[1]陈 鑫,李 虹,周绍鹏,等.加味二陈汤辨证治疗小儿咳嗽的临床疗效观察[J].医学信息,2022,35(18):135-137.[doi:10.3969/j.issn.1006-1959.2022.18.037]
 CHEN Xin,LI Hong,ZHOU Shao-peng,et al.Clinical Observation on Treatment of Infantile Cough with Jiawei Erchen Decoction[J].Journal of Medical Information,2022,35(18):135-137.[doi:10.3969/j.issn.1006-1959.2022.18.037]
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加味二陈汤辨证治疗小儿咳嗽的临床疗效观察()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年18期
页码:
135-137
栏目:
中医中药
出版日期:
2022-09-15

文章信息/Info

Title:
Clinical Observation on Treatment of Infantile Cough with Jiawei Erchen Decoction
文章编号:
1006-1959(2022)18-0135-03
作者:
陈 鑫李 虹周绍鹏
(上高县人民医院中医科,江西 上高 336400)
Author(s):
CHEN XinLI HongZHOU Shao-penget al.
(Department of Traditional Chinese Medicine,Shanggao County People’s Hospital,Shanggao 336400,Jiangxi,China)
关键词:
小儿咳嗽加味二陈汤睡眠质量
Keywords:
Children’s coughJiawei Erchen decoctionSleep quality
分类号:
R272
DOI:
10.3969/j.issn.1006-1959.2022.18.037
文献标志码:
A
摘要:
目的 探讨加味二陈汤辨证治疗小儿咳嗽的临床疗效。方法 选取2019年1月-2020年5月在我院门诊的小儿咳嗽病例50例,采用随机数字表法将其分为试验组(25例)和对照组(25例)。试验组给予加味二陈汤进行辨证治疗,对照组给予头孢克洛颗粒联合氨溴索口服液进行治疗。比较两组临床疗效、病程、不良反应发生情况、肺通气功能、睡眠质量、免疫球蛋白E(IgE)水平及嗜酸性粒细胞(EOS)水平。结果 试验组总有效率为96.00%,高于对照组的76.00%(P<0.05);试验组病程为(10.42±2.83)d,短于对照组的(12.06±1.85)d(P<0.05);试验组不良反应总发生率为4.00%,低于对照组的24.00%(P<0.05);试验组治疗后IgE、EOS水平低于对照组,FEV1及睡眠质量改善优于对照组(P<0.05)。结论 应用加味二陈汤辨证治疗小儿咳嗽疗效确切、安全性高、且病程缩短、患儿肺通气功能及睡眠质量得到改善。
Abstract:
Objective To explore the clinical effect of Jiawei Erchen decoction in the dialectical treatment of infantile cough.Methods Fifty cases of pediatric cough in our hospital from January 2019 to May 2020 were selected and divided into experimental group (25 cases) and control group (25 cases) by random number table. The experimental group was treated with Jiawei Erchen decoction, and the control group was treated with Cefaclor granules combined with Ambroxol Oral Solution. The clinical efficacy, course of disease, adverse reactions, pulmonary ventilation function, sleep quality, immunoglobulin E (IgE) level and eosinophil (EOS) level were compared between the two groups.Results The total effective rate of the experimental group was 96.00%, which was higher than 76.00% of the control group(P<0.05). The duration of disease in the experimental group was (10.42±2.83) d, which was shorter than that in the control group (12.06±1.85) d(P<0.05). The total incidence of adverse reactions in the experimental group was 4.00%, which was lower than 24.00% in the control group(P<0.05). After treatment, the levels of IgE and EOS in the experimental group were lower than those in the control group, and the FEV1 and sleep quality were better than those of the control group(P<0.05).Conclusion The application of Jiawei Erchen decoction in the dialectical treatment of infantile cough is effective and safe, and the course of disease is shortened, the pulmonary ventilation function and sleep quality of children are improved.

参考文献/References:

[1]中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南(草案)[J].中华结核和呼吸杂志,2005,28(11):738-744.[2]吴丽洁.孟鲁司特钠治疗小儿咳嗽变异型哮喘的临床疗效[J].临床合理用药杂志,2020,13(36):74-75.[3]朱霞,黄东生,张伟令.氯雷他定联合孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床疗效[J].北京医学,2020,42(11):1101-1103.[4]刘新举,聂艳晴,熊志强.宣肺化痰丸联合西药治疗风邪伏肺型咳嗽变异性哮喘临床观察[J].光明中医,2020,35(10):1537-1539.[5]董尚娟,史利卿,季坤.祛风宣肺方治疗咳嗽变异性哮喘的临床疗效观察[J].现代中医临床,2019,26(4):6-9.[6]徐超极.基于Th1/Th2失衡机制观察儿童咳嗽变异性哮喘中医分期治疗的临床疗效[D].福州:福建中医药大学,2018.[7]江南芳.定喘汤加减联合孟鲁司特钠治疗小儿咳嗽变异性哮喘的临床疗效[J].临床合理用药杂志,2020,13(25):96-97.[8]龙世德,钟成祥,黄焕祥.匹多莫德联合孟鲁司特治疗小儿咳嗽变异性哮喘的临床研究[J].黑龙江医药,2020,33(5):1034-1035.[9]刘文彦.自拟宁肺汤治疗小儿慢性咳嗽肺脾气虚型的临床研究[D].北京:北京中医药大学,2016.[10]Tan F,Wang L,Ma M.Clinical effect observation on mechanical vibration sputum drainage in the treatment of children with wet cough[J].Chinese Community Doctors,2017,7(3):278-292.[11]钟帼钰,陈德晖,李谨瑛.布地奈德和利巴韦林雾化吸入治疗儿童咳嗽的临床观察[J].中国热带医学,2017(4):568-570.[12]陈灏健.雾化吸入治疗儿童咳嗽的临床疗效分析[J].现代中西医结合杂志,2010,19(20):2494-2496.[13]Sharma U,Karishma,Pandey D,et al.Shringyadi Leha-An Ayurvedic Remedial Formulation For Infantile Cough: A Review[J].International Journal of Ayurvedic and Herbal Medicine,2020,10(4):3825-3831.[14]范荣荣.温肺疏风方治疗咳嗽变异性哮喘的临床疗效评价及分子机制研究[D].广州:广州中医药大学,2019.[15]解玉东.气道过敏反应测试系统在慢性咳嗽诊断中的意义[D].新乡:新乡医学院,2017.[16]张玉琴,袁源.两种方式注射替罗非班对急诊PCI患者预后的影响[J].中国医学工程,2020,28(12):63-66.[17]周平生.基于数据挖掘的半夏及其经方研究[D].南昌:江西中医药大学,2019.[18]武鑫,王光恩.橘红与化橘红的性状鉴别与临床合理应用[J].内蒙古中医药,2017,36(19):109-110.[19]王伟,林宇城,王玉兰,等.金银花茯苓提取物对小鼠免疫功能的在体调控作用[J].沈阳药科大学学报,2022,39(1):52-59.[20]李文静,刘德山.刘德山教授运用炙甘草汤加减择时用药治疗心悸的临证经验[J].河北中医,2018,40(12):1768-1771.[21]周容戎,安学东,赵生慧.黄芪、陈皮、炒白术补中益气治疗脆性糖尿病中气亏虚证经验——仝小林三味小方撷萃[J].吉林中医药,2020,40(12):1541-1543.

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更新日期/Last Update: 1900-01-01