[1]徐 昕.多糖降血糖作用及其机制研究进展[J].医学信息,2023,36(02):180-183.[doi:10.3969/j.issn.1006-1959.2023.02.040]
 XU Xin.Research Progress on Hypoglycemic Effect and Mechanism of Polysaccharides[J].Journal of Medical Information,2023,36(02):180-183.[doi:10.3969/j.issn.1006-1959.2023.02.040]
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多糖降血糖作用及其机制研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年02期
页码:
180-183
栏目:
综述
出版日期:
2023-01-15

文章信息/Info

Title:
Research Progress on Hypoglycemic Effect and Mechanism of Polysaccharides
文章编号:
1006-1959(2023)02-0180-04
作者:
徐 昕
(天津市河东区中医院内科,天津 300160)
Author(s):
XU Xin
(Department of Internal Medicine,Hedong District Traditional Chinese Medicine Hospital,Tianjin 300160,China)
关键词:
多糖口服降糖药糖尿病
Keywords:
PolysaccharideOral hypoglycemic drugsDiabetes mellitus
分类号:
TQ281;R587.1
DOI:
10.3969/j.issn.1006-1959.2023.02.040
文献标志码:
A
摘要:
随着糖尿病及其相关并发症发生率的不断上升,常规口服降糖药只能暂时性的控制血糖水平处于正常范围内。随着治疗疗程的不断延长,机体多个系统会受到一定损伤,部分患者会出现严重不良反应,且糖尿病并发症治疗无显著作用。因此,寻找有效降血糖、低毒、小副作用的天然物质备受关注,并且以及成为近年研究的新方向。研究发现,多糖具有降低血糖的功效,是一类活性多样的天然药物,其安全、低毒的优势是目前关于的热点。本文以下对多糖降血糖作用、机制以研究进展进行综述,并对应用多糖治疗糖尿病及糖尿病并发症的前景进行了展望,以期为多糖降糖药物的研发提供一定的参考依据。
Abstract:
With the increasing incidence of diabetes mellitus and its related complications, conventional oral hypoglycemic agents can only temporarily control blood glucose levels within the normal range. With the continuous extension of the course of treatment, multiple systems of the body will be damaged, some patients will have serious adverse reactions, and the treatment of diabetic mellitus complications has no significant effect. Therefore, the search for natural substances with effective hypoglycemic, low toxicity and small side effects has attracted much attention and has become a new direction of research in recent years. Studies have found that polysaccharides have the effect of lowering blood sugar. They are a kind of natural medicine with various activities. Their advantages of safety and low toxicity are currently hot spots. In this paper, the hypoglycemic effect and mechanism of polysaccharides are reviewed, and the prospect of the application of polysaccharides in the treatment of diabetes mellitus and diabetic mellitus complications is prospected, in order to provide some reference for the research and development of polysaccharide hypoglycemic drugs.

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更新日期/Last Update: 1900-01-01