[1]许志瑶,朱国云.静滴甲泼尼龙琥珀酸钠联合布地奈德及特布他林雾化治疗支气管肺炎的疗效[J].医学信息,2026,39(01):131-134.[doi:10.3969/j.issn.1006-1959.2026.01.024]
　XU Zhiyao,ZHU Guoyun.Efficacy of Intravenous Methylprednisolone Sodium Succinate Combined with Atomizationof Budesonide and Terbutaline in the Treatment of Bronchopneumonia[J].Journal of Medical Information,2026,39(01):131-134.[doi:10.3969/j.issn.1006-1959.2026.01.024]
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静滴甲泼尼龙琥珀酸钠联合布地奈德及特布他林雾化治疗支气管肺炎的疗效()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
39卷
期数:
2026年01期
页码:
131-134
栏目:
临床证据信息
出版日期:
2026-01-01

文章信息/Info

Title:
Efficacy of Intravenous Methylprednisolone Sodium Succinate Combined with Atomizationof Budesonide and Terbutaline in the Treatment of Bronchopneumonia
文章编号:
1006-1959（2026）01-0131-04
作者:
许志瑶; 朱国云
新干县人民医院儿科，江西 新干 331300
Author(s):
XU Zhiyao;  ZHU Guoyun
Department of Pediatrics, Xingan County People′s Hospital, Xingan 331300, Jiangxi, China
关键词:
支气管肺炎; 甲泼尼龙琥珀酸钠; 布地奈德; 特布他林
Keywords:
Bronchopneumonia;  Methylprednisolone sodium succinate;  Budesonide;  Terbutaline
分类号:
R563
DOI:
10.3969/j.issn.1006-1959.2026.01.024
文献标志码:
A
摘要:
目的 探究静滴甲泼尼龙琥珀酸钠（MPSS）联合布地奈德（BD）及特布他林（TB）雾化治疗支气管肺炎的临床疗效。方法 选取2021年1月-2024年7月新干县人民医院儿科收治的60例支气管肺炎患者，根据随机数字表法分为A组（30例）与B组（30例），A组采用BD+TB雾化治疗，B组应用MPSS静滴联合BD+TB雾化治疗，比较两组临床疗效、症状改善情况、症状消退时间（发热、咳嗽、气促、肺部啰音）、生化指标[白细胞计数（WBC）、C反应蛋白（CRP）、降钙素原（PCT）]、不良反应。结果 B组总有效率（96.67%）高于A组（83.33%）（P＜0.05）；治疗3 d后，两组症状评分（发热、咳嗽、气促、肺部啰音）低于治疗前，且B组症状评分（发热、咳嗽、气促、肺部啰音）低于A组（P＜0.05）；B组发热、咳嗽、气促、肺部啰音症状消退时间均短于A组（P＜0.05）；两组治疗后生化指标（WBC、CRP、PCT）低于治疗前，且B组生化指标（WBC、CRP、PCT）低于A组（P＜0.05）；两组不良反应发生率比较，差异无统计学意义（P＞0.05）。结论 MPSS静滴联合BD+TB雾化治疗支气管肺炎的疗效肯定，可改善患者临床症状，加速症状消退，对患者生化指标具有积极改善作用，且不增加患者不良反应发生率。
Abstract:
Objective To investigate the clinical efficacy of intravenous methylprednisolone sodium succinate (MPSS) combined with atomization of budesonide (BD) and terbutaline (TB) in the treatment of bronchopneumonia. Methods Sixty patients with bronchopneumonia admitted to the Department of Pediatrics, Xingan County People′s Hospital from January 2021 to July 2024 were selected and divided into group A (30 patients) and group B (30 patients) according to the random number table method. Group A was treated with atomization of BD+TB, and group B was treated with MPSS intravenous drip combined with atomization of BD+TB. The clinical efficacy, symptom improvement, symptom regression time (fever, cough, shortness of breath, pulmonary rales), biochemical indexes[white blood cell count (WBC), C-reactive protein (CRP), procalcitonin (PCT)] and adverse reactions were compared between the two groups. Results The total effective rate of group B (96.67%) was higher than that of group A (83.33%) (P<0.05). After 3 days of treatment, the symptom scores (fever, cough, shortness of breath, pulmonary rales) of the two groups were lower than those before treatment, and the symptom scores (fever, cough, shortness of breath, pulmonary rales) of group B were lower than those of group A (P<0.05). The disappearance time of fever, cough, shortness of breath and pulmonary rales in group B was shorter than that in group A (P<0.05). The biochemical indexes (WBC, CRP, PCT) of the two groups after treatment were lower than those before treatment, and the biochemical indexes (WBC, CRP, PCT) of group B were lower than those of group A (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion MPSS intravenous drip combined with atomization of BD+TB is effective in the treatment of bronchopneumonia, which can improve their clinical symptoms, accelerate the regression of symptoms, improve the biochemical indexes, and do not increase the incidence of adverse reactions.

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更新日期/Last Update: 1900-01-01