[1]李 强,尚翠侠,马 姣,等.安脑丸对脑卒中后焦虑抑郁患者的治疗作用[J].医学信息,2021,34(07):146-149.[doi:10.3969/j.issn.1006-1959.2021.07.041]
 LI Qiang,SHANG Cui-xia,MA Jiao,et al.Effect of Annao Pill on Treatment of Post-stroke Anxiety Depression[J].Medical Information,2021,34(07):146-149.[doi:10.3969/j.issn.1006-1959.2021.07.041]
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安脑丸对脑卒中后焦虑抑郁患者的治疗作用()

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年07期
页码:
146-149
栏目:
药物与临床
出版日期:
2021-04-01

文章信息/Info

Title:
Effect of Annao Pill on Treatment of Post-stroke Anxiety Depression
文章编号:
1006-1959(2021)07-0146-04
作者:
李 强尚翠侠马 姣
(西安交通大学第一附属医院精神心理科1,康复医学科2,陕西 西安 710061)
Author(s):
LI QiangSHANG Cui-xiaMA Jiaoet al.
(Department of Psychiatry1,Department of Rehabilitation Medicine2,the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061,Shaanxi,China)
关键词:
安脑丸脑卒中焦虑抑郁
Keywords:
AnnaopillStrokeAnxietyDepression
分类号:
R743
DOI:
10.3969/j.issn.1006-1959.2021.07.041
文献标志码:
A
摘要:
目的 观察安脑丸对脑卒中后焦虑抑郁患者的治疗作用。方法 选择2019年4月~12月西安交通大学第一附属医院及渭南市第三医院康复医学科门诊及住院收治的脑卒中后合并有焦虑抑郁患者71例,采用随机数字表法分为试验组(35例)和对照组(36例)。两组均予以神经系统药物治疗、康复治疗及心理治疗,在此基础上对照组口服黛力新治疗,观察组口服安脑丸治疗,于用药3周及6周后分别比较两组治疗后缓解焦虑及抑郁效果、神经功能情况、日常生活活动能力及不良反应发生情况。结果 治疗后3周,试验组缓解焦虑及抑郁总有效率高于对照组,差异有统计学意义(P<0.05);治疗后6周,试验组和对照组缓解焦虑、抑郁总有效率比较,差异无统计学意义(P>0.05)。试验组治疗后3周及6周日常生活活动能力情况优于对照组,差异有统计学意义(P<0.05)。两组治疗后3周及6周神经功能情况、不良反应发生率比较,差异无统计学意义(P>0.05)。结论 安脑丸治疗脑卒中后焦虑、抑郁安全有效,可修复受损神经,提高日常生活活动能力,且其系中药制剂,治疗后胃肠反应小,患者容易接受,依从性好。
Abstract:
Objective To observe the therapeutic effect of Annao Pill on patients with anxiety and depression after stroke.Methods From April to December 2019, 71 patients with anxiety and depression who were admitted to the outpatient and inpatient departments of the Rehabilitation Medicine Department of the First Affiliated Hospital of Xi’an Jiaotong University and Weinan Third Hospital were selected.Using random number table method, they were divided into experimental group (35 cases) and control group (36 cases).Both groups were treated with neurologic medication, rehabilitation and psychotherapy. On this basis, the control group was treated with Deanxit, and the observation group was treated with Annao pill. After 3 weeks and 6 weeks of treatment, the two groups were treated with remission after treatment. Anxiety and depression effects, neurological function, activities of daily living, and occurrence of adverse reactions.Results 3 after treatment, the total effective rate of relieving anxiety and depression in the experimental group was higher than that in the control group,the difference was statistically significant (P<0.05);6 weeks after treatment, there was no statistically significant difference between the experimental group and the control group in the total effective rate of relieving anxiety and depression (P>0.05).The activities of daily living in the experimental group were better than those in the control group at 3 and 6 weeks after treatment,the difference was statistically significant (P<0.05).There was no statistically significant difference in the neurological function and the incidence of adverse reactions between the two groups at 3 and 6 weeks after treatment (P>0.05).Conclusion Annao Pill is a safe and effective treatment for anxiety and depression after stroke. It can repair damaged nerves and improve activities of daily living. It is a traditional Chinese medicine preparation. After treatment, gastrointestinal reactions are small, patients are easy to accept, and have good compliance.

参考文献/References:

[1]陈敬敏.研究安脑丸治疗急性脑梗塞的有效性[J].中国妇幼健康研究,2016,27(S2):266. [2]岳丽萍,郭雅明,汪金涛.安脑丸联合阿立哌唑治疗精神分裂症的临床研究[J].现代药物与临床,2018,33(7):1648-1651. [3]吴荣,康亭亭,闫洁.不同时间点脑卒中后残疾患者情绪障碍发生率及其变化趋势[J].山西医药杂志,2020,49(4):393-394. [4]孙远征,孙姜云,韩数.中风后焦虑症研究现状[J].辽宁中医杂志,2014,41(7):41-46. [5]刘娟,庞敬涛,田立.首发缺血性卒中后抑郁中医证型与情绪表现特点相关性[J].中国中医基础医学杂志,2020,26(6):796-798. [6]费锦锋.乌灵胶囊联合黛力新治疗脑卒中后抑郁100例临床观察[J].新中医,2015,47(6):27-28. [7]崔嵬,王新波,徐世杰,等.安脑丸的药效学研究[J].中国中医药信息杂志,1999,5(8):26-27. [8]易全民,漆琼蔚,蒋荣峰.安脑丸联合奥氮平治疗脑梗死后焦虑抑郁患者临床疗效观察[J].实用医院临床杂志,2020,17(5):5-9. [9]罗洪民,陆品刚,彭跃文,等.电针联合安脑丸治疗急性脑梗死临床观察[J].中医药临床杂志,2015,6(4):104-105. [10]梁慧,文国强.安脑丸对脑出血大鼠学习记忆功能及血肿周围BDNF、NGB表达的影响[J].卒中与神经疾病,2014,21(6):327-329. [11]刘璐,黄庆嘉,陈炜,等.逐瘀安脑丸对脑出血小鼠TLR4介导的神经炎症反应的影响[J].四川中医,2019,37(3):41-44. [12]韩苗苗,唐学军,裴良艳,等.安脑丸对大鼠大脑皮质神经元氧糖剥夺损伤的防护作用[J].中国医药,2013,8(2):176-178. [13]赖天宝,宋艳玲,余光,等.电针结合安脑丸对脑梗死大鼠模型的神经保护作用[J].华中科技大学学报(医学版),2013,42(1):16-21. [14]魏爱宣,孙瑜,张晓军,等.安脑丸与艾司西酞普兰联合治疗脑卒中后抑郁患者的临床效果[J].中国药物经济学,2015,10(S2):104-105. [15]王国清,贾炜,程玲玲,等.艾司西酞普兰联合安脑丸治疗脑卒中后抑郁的疗效观察[C]//中国医院药学杂志学术年会.中国医院药学杂志编辑部,2016. [17]储新娟,涂志兰,侯双兴.安脑丸联合枸橼酸坦度螺酮治疗耳鸣患者的临床观察[J].中国医药导刊,2016,18(12):1254-1255. [18]徐永献.安脑丸治疗脑溢血疗效观察[J].现代诊断与治疗,2016,27(22):4230-4231. [19]汤光花,韩亚琼,李庆丽.安脑丸治疗癫痫的临床疗效及对海马5-HT含量及IL-1β、IL-6基因表达的影响[J].光明中医,2019,34(2):230-233. [20]简航宇,温灵武,杨世映.安脑丸对高血压合并失眠病人血压变异性和睡眠质量的影响[J].中西医结合心脑血管病杂志, 2019,17(21):3445-3447. [21]王志军.艾司西酞普兰联合安脑丸治疗脑卒中后抑郁的临床价值及可行性研究[J].医学信息,2015,28(9):25.

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更新日期/Last Update: 1900-01-01