[1]赖 蓁,杨 洁,李赛银.阴道三维超声对体外受精-胚胎移植患者子宫内膜容受性及妊娠结局的预测价值[J].医学信息,2023,36(21):146-149.[doi:10.3969/j.issn.1006-1959.2023.21.034]
 LAI Zhen,YANG Jie,LI Sai-yin.Value of Three-dimensional Transvaginal Sonography in Predicting Endometrial Receptivity and Pregnancy Outcome in Patients Undergoing In Vitro Fertilization-embryo Transfer[J].Journal of Medical Information,2023,36(21):146-149.[doi:10.3969/j.issn.1006-1959.2023.21.034]
点击复制

阴道三维超声对体外受精-胚胎移植患者子宫内膜容受性及妊娠结局的预测价值()
分享到:

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
36卷
期数:
2023年21期
页码:
146-149
栏目:
诊疗技术
出版日期:
2023-11-01

文章信息/Info

Title:
Value of Three-dimensional Transvaginal Sonography in Predicting Endometrial Receptivity and Pregnancy Outcome in Patients Undergoing In Vitro Fertilization-embryo Transfer
文章编号:
1006-1959(2023)21-0146-04
作者:
赖 蓁杨 洁李赛银
(赣州市人民医院超声医学科1,党委办公室2,江西 赣州 341000)
Author(s):
LAI ZhenYANG JieLI Sai-yin
(Department of Ultrasound1,Office of a Party Committee2,Ganzhou People’s Hospital,Ganzhou 341000,Jiangxi,China)
关键词:
体外受精-胚胎移植阴道三维超声子宫内膜容受性妊娠结局
Keywords:
In vitro fertilization embryo transferThree-dimensional transvaginal sonographyEndometrial receptivityPregnancy outcome
分类号:
R445.1
DOI:
10.3969/j.issn.1006-1959.2023.21.034
文献标志码:
A
摘要:
目的 探究阴道三维超声(3D-TVS)对体外受精-胚胎移植(IVF-ET)患者子宫内膜容受性(ER)及妊娠结局的预测价值。方法 选择2021年4月-2022年6月于赣州市人民医院行IVF-ET治疗的100例女性为研究对象,依据其妊娠结局分为妊娠组61例与非妊娠组39例。采用3D-TVS检测其子宫内膜容受性,比较两组子宫内膜形态参数(子宫内膜厚度、子宫内膜容积、子宫内膜类型)与子宫内膜血流参数[血流指数(FI)、血管化指数(VI)、血管-血流指数(VFI)、血流阻力指数(RI)、搏动指数(PI)],采用多因素Logistic回归分析IVF-ET患者妊娠结局的独立影响因素,ROC曲线分析3D-TVS参数对IVF-ET患者妊娠结局的预测价值。结果 妊娠组与非妊娠组的子宫内膜形态参数(子宫内膜厚度、子宫内膜容积、子宫内膜类型)比较,差异无统计学意义(P>0.05),但两组子宫内膜血流参数(FI、VI、VFI、RI、PI)比较,差异有统计学意义(P<0.05);多因素Logistic分析显示,FI、VI、VFI、RI、PI是IVF-ET患者妊娠结局的独立影响因素(P<0.05);ROC曲线分析显示,3D-TVS参数预测IVF-ET患者妊娠结局的AUC值由高至低依次为VFI>FI>PI>RI>VI(P<0.05)。结论 3D-TVS可完整评估IVF-ET患者的子宫内膜容受性,其子宫内膜血流参数对IVF-ET妊娠结局具有良好的预测价值。
Abstract:
Objective To investigate the predictive value of three-dimensional transvaginal sonography (3D-TVS) on endometrial receptivity (ER) and pregnancy outcome in patients with in vitro fertilization embryo transfer (IVF-ET).Methods A total of 100 women who underwent IVF-ET treatment in Ganzhou People’s Hospital from April 2021 to June 2022 were selected as the research objects. According to their pregnancy outcomes, they were divided into pregnancy group (61 women) and non-pregnancy group (39 women). Endometrial receptivity was detected by 3D-TVS. The endometrial morphological parameters (endometrial thickness, endometrial volume, endometrial type) and endometrial blood flow parameters [blood flow index (FI), vascularization index (VI), vascular-blood flow index (VFI), blood flow resistance index (RI), pulsatility index (PI)] were compared between the two groups. Multivariate logistic regression was used to analyze the independent influencing factors of pregnancy outcome in IVF-ET patients. ROC curve was used to analyze the predictive value of 3D-TVS parameters on pregnancy outcome in IVF-ET patients.Results There was no significant difference in endometrial morphological parameters (endometrial thickness, endometrial volume, endometrial type) between the pregnancy group and the non-pregnancy group (P>0.05), but there was significant difference in endometrial blood flow parameters (FI, VI, VFI, RI, PI) between the two groups (P<0.05). Multivariate Logistic analysis showed that FI, VI, VFI, RI and PI were independent influencing factors of pregnancy outcome in IVF-ET patients (P<0.05). ROC curve analysis showed that the AUC value of 3D-TVS parameters in predicting pregnancy outcome of IVF-ET patients was VFI>FI>PI>RI>VI (P<0.05).Conclusion 3D-TVS can completely evaluate the endometrial receptivity of IVF-ET patients, and its endometrial blood flow parameters have good predictive value for IVF-ET pregnancy outcome.

参考文献/References:

[1]江帆,洪婧贞,高瑞卿,等.新鲜胚胎移植周期子宫内膜容受性超声指标与妊娠结局关系分析[J].生殖医学杂志,2022,31(10):1361-1365.[2]Doyle N,Jahandideh S,Hill MJ,et al.Effect of Timing by Endometrial Receptivity Testing vs Standard Timing of Frozen Embryo Transfer on Live Birth in Patients Undergoing In Vitro Fertilization: A Randomized Clinical Trial[J].JAMA,2022,328(21):2117-2125.[3]王彬,彭宇洪,梁见弟,等.子宫内膜容受性与体外受精/卵胞浆内单精子注射-胚胎移植患者妊娠结局的关系[J].中国优生与遗传杂志,2020,28(12):1532-1534,1541.[4]蒋振林,朱泽静,唐丽.超声监测子宫内膜对IVF-ET妊娠结局的预测价值[J].中国计划生育学杂志,2021,29(10):2126-2128,2249.[5]周秀萍,赵雅萍,王启亮,等.经阴道三维能量多普勒血流显像超声监测IVF-ET中子宫内膜参数评估子宫内膜容受性[J].浙江医学,2019,41(10):1053-1056.[6]寻志杰,高翔,韩静.经阴道彩超对不孕症患者子宫内膜容受性、血流动力学的评估及对IVF-ET妊娠结局的预测价值[J].中国妇幼健康研究,2022,33(2):50-55.[7]Kasahara Y,Hashimoto T,Yokomizo R,et al. Evaluation of Pregnancy Outcomes of Vitrified-Warmed Blastocyst Transfer before and after Endometrial Receptivity Analysis in Identical Patients with Recurrent Implantation Failure[J].Fertility & Reproduction,2021,3(2):35-41.[8]王会敏,肖祎炜,欧阳春艳,等.超声造影评价不孕症患者子宫内膜容受性的应用研究[J].中国超声医学杂志,2020,36(3):252-254.[9]李芷舒,鲁海鸥,张宇明,等.不孕患者移植当日子宫内膜容受性评估对临床妊娠率影响研究[J].中国实用妇科与产科杂志,2020,36(3):264-266.[10]邹旭彤,王琳,刘洋,等.经阴道超声检测激素替代周期子宫内膜血流参数对胚胎移植妊娠结局的评估价值[J].中国临床医学,2020,27(1):79-82.[11]王英华,鲁海鸥,李芷舒,等.胚胎移植日经阴道三维超声评估子宫内膜容受性对体外受精/卵泡质内单精子显微注射-胚胎移植患者妊娠结局预测价值研究[J].临床军医杂志,2020,48(2):191-192.[12]龙凤,张海英,何群燕,等.经阴道超声在体外受精—胚胎移植及冻融胚胎移植后早期妊娠中的规范化应用[J].中国妇幼保健,2020,35(4):695-699.[13]马丽,马燕.经阴道超声在体外受精-胚胎移植术后宫内外复合妊娠诊断中的应用[J].广西医学,2019,41(14):1832-1835.[14]李建荣,杨坤,邵蕾,等.经阴道超声子宫内膜变化系数预测体外受精-胚胎移植临床结局[J].中国超声医学杂志,2019,35(7):633-635.[15]于姣姣,陈玲,胡兵,等.经阴道三维超声评价子宫内膜容受性对体外受精-胚胎移植患者妊娠结局的预测价值[J].山东医药,2017,57(26):60-62.[16]陈淑霞,鄢曹鑫.不同超声参数在评估IVF-ET患者子宫内膜容受性中的价值[J].中华全科医学,2019,17(5):821-824.[17]张志峰,赵双丹,曹明雅,等.超声影像学评价对促排卵后妊娠结局的预测作用[J].河北医科大学学报,2019,40(3):324-328.[18]毛书霞,李宏波,吴意赟,等.三维超声定量指标对体外受精-胚胎移植中发生卵巢过度刺激综合征的预测价值[J].中国计划生育和妇产科,2019,11(2):41-44,97.[19]罗田田,肖春梅,郝丽娟.超声检查早期诊断体外受精-胚胎移植术后复合妊娠[J].中国介入影像与治疗学,2018,15(10):618-621.[20]刘耘利,许伟标,刘琼珠,等.经阴道三维超声对体外受精-胚胎移植患者子宫内膜容受性的评估及对妊娠结局的预测价值[J].中国临床医学影像杂志,2021,32(6):426-431.[21]邹淑伟,韩彦峰,吴秀英.彩色多普勒超声及内膜微血管密度在反复自然流产患者子宫内膜容受性评价中的应用[J].中国医药导报,2018,15(14):54-57.[22]高洁,余文惠,陈丹丹,等.三维超声在体外受精-胚胎移植成功后早孕期胎囊滞留宫角的诊断及指导预后的应用价值[J].中国妇产科临床杂志,2022,23(1):89-90.

相似文献/References:

[1]王红红.纵隔子宫IVF/ICSI-ET助孕前行宫腔镜下子宫纵隔切除手术对妊娠结局的影响[J].医学信息,2018,31(19):102.[doi:10.3969/j.issn.1006-1959.2018.19.030]
 WANG Hong-hong.Effect of Hysteroscopic Uterine Mediastinal Resection on Pregnancy Outcome before IVF/ICSI-ET in Uterus Septus[J].Journal of Medical Information,2018,31(21):102.[doi:10.3969/j.issn.1006-1959.2018.19.030]
[2]熊永崂,孙晓燕,聂晓莉,等.卵泡期半量长方案在反复种植失败患者再次行IVF-ET治疗中的疗效[J].医学信息,2022,35(14):116.[doi:10.3969/j.issn.1006-1959.2022.14.028]
 XIONG Yong-lao,SUN Xiao-yan,NIE Xiao-li,et al.Efficacy of Follicular Half-dose Long Protocol in Repeated IVF-ET for Patients with Failed Implantation[J].Journal of Medical Information,2022,35(21):116.[doi:10.3969/j.issn.1006-1959.2022.14.028]
[3]陈海霞,白晓红.ICSI在体外助孕Half-ICSI治疗中的有效性和安全性评估[J].医学信息,2020,33(05):74.[doi:10.3969/j.issn.1006-1959.2020.05.022]
 Chen Haixia,BaiXiaohong.Evaluation of ICSI effectiveness in Half-ICSI cycles[J].Journal of Medical Information,2020,33(21):74.[doi:10.3969/j.issn.1006-1959.2020.05.022]

更新日期/Last Update: 1900-01-01