[1]齐 芳,王海云.七氟烷吸入麻醉与异丙酚静脉麻醉对疝气手术患儿血流动力学、应激反应及麻醉效果的影响[J].医学信息,2021,34(17):120-122.[doi:10.3969/j.issn.1006-1959.2021.17.031]
　QI Fang,WANG Hai-yun.Effects of Sevoflurane Inhalation Anesthesia and Propofol Intravenous Anesthesia on Hemodynamics, Stress Response and Anesthesia Effects in Children with Hernia Surgery[J].Medical Information,2021,34(17):120-122.[doi:10.3969/j.issn.1006-1959.2021.17.031]
点击复制

七氟烷吸入麻醉与异丙酚静脉麻醉对疝气手术患儿血流动力学、应激反应及麻醉效果的影响()
分享到：

医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
34卷
期数:
2021年17期
页码:
120-122
栏目:
论著
出版日期:
2021-09-01

文章信息/Info

Title:
Effects of Sevoflurane Inhalation Anesthesia and Propofol Intravenous Anesthesia on Hemodynamics, Stress Response and Anesthesia Effects in Children with Hernia Surgery
文章编号:
1006-1959（2021）17-0120-03
作者:
齐 芳; 王海云
（1.天津医科大学三中心临床学院，天津 300170； 2.天津市重症疾病体外生命支持重点实验室/天津市人工细胞工程技术研究中心/ 天津市肝胆研究所，天津 300170； 3.天津市蓟州区人民医院麻醉科，天津 301900； 4.天津市第三中心医院麻醉科，天津 300170）
Author(s):
QI Fang; WANG Hai-yun
(1.The Third Center Clinical College of Tianjin Medical University,Tianjin 300170,China; 2.Tianjin Key Laboratory of In Vitro Life Support for Critical Diseases/Tianjin Artificial Cell Engineering Technology Research Center/Tianjin Hepatobiliary Research Institute,Tianjin 300170,China; 3.Department of Anesthesiology,People’s Hospital of Jizhou District,Tianjin 301900,China; 4.Department of Anesthesiology,Tianjin Third Central Hospital,Tianjin 300170,China)
关键词:
疝气; 儿童; 七氟烷吸入麻醉; 异丙酚静脉麻醉; 血流动力学; 应激反应
Keywords:
Hernia; Children; Sevoflurane inhalation anesthesia; Propofol intravenous anesthesia;  Hemodynamics; Stress response
分类号:
R614
DOI:
10.3969/j.issn.1006-1959.2021.17.031
文献标志码:
A
摘要:
目的 比较对拟行手术治疗的疝气患儿应用七氟烷吸入麻醉与异丙酚静脉麻醉的效果，评估其对患儿血流动力学、应激反应的影响。方法 选取2019年10月-2020年10月在我院接受手术治疗的疝气患儿78例，根据随机数字表法分为吸入组和静脉组，各39例。吸入组行七氟烷吸入麻醉，静脉组给予异丙酚静脉麻醉，比较麻醉期两组血流动力学[收缩压（SBP）、舒张压（DBP）及心率（HR）]、应激反应[肾素(R)、去甲肾上腺素（NE）及肾上腺素（E）]及术后意识恢复情况（意识恢复时间、定向力恢复时间、首次排气时间及清醒时间）。结果 T1、T2、T3时，两组NE、E、R、SBP、DBP及HR水平均较T0时上升，吸入组的上升幅度更小，差异有统计学意义（P＜0.05）；吸入组的意识恢复时间、定向力恢复时间、首次排气时间及清醒时间均比静脉组更短，差异有统计学意义（P＜0.05）；吸入组诱导期及苏醒期的PAED评分均比静脉组更低，差异有统计学意义（P＜0.05）。结论 对实施手术治疗的疝气患儿应用七氟烷吸入麻醉的效果比异丙酚静脉麻醉更为理想，且对患儿血流动力学影响较小，可减轻机体应激反应，缩短患儿意识恢复时间。
Abstract:
Objective To compare the effects of sevoflurane inhalation anesthesia and propofol intravenous anesthesia on children with hernia who are to be treated for surgical treatment, and to evaluate the effects on the children’s hemodynamics and stress response.Methods A total of 78 children with hernia who underwent surgical treatment in our hospital from October 2019 to October 2020 were selected and divided into inhalation group and intravenous group according to the random number table method, with 39 cases in each group.The inhalation group was given sevoflurane inhalation anesthesia, and the intravenous group was given propofol intravenous anesthesia.The hemodynamics [systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR)], stress response [renin (R), norepinephrine (NE) and epinephrine (E)] were compared between the two groups during anesthesia and postoperative consciousness recovery (consciousness recovery time, orientation recovery time, first exhaust time and awake time).Results At T1, T2, and T3, the levels of NE, E, R, SBP, DBP and HR in the two groups increased compared with those at T0. The increase in the inhalation group was smaller,the difference was statistically significant (P<0.05);The recovery time of consciousness, the recovery time of orientation, the time of first exhaust and the time of waking up in the inhalation group were shorter than those in the intravenous group,the difference was statistically significant (P<0.05);The PAED scores of the inhalation group during the induction and recovery phases were lower than those of the intravenous group,the difference was statistically significant (P<0.05).Conclusion The effect of sevoflurane inhalation anesthesia for children with hernia undergoing surgical treatment is more ideal than propofol intravenous anesthesia, with less impact on the hemodynamics of the children.It can reduce the body’s stress response and shorten the recovery time of children’s consciousness.

参考文献/References:

[1]崔涛,吴思思.七氟烷吸入麻醉与异丙酚静脉麻醉对疝气手术患儿血流动力学、应激反应及麻醉效果的影响[J].中国药房,2017,28(11):1544-1547. [2]刘彦涛,廉伟,李刚,等.儿童腹腔镜疝气手术中七氟醚与舒芬太尼复合麻醉的效果及血流动力学变化分析[J].湖南师范大学学报（医学版）,2019,16(2):135-138. [3]Ahmet S,Mehmet AB,Sina F,et al.Laparoscopic Total Extraperitoneal Inguinal Hernia Repair Under Epidural Anesthesia Versus General Anesthesia[J].Surgical Laparoscopy,Endoscopy&Percutaneous Techniques,2020,30(5):471-475. [4]蒋文军,杨孟昌,徐冰.七氟醚复合舒芬太尼与氯胺酮麻醉对疝气腹腔镜手术患儿的临床效果及血液流变学分析[J].中国医院药学杂志,2016,36(10):838-840. [5]符定家,许铿,李建,等.静-吸复合麻醉加局部神经阻滞在小儿疝气手术中的应用研究[J].中国地方病防治杂志,2017,32(11):1270-1275. [6]刘少星,谢先丰,曹德钧.不同镇痛模式在幼儿疝气修补术后早期镇痛的临床效果[J].昆明医科大学学报,2020,41(2):91-95. [7]周进军,朱建民.七氟醚用于小儿腹腔镜疝手术对苏醒时间和氧化应激水平的影响[J].中国药业,2020,29(12):76-78. [8]Shahin H,Shahab H,Shahd M,et al.Meta-Analysis of Spinal Anesthesia Versus General Anesthesia During Laparoscopic Total Extraperitoneal Repair of Inguinal Hernia[J].Surgical Laparoscopy,Endoscopy&Percutaneous Techniques,2020,30(4):371-380. [9]张剑蔚,白洁,张瑞冬.丙泊酚联合氯胺酮麻醉对小儿疝气手术患者呼吸抑制不良反应及疗效的影响研究[J].山西医药杂志,2017,46(17):2097-2100. [10]刘湘玉,李继云,蒋媛媛.幼儿患者采用丙泊酚或依托咪酯全麻对认知功能的副作用比较研究[J].临床药物治疗杂志,2015,(5):53-56. [11]吴书宝,程伟.丙泊酚复合七氟醚对小儿全身麻醉术后脑指数及认知功能影响[J].中国医药导报,2020,17(19):108-111. [12]曹呈尧,王定淼.小儿疝气术后恢复的影响因素分析[J].中国妇幼保健,2019,34(8):1784-1786. [13]Zhen D,Xi YZ,Shuang QQ,et al.The comparison of dexmedetomidine and midazolam premedication on postoperative anxiety in children for hernia repair surgery:A randomized controlled trial[J].Pediatric Anesthesia,2019,29(8):843-849. [14]付小武,宋毓辉,吴娟娟.小儿全麻气管内插管在腹腔镜下疝气高位结扎术中的麻醉效果观察[J].贵州医药,2020,44(3):446-447. [15]谭宇林,曾群英,肖宇明,等.七氟醚与异丙酚用于小儿疝气手术麻醉的效果比较[J].实用临床医学,2015,12(9):39-40.

相似文献/References:

[1]唐朝.儿童先天性脊柱侧弯诊疗现状的临床研究[J].医学信息,2018,31(01):61.[doi:10.3969/j.issn.1006-1959.2018.01.022]
　TANG Chao.Clinical Study on Diagnosis and Treatment of Congenital Scoliosis in Children[J].Medical Information,2018,31(17):61.[doi:10.3969/j.issn.1006-1959.2018.01.022]
[2]韩晓利.含氟泡沫预防儿童乳牙龋齿的临床效果研究[J].医学信息,2018,31(02):7.[doi:10.3969/j.issn.1006-1959.2018.02.003]
　HAN Xiao-li.Study on the Clinical Effect of Fluoride Foam in Preventing Deciduous Dental Decay in Children[J].Medical Information,2018,31(17):7.[doi:10.3969/j.issn.1006-1959.2018.02.003]
[3]李 娟,田 鹏,刘 琦,等.血清降钙素原在儿童发热性疾病中的应用价值分析[J].医学信息,2018,31(04):102.[doi:10.3969/j.issn.1006-1959.2018.04.034]
　LI Juan,TIAN Peng,LIU Qi,et al.Analysis of the Value of Serum Procalcitonin in Children with Febrile Diseases[J].Medical Information,2018,31(17):102.[doi:10.3969/j.issn.1006-1959.2018.04.034]
[4]郭 朋,罗 聪.儿童扁平足病因、检测方法和治疗现状[J].医学信息,2018,31(05):56.[doi:10.3969/j.issn.1006-1959.2018.05.020]
　GUO Peng,LUO Cong.The Cause,Detection Method and Treatment Status of Children's Flat Foot[J].Medical Information,2018,31(17):56.[doi:10.3969/j.issn.1006-1959.2018.05.020]
[5]许海泉.生酮饮食治疗儿童难治性癫痫的临床研究[J].医学信息,2018,31(06):83.[doi:10.3969/j.issn.1006-1959.2018.06.026]
　XU Hai-quan.Clinical Study of Ketogenic Diet in Children with Refractory Epilepsy[J].Medical Information,2018,31(17):83.[doi:10.3969/j.issn.1006-1959.2018.06.026]
[6]许海泉.生酮饮食治疗儿童难治性癫痫合并智力低下的研究[J].医学信息,2018,31(07):57.[doi:10.3969/j.issn.1006-1959.2018.07.019]
　XU Hai-quan.Study on the Ketogenic Diet in the Treatment of Refractory Epilepsy in Children with Mental Retardation[J].Medical Information,2018,31(17):57.[doi:10.3969/j.issn.1006-1959.2018.07.019]
[7]许海泉.生酮饮食对不同病因及发作形式儿童难治性癫痫 疗效差异的临床观察[J].医学信息,2018,31(08):88.[doi:10.3969/j.issn.1006-1959.2018.08.027]
　XU Hai-quan.Clinical Observation of the Effect of Ketogenic Diet on the Efficacy of Children with Refractory Epilepsy Due to Different Causes and Attacks[J].Medical Information,2018,31(17):88.[doi:10.3969/j.issn.1006-1959.2018.08.027]
[8]阙禧韬.咬合诱导在牙源性错牙合畸形中的早期应用分析[J].医学信息,2018,31(10):184.[doi:10.3969/j.issn.1006-1959.2018.10.064]
　QUE Xi-tao.Early Application of Occlusal Induction in Odontogenic Malocclusion[J].Medical Information,2018,31(17):184.[doi:10.3969/j.issn.1006-1959.2018.10.064]
[9]李振宏,施海龙,林思名,等.伴中央颞区棘波的儿童良性癫痫与 微量元素的关系研究[J].医学信息,2018,31(12):90.[doi:10.3969/j.issn.1006-1959.2018.12.027]
　LI Zhen-hong,SHI Hai-long,LIN Si-ming,et al.Study on the Relationship between Children's Benign Epilepsy and Trace Elements in the Central Temporal Spikes[J].Medical Information,2018,31(17):90.[doi:10.3969/j.issn.1006-1959.2018.12.027]
[10]胡 帅,张 蕾,罗荣华.呼出气一氧化氮浓度检测在儿童咳嗽变异性哮喘中的应用[J].医学信息,2018,31(13):91.[doi:10.3969/j.issn.1006-1959.2018.13.026]
　HU Shuai,ZHANG Lei,LUO Rong-hua.Determination of Exhalation Nitric Oxide Concentration in Children with Cough Variant Asthma[J].Medical Information,2018,31(17):91.[doi:10.3969/j.issn.1006-1959.2018.13.026]

更新日期/Last Update: 1900-01-01