[1]屈玉华,陈凤鸣,范润平.嗜麦芽窄食单胞菌感染患者死亡危险因素的Meta分析[J].医学信息,2022,35(23):69-75.[doi:10.3969/j.issn.1006-1959.2022.23.011]
　QU Yu-hua,CHEN Feng-ming,FAN Run-ping.Meta-analysis of Risk Factors for Death in Patients with Stenotrophomonas Maltophilia Infection[J].Journal of Medical Information,2022,35(23):69-75.[doi:10.3969/j.issn.1006-1959.2022.23.011]
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嗜麦芽窄食单胞菌感染患者死亡危险因素的Meta分析()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年23期
页码:
69-75
栏目:
论著
出版日期:
2022-12-01

文章信息/Info

Title:
Meta-analysis of Risk Factors for Death in Patients with Stenotrophomonas Maltophilia Infection
文章编号:
1006-1959（2022）23-0069-07
作者:
屈玉华; 陈凤鸣; 范润平
（成都中医药大学附属医院肛肠科，四川 成都 610072）
Author(s):
QU Yu-hua; CHEN Feng-ming; FAN Run-ping
(Department of Anorectal,Hospital of Chengdu University of TCM,Chengdu 610072,Sichuan,China)
关键词:
嗜麦芽窄食单胞菌; 感染; 死亡; 危险因素
Keywords:
Stenotrophomonas maltophilia; Infection; Death; Risk factor
分类号:
R378.99
DOI:
10.3969/j.issn.1006-1959.2022.23.011
文献标志码:
A
摘要:
目的 通过Meta分析明确嗜麦芽窄食单胞菌感染患者的死亡危险因素。方法 计算机检索PubMed、Embase、Web of Science、中国期刊全文数据库（CNKI）、万方医学数据库（WanFang Data）、中国生物医学文献数据库（CBM）中关于嗜麦芽窄食单胞菌感染患者死亡危险因素的研究文献，由2名研究人员按照标准独立完成文献筛选、资料提取和文献质量评价。应用RevMan5.3软件对纳入文献进行Meta分析。结果 最终纳入16篇文献，样本量为1449例，共纳入50个危险因素。Meta分析显示：急性生理与慢性健康状况评分Ⅱ（APACHEⅡ）、留置中心静脉导管、多器官功能障碍综合征（MODS）、序贯器官衰竭评分（SOFA）＞6分、留置鼻胃管、Charlson合并症指数（CCI）、机械通气、中性粒细胞减少症、肠外营养、留置尿管、手术、使用碳青霉烯类抗生素、糖尿病、使用糖肽类抗生素、感染性休克、血小板减少症、恶性血液病、住ICU是嗜麦芽窄食单胞菌感染患者死亡的独立危险因素。结论 嗜麦芽窄食单胞菌感染患者死亡危险因素较多，但部分影响因素指标的文献数量较少，无法明确其与SMA感染后死亡的相关性，尚需要大样本、高质量的前瞻性研究进一步明确嗜麦芽窄食单胞菌感染患者死亡危险因素。
Abstract:
Objective To identify the risk factors of death in patients with Stenotrophomonas maltophilia infection by Meta-analysis.Methods PubMed, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), WanFang Data, and China Biology Medicine Database (CBM) were electronically searched for studies on risk factors for death in patients with Stenotrophomonas maltophilia infection. Two researchers independently completed literature screening, data extraction, and literature quality evaluation according to the criteria. RevMan 5.3 software was used for meta-analysis of the included literature.Results A total of 16 articles were included, with a sample size of 1449 cases and a total of 50 risk factors. Meta-analysis showed that acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ), indwelling central venous catheter, multiple organ dysfunction syndrome (MODS), sequential organ failure score (SOFA)>6, indwelling nasogastric tube, Charlson comorbidity index (CCI), mechanical ventilation, neutropenia, parenteral nutrition, indwelling catheter, surgery, use of carbapenem antibiotics, diabetes, use of glycopeptide antibiotics, septic shock, thrombocytopenia, hematological malignancies, and ICU were independent risk factors for death risk factors in patients with Stenotrophomonas maltophilia infection.Conclusion There are many risk factors for death in patients with Stenotrophomonas maltophilia infection, but the number of literatures on some influencing factors is small, and it is impossible to clarify its correlation with death after SMA infection. Large sample and high-quality prospective studies are needed to further clarify the risk factors for death in patients with S.maltophilia infection.

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更新日期/Last Update: 1900-01-01