[1]王 然,张 军.超敏肌钙蛋白Ⅰ检测在糖尿病心肌损伤早期诊断中的价值[J].医学信息,2019,32(19):174-175.[doi:10.3969/j.issn.1006-1959.2019.19.058]
　WANG Ran,ZHANG Jun.The Value of Detection of Hypersensitive Troponin I in Early Diagnosis of Diabetic Myocardial Injury[J].Journal of Medical Information,2019,32(19):174-175.[doi:10.3969/j.issn.1006-1959.2019.19.058]
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超敏肌钙蛋白Ⅰ检测在糖尿病心肌损伤早期诊断中的价值()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
32卷
期数:
2019年19期
页码:
174-175
栏目:
诊疗技术
出版日期:
2019-10-01

文章信息/Info

Title:
The Value of Detection of Hypersensitive Troponin I in Early Diagnosis of Diabetic Myocardial Injury
文章编号:
1006-1959（2019）19-0174-02
作者:
王 然;  张 军
（佳木斯市中心医院检验科，黑龙江 佳木斯 154002）
Author(s):
WANG Ran; ZHANG Jun
(Department of Clinical Laboratory,Jiamusi Central Hospital,Jiamusi 154002,Heilongjiang,China)
关键词:
超敏肌钙蛋白Ⅰ; 糖尿病; 心肌损伤; 早期诊断
Keywords:
Hypersensitive troponin I; Diabetes; Myocardial injury; Early diagnosis
分类号:
R446.1；R587.2
DOI:
10.3969/j.issn.1006-1959.2019.19.058
文献标志码:
A
摘要:
目的 探讨在糖尿病心肌损伤的早期诊断中检测血清超敏肌钙蛋白Ⅰ（hs-cTnⅠ）的价值。方法 选取2017年1月~2019年1月本院收治的103例2型糖尿病合并心肌损伤患者为观察组，选取同期行健康体检的100例志愿者为对照组，分别检测两组血清中天门冬氨酸氨基转移酶（AST）、肌酸激酶（CK）、肌酸激酶同工酶（CK-MB）、糖化血红蛋白（HbA1c）及hs-cTnⅠ水平并比较。结果 两组AST、CK、CK-MB水平比较，差异无统计学意义（P＞0.05）；观察组HbA1c及hs-cTnⅠ水平高于对照组，差异有统计学意义（P＜0.05）；在观察组患者中，HbA1c≤6.4%组与HbA1c＞6.4%组的患者AST、CK及CK-MB水平比较，差异无统计学意义（P＞0.05），而HbA1c≤6.4%组hs-cTnⅠ水平低于HbA1c＞6.4%组，差异有统计学意义（P＜0.05）。结论 针对糖尿病心肌损伤，通过对患者hs-cTnⅠ进行检测，有助于疾病的早期诊断及治疗。
Abstract:
Objective To investigate the value of serum hypersensitive troponin I (hs-cTnI) in the early diagnosis of diabetic myocardial injury. Methods 103 patients with type 2 diabetes mellitus complicated with myocardial injury admitted to our hospital from January 2017 to January 2019 were enrolled in the observation group. 100 volunteers who underwent healthy physical examination at the same time were selected as the control group. The levels of acid aminotransferase (AST), creatine kinase (CK) and creatine kinase isoenzyme (CK-MB), glycated hemoglobin (HbAlc) and hs-cTnI were measured and compared.Results There were no significant differences in the levels of AST, CK and CK-MB between the two groups (P>0.05). The levels of HbA1c and hs-cTnI in the observation group were higher than those in the control group,the difference was statistically significant (P<0.05). There were no significant differences in AST, CK and CK-MB between HbAlc≤6.4% and HbA1c>6.4% in the observation group (P>0.05). The hs-cTnI of HbA1c≤6.4% was lower than that of HbA1c>6.4%, the difference was statistically significant (P<0.05).Conclusion For the diagnosis of diabetic myocardial injury, the detection of hs-cTnI in patients is helpful for the early diagnosis and treatment of the disease.

参考文献/References:

[1]任慧鹏.cTnI、hs-CRP检测在轮状病毒肠炎致心肌损伤诊断中的价值[J].中国实用医药,2017,26(2):178. [2]汤勇才,任惠铭,黄小媛,等.超敏肌钙蛋白I对早期心肌梗死和脑血管意外的诊断价值[J].热带医学杂志,2018,33(6):47-50. [3]张成磊,黄勇翔,邸师红,等.高敏肌钙蛋白I、肌钙蛋白I联合心肌标志物对微小心肌损伤的早期诊断价值[J].检验医学与临床,2017,14(22):665-667. [4]Kondo T,Kobayashi D,Mochizuki M,et al.Analysis of the causes of discrepancies in troponin I concentrations as measured by ARCHITECT High-Sensitive Troponin I ST and STACIA CLEIA cTnI[J].Ann Clin Biochem,2017,54(1):121-126. [5]陈嘉雯,彭淑莹.超敏肌钙蛋白Ⅰ在急性心肌梗死早期诊断中的应用价值[J].国际医药卫生导报,2014(7):959-961.

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更新日期/Last Update: 2019-10-01