[1]陈 洁.乳腺癌改良根治术治疗乳腺癌的疗效及对激素水平的影响[J].医学信息,2022,35(24):121-123.[doi:10.3969/j.issn.1006-1959.2022.24.023]
　CHEN Jie.Efficacy of Modified Radical Mastectomy for Breast Cancer and its Effect on Hormone Level[J].Journal of Medical Information,2022,35(24):121-123.[doi:10.3969/j.issn.1006-1959.2022.24.023]
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乳腺癌改良根治术治疗乳腺癌的疗效及对激素水平的影响()
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医学信息[ISSN:1006-1959/CN:61-1278/R]

卷:
35卷
期数:
2022年24期
页码:
121-123
栏目:
临床研究
出版日期:
2022-12-15

文章信息/Info

Title:
Efficacy of Modified Radical Mastectomy for Breast Cancer and its Effect on Hormone Level
文章编号:
1006-1959（2022）24-0121-03
作者:
陈 洁
（太仓市第一人民医院甲乳外科，江苏 太仓 215400）
Author(s):
CHEN Jie
(Department of Thyroid and Breast Surgery,the First People’s Hospital of Taicang,Taicang 215400,Jiangsu,China)
关键词:
乳腺癌改良根治术; 游离甲状腺素; 游离三碘甲腺原氨酸
Keywords:
Modified radical mastectomy for breast cancer; Free thyroxine; Free triiodothyronine
分类号:
R737.9
DOI:
10.3969/j.issn.1006-1959.2022.24.023
文献标志码:
A
摘要:
目的 分析乳腺癌改良根治术治疗乳腺癌的疗效及对激素水平的影响。方法 选取2016年1月-2020年12月太仓市第一人民医院收治的100例乳腺癌患者作为研究对象，根据手术方式不同分为观察组和对照组，各50例。对照组采用患侧乳房切除+前哨淋巴结活检手术进行治疗，观察组采用改良根治术进行治疗，比较两组手术情况、激素水平[血清游离甲状腺素（FT4）以及游离三碘甲腺原氨酸（FT3）]、生活质量、并发症发生率及复发率。结果 观察组手术时间长于对照组（P＜0.05）；观察组FT3、FT4水平高于对照组（P＜0.05）；观察组术后生理、社会适应性及整体健康评分高于对照组（P＜0.05）；两组出血量、引流液量、住院时间、并发症发生率及随访1年复发率比较，差异无统计学意义（P＞0.05）。结论 乳腺癌改良根治术具有良好的临床疗效，能够有效改善机体激素水平，降低并发症发生率及复发率，值得临床应用。
Abstract:
Objective To analyze the effect of modified radical mastectomy for breast cancer and its influence on hormone levels.Methods A total of 100 patients with breast cancer admitted to the First People’s Hospital of Taicang from January 2016 to December 2020 were selected as study subjects. According to different surgical methods, they were divided into observation group and control group, with 50 cases in each group. The control group was treated with ipsilateral mastectomy+sentinel lymph node biopsy. The observation group was treated with modified radical mastectomy. The surgical conditions, hormone levels [serum free thyroxine (FT4) and free triiodothyronine (FT3)], quality of life, complication rate and recurrence rate were compared between the two groups.Results The operation time of the observation group was longer than that of the control group (P<0.05). The levels of FT3 and FT4 in the observation group were higher than those in the control group (P<0.05). The scores of postoperative physiology, social adaptability and overall health in the observation group were higher than those in the control group (P<0.05). There was no significant difference in blood loss, drainage volume, hospitalization time, complication rate and recurrence rate at 1 year follow-up between the two groups (P>0.05).Conclusion Modified radical mastectomy for breast cancer has good clinical efficacy, which can effectively improve the body hormone level, reduce the incidence of complications and recurrence rate, and is worthy of clinical application.

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更新日期/Last Update: 1900-01-01