity and whole Blood low shear viscosity of the observation group at 24 h postpartum were lower than those of the control group (P<0.05), but there was no significant difference compared with prenatal (P>0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). The blood transfusion rate of the observation group was 3.33%, which was lower than 16.67% of the control group (P<0.05).Conclusion Hemabate can reduce the amount of postpartum hemorrhage in high-risk pregnant women, reduce the risk of postpartum hemorrhage, improve maternal coagulation function, and will not increase the risk of hemorheology and complications, is conducive to the improvement of clinical outcomes.

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更新日期/Last Update: 1900-01-01