[1]张宇,杨楠.胃肠道间质瘤临床诊疗及预后因素的研究[J].医学信息,2020,33(08):58-60.[doi:10.3969/j.issn.1006-1959.2020.08.019]
　ZHANG Yu,YANG Nan.The Treatment and Prognostic of Gastrointestinal Stromal Tumors[J].Medical Information,2020,33(08):58-60.[doi:10.3969/j.issn.1006-1959.2020.08.019]
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胃肠道间质瘤临床诊疗及预后因素的研究()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
33卷
期数:
2020年08期
页码:
58-60
栏目:
综述
出版日期:
2020-04-15

文章信息/Info

Title:
The Treatment and Prognostic of Gastrointestinal Stromal Tumors
文章编号:
1006-1959（2020）08-0058-03
作者:
张宇; 杨楠
（赤峰市医院，内蒙古 赤峰 024000）
Author(s):
ZHANG Yu; YANG Nan
(Chifeng Municipal Hospital,Inner Mongolia,Chifeng 024000,China)
关键词:
胃肠道间质瘤; 生物学行为; 预后
Keywords:
Gastrointestinal stromal tumor; Biological behavior; Prognosis
分类号:
R735
DOI:
10.3969/j.issn.1006-1959.2020.08.019
文献标志码:
A
摘要:
胃肠道间质瘤（GIST）是常见的消化道间叶源性肿瘤，由未分化或多潜能分化的梭形或上皮样细胞构成，其发病隐匿，临床特征缺乏特异性。目前，GIST的诊断依赖于特定的组织学表现以及免疫组化结果，其对放化疗均不敏感，治疗仍以手术切除为主。近年来，GIST的临床诊治取得较大进展，但仍存在早期诊断不易、转移性GIST治疗困难、伊马替尼耐药后难以进一步治疗、生物学行为难以预测、预后难以判断等问题。本文就GIST诊断、治疗及预后作一综述，以期为临床治疗GIST提供参考。
Abstract:
Gastrointestinal stromal tumor (GIST) is a common alimentary tract mesenchymal tumor, which is composed of undifferentiated or multipotential fusiform or epithelioid cells, and the incidence hidden, the clinical manifestations are lack of specificity. The diagnosis of GIST depends on the specific histology and immunohistochemical results, it is not sensitive to radiotherapy and chemotherapy, and surgical resection is still the main treatment. In recent years, great achievements have been made in the study of GIST, but there are still some problems, such as the difficulty in early diagnosis of GIST, the difficulty in treatment of metastatic GIST, the difficulty in further treatment after imatinib resistance, the difficulty in predicting biological behavior, the difficulty in judging prognosis and the incomplete unity of the definition of benign and malignant. This article will review the current situation of diagnosis, treatment and prognosis of GIST in order to provide some guidance for clinical practice in the future.

参考文献/References:

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更新日期/Last Update: 2020-04-15