[1]方良华.外用重组牛碱性成纤维细胞生长因子凝胶治疗颌面部软组织擦伤的临床疗效[J].医学信息,2023,36(10):165-167,171.[doi:10.3969/j.issn.1006-1959.2023.10.037]
　FANG Liang-hua.Clinical Efficacy of Recombinant Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Maxillofacial Soft Tissue Abrasion[J].Journal of Medical Information,2023,36(10):165-167,171.[doi:10.3969/j.issn.1006-1959.2023.10.037]
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外用重组牛碱性成纤维细胞生长因子凝胶治疗颌面部软组织擦伤的临床疗效()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年10期
页码:
165-167,171
栏目:
论著
出版日期:
2023-05-15

文章信息/Info

Title:
Clinical Efficacy of Recombinant Bovine Basic Fibroblast Growth Factor Gel in the Treatment of Maxillofacial Soft Tissue Abrasion
文章编号:
1006-1959（2023）10-0165-04
作者:
方良华
（铅山县人民医院口腔科，江西 铅山 334500）
Author(s):
FANG Liang-hua
(Department of Stomatology,Yanshan County People’s Hospital,Yanshan 334500,Jiangxi,China)
关键词:
重组牛碱性成纤维细胞生长因子; 颌面部软组织擦伤; 创面愈合; 瘢痕
Keywords:
Recombinant bovine basic fibroblast growth factor; Maxillofacial soft tissue abrasion; Wound healing; Scar
分类号:
R782.2
DOI:
10.3969/j.issn.1006-1959.2023.10.037
文献标志码:
A
摘要:
目的 研究外用重组牛碱性成纤维细胞生长因子（rb-bFGF）凝胶治疗颌面部软组织擦伤的临床疗效。方法 以2020年1月-2022年1月铅山县人民医院收治的60例颌面部软组织擦伤患者为研究对象，按照随机数字表法分为对照组与观察组，各30例。两组均给予清创处理，对照组采用红霉素软膏治疗，观察组外用rb-bFGF凝胶治疗。比较两组创面愈合时间、创面愈合率、创面疼痛程度[视觉模拟评分（VAS）]、二次创伤评分、并发症、温哥华瘢痕量表（VSS）评分及患者满意度。结果 观察组创面愈合时间短于对照组，且治疗第10天创面愈合率高于对照组（P＜0.05）；观察组治疗后创面VAS评分低于对照组（P＜0.05）；观察组二次创伤评分低于对照组（P＜0.05）；观察组并发症发生率低于对照组（P＜0.05）；观察组VSS评分低于对照组（P＜0.05）；观察组患者满意度高于对照组（P＜0.05）。结论 外用rb-bFGF凝胶治疗颌面部软组织擦伤效果确切，可加快创面愈合，减轻二次创伤，缓解创面疼痛，减少并发症及瘢痕增生，提高患者满意度。
Abstract:
Objective To study the clinical efficacy of recombinant bovine basic fibroblast growth factor (rb-bFGF) gel in the treatment of maxillofacial soft tissue abrasion.Methods A total of 60 patients with maxillofacial soft tissue abrasion admitted to Yanshan County People’s Hospital from January 2020 to January 2022 were divided into control group and observation group according to random number table method, with 30 cases in each group. Both groups were treated with debridement, while the control group was treated with erythromycin ointment, and the observation group was treated with rb-bFGF gel. The wound healing time, wound healing rate, wound pain degree [Visual Analogue Scale (VAS)], secondary trauma score, complications, Vancouver Scar Scale (VSS) score and patient satisfaction were compared between the two groups.Results The wound healing time of the observation group was shorter than that of the control group, and the wound healing rate on the 10th day of treatment was higher than that of the control group (P<0.05). The VAS score of the wound in the observation group was lower than that in the control group (P<0.05). The secondary trauma score of the observation group was lower than that of the control group (P<0.05). The incidence of complications in the observation group was lower than that in the control group (P<0.05). The VSS score of the observation group was lower than that of the control group(P<0.05). The satisfaction of patients in the observation group was higher than that in the control group (P<0.05).Conclusion External application of rb-bFGF gel in the treatment of maxillofacial soft tissue abrasions is effective, which can accelerate wound healing, reduce secondary trauma, relieve wound pain, reduce complications and scarring, and improve patient satisfaction.

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更新日期/Last Update: 1900-01-01