[1]欧裕福,肖增明.腰椎融合术后邻近节段退变的发生因素及机制研究进展[J].医学信息,2024,37(10):165-169.[doi:10.3969/j.issn.1006-1959.2024.10.036]
 OU Yu-fu,XIAO Zeng-ming.Research Progress on Factors and Mechanism of Adjacent Segment Degeneration After Lumbar Fusion[J].Journal of Medical Information,2024,37(10):165-169.[doi:10.3969/j.issn.1006-1959.2024.10.036]
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腰椎融合术后邻近节段退变的发生因素及机制研究进展()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
37卷
期数:
2024年10期
页码:
165-169
栏目:
综述
出版日期:
2024-05-15

文章信息/Info

Title:
Research Progress on Factors and Mechanism of Adjacent Segment Degeneration After Lumbar Fusion
文章编号:
1006-1959(2024)10-0165-05
作者:
欧裕福肖增明
(1.中山大学附属第一医院广西医院骨科,广西 南宁 530022;2.广西医科大学研究生学院,广西 南宁 530021)
Author(s):
OU Yu-fuXIAO Zeng-ming
(1.Department of Orthopaedics,Guangxi Hospital,the First Affiliated Hospital of Sun Yat-sen University,Nanning 530022,Guangxi,China;2.Graduate School of Guangxi Medical University,Nanning 530021,Guangxi,China)
关键词:
腰椎融合邻近节段退变生物力学
Keywords:
Lumbar fusionAdjacent segment degenerationBiomechanics
分类号:
R687.3
DOI:
10.3969/j.issn.1006-1959.2024.10.036
文献标志码:
A
摘要:
腰椎退变性疾病常引起慢性腰痛,腰椎减压及融合手术是治疗腰椎退变性疾病的主要有效方法,取得了显著的临床效果,但长期随访发现腰椎融合术后邻近节段病变发生率并不低,是导致二次手术的主要因素。腰椎融合术后邻近节段退变发生机制涉及生物力学、生理病理学、分子生物学等诸多学科和因素,是一个复杂的生理病理发展过程。本文就腰椎融合术后邻近节段病变的发生因素及机制进行综述,以期为临床外科制定手术方案提供理论参考,并为干预邻近节段病变提供理论依据。
Abstract:
Degenerative diseases of the lumbar spine often cause chronic low back pain. Lumbar decompression and fusion surgery is the main and effective method for the treatment of degenerative diseases of the lumbar spine, and has achieved remarkable clinical results. However, long-term follow-up found that the incidence of adjacent segment lesions after lumbar fusion was not low, which was the main factor leading to secondary surgery. The mechanism of adjacent segment degeneration after lumbar fusion involves many disciplines and factors such as biomechanics, physiopathology, molecular biology, etc. It is a complex physiological and pathological development process. This article reviews the factors and mechanisms of adjacent segment lesions after lumbar fusion, in order to provide a theoretical reference for clinical surgery to formulate surgical plans and provide a theoretical basis for the intervention of adjacent segment lesions.

参考文献/References:

[1]Lu K,Liliang PC,Wang HK,et al.Reduction in adjacent-segment degeneration after multilevel posterior lumbar interbody fusion with proximal DIAM implantation[J].J Neurosurg Spine,2015,23(2):190-196.[2]Tsuji T,Watanabe K,Hosogane N,et al.Risk factors of radiological adjacent disc degeneration with lumbar interbody fusion for degenerative spondylolisthesis[J].J Orthop Sci,2016,21(2):133-137.[3]Ha KY,Kim YH,Ahn JH.Is it real adjacent segment pathology by stress concentration after limited fusion in degenerative lumbar scoliosis?[J].Spine (Phila Pa 1976),2014,39(13):1059-1066.[4]Kim JY,Ryu DS,Paik HK,et al.Paraspinal muscle, facet joint, and disc problems: risk factors for adjacent segment degeneration after lumbar fusion[J].Spine J,2016,16(7):867-875.[5]Sakaura H,Miwa T,Yamashita T,et al.Posterior lumbar interbody fusion with cortical bone trajectory screw fixation versus posterior lumbar interbody fusion using traditional pedicle screw fixation for degenerative lumbar spondylolisthesis: a comparative study[J].J Neurosurg Spine,2016,25(5):591-595.[6]Wang H,Ma L,Yang D,et al.Incidence and risk factors of adjacent segment disease following posterior decompression and instrumented fusion for degenerative lumbar disorders[J].Medicine (Baltimore),2017,96(5):e6032.[7]Tobert DG,Antoci V,Patel SP,et al.Adjacent Segment Disease in the Cervical and Lumbar Spine[J].Clin Spine Surg,2017,30(3):94-101.[8]Okuda S,Yamashita T,Matsumoto T,et al.Adjacent Segment Disease After Posterior Lumbar Interbody Fusion: A Case Series of 1000 Patients[J].Global Spine J,2018,8(7):722-727.[9]Scemama C,Magrino B,Gillet P,et al.Risk of adjacent-segment disease requiring surgery after short lumbar fusion: results of the French Spine Surgery Society Series[J].J Neurosurg Spine,2016,25(1):46-51.[10]Hashimoto K,Aizawa T,Kanno H,et al.Adjacent segment degeneration after fusion spinal surgery-a systematic review[J].Int Orthop,2019,43(4):987-993.[11]Dantas FL,Dantas F,Caires AC,et al.Adjacent segment degeneration after posterolateral lumbar fusion: results and complications of posterior revision surgery[J].J Neurosurg Sci,2023,67(4):446-453.[12]陶勇.保留后方韧带复合体对腰椎后路手术影响的生物力学分析及临床疗效观察[D].南宁:广西医科大学,2016.[13]Wu CC,Jin HM,Yan YZ,et al.Biomechanical Role of the Thoracolumbar Ligaments of the Posterior Ligamentous Complex: A Finite Element Study[J].World Neurosurg,2018,112:e125-e133.[14]Tuli SM,Kapoor V,Jain AK,et al.Spinaplasty following lumbar laminectomy for multilevel lumbar spinal stenosis to prevent iatrogenic instability[J].Indian J Orthop,2011,45(5):396-403. [15]Mu X,Ou Y,Jiancuo A,et al.Clinical outcomes of transarticular and lateral vertebral canal lumbar interbody fusion for lumbar spinal stenosis: a retrospective study of 124 cases[J].Int J Clin Exp Med,2018,11(11):12429-12436[16]刘玉增,海涌,杨晋才,等.不同融合节段后路减压椎间融合内固定术对邻近节段稳定性影响的影像学分析[J].中国骨与关节杂志,2013,2(10):563-567.[17]Phan K,Xu J,Maharaj MM,et al.Outcomes of Short Fusion versus Long Fusion for Adult Degenerative Scoliosis: A Systematic Review and Meta-analysis[J].Orthop Surg,2017,9(4):342-349.[18]何守玉,朱锋,邱勇,等.长、短节段融合内固定治疗成人退变性脊柱侧凸并发症分析[J].中国骨与关节杂志,2015,4(3):176-181.[19]赵宇,杨开舜,李绍波.腰椎融合节段数与术后相邻节段退变及远期疗效的关系[J].西南国防医药,2013,23(4):388-391.[20]Mu X,Li Z,Yin D,et al.Biomechanical Effects of Fixation of Different Segments of Goat Lumbar Spine on Adjacent Segmental Motion and Intradiscal Pressure Change[J].Med Sci Monit,2019,25:4885-4891.[21]Li C,He Q,Tang Y,et al.The fate of adjacent segments with pre-existing degeneration after lumbar posterolateral fusion: the influence of degenerative grading[J].Eur Spine J,2015,24(11):2468-2473.[22]刘啸,杨晓松,于淼,等.腰椎融合术后相邻节段旋转角度、椎间活动度及椎间隙高度变化的临床分析[J].中国脊柱脊髓杂志,2019,29(2):109-115.[23]王辉.脊柱融合术后邻近节段退变的危险因素分析[D].石家庄:河北医科大学,2019.[24]Ye J,Yang S,Wei Z,et al.Incidence and Risk Factors for Adjacent Segment Disease After Transforaminal Lumbar Interbody Fusion in Patients with Lumbar Degenerative Diseases[J].Int J Gen Med,2021,14:8185-8192.[25]Tian H,Wu A,Guo M,et al.Adequate Restoration of Disc Height and Segmental Lordosis by Lumbar Interbody Fusion Decreases Adjacent Segment Degeneration[J].World Neurosurg,2018,118:e856-e864.[26]Soh J,Lee JC,Shin BJ.Analysis of risk factors for adjacent segment degeneration occurring more than 5 years after fusion with pedicle screw fixation for degenerative lumbar spine[J].Asian Spine J,2013,7(4):273-281.[27]Cao Y,Liu F,Wan S,et al.Biomechanical evaluation of different surgical procedures in single-level transforaminal lumbar interbody fusion in vitro[J].Clin Biomech (Bristol, Avon),2017,49:91-95.[28]Heo Y,Park JH,Seong HY,et al.Symptomatic adjacent segment degeneration at the L3-4 level after fusion surgery at the L4-5 level: evaluation of the risk factors and 10-year incidence[J].Eur Spine J,2015,24(11):2474-2480.[29]张生,祁学强,常建琪.腰椎不同融合方式对邻近节段影响的三维有限元分析[J].延安大学学报(医学科学版),2017,15(4):39-42,97.[30]Wangsawatwong P,Sawa AGU,de Andrada Pereira B,et al.Adjacent-segment effects of lumbar cortical screw-rod fixation versus pedicle screw-rod fixation with and without interbody support[J].J Neurosurg Spine,2021,35(3):263-269.[31]Kumaran Y,Shah A,Katragadda A,et al.Iatrogenic muscle damage in transforaminal lumbar interbody fusion and adjacent segment degeneration: a comparative finite element analysis of open and minimally invasive surgeries[J].Eur Spine J,2021,30(9):2622-2630.[32]Benneker LM,Heini PF,Alini M,et al.2004 Young Investigator Award Winner: vertebral endplate marrow contact channel occlusions and intervertebral disc degeneration[J].Spine (Phila Pa 1976),2005,30(2):167-173.[33]Shi J,Pang L,Jiao S.The response of nucleus pulposus cell senescence to static and dynamic compressions in a disc organ culture[J].Biosci Rep,2018,38(2):BSR20180064.[34]Li P,Hou G,Zhang R,et al.High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway[J].Arthritis Res Ther,2017,19(1):209.[35]Bartolini D,Dallaglio K,Torquato P,et al.Nrf2-p62 autophagy pathway and its response to oxidative stress in hepatocellular carcinoma[J].Transl Res,2018,193:54-71.[36]Jiang W,Zhang X,Hao J,et al.SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells[J].Sci Rep,2014,4:7456.

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更新日期/Last Update: 1900-01-01